丁寒锋 博士 浙江大学求是特聘教授，博士生导师 办公地址 浙江省杭州市西湖区余杭塘路866号 浙大紫金港西区海纳苑7幢A813 E-mail hfding@zju.edu.cn 研究及工作经历 2003年本科毕业于浙江大学化学系，2008年获得浙江大学博士学位，2008至2011年在新加坡科技研究局从事博士后研究和担任研究科学家。2011年8月进入浙江大学化学系工作，现为浙江大学求是特聘教授、博士生导师，浙江省化学会副理事长。国家基金委杰出青年基金、优秀青年基金获得者，入选国家“计划”。研究领域为天然产物全合成及导向天然产物的新反应方法学，在多种学术刊物上发表学术论文五十余篇。曾获得Thieme Chemistry Journals Award、ACP Lectureship Award等奖励和荣誉。 研究生招生和培养 本课题组充分重视培养学生的创新能力、解决实际问题能力和国际竞争力，已培养多名博士生前往美国Scripps研究所、美国西南医学中心、加州大学伯克利分校、芝加哥大学、莱斯大学、德国康斯坦茨大学等国际知名机构进行博士后研究，并进入985、211大学或相当研究机构开展独立科研工作，目前已有一位毕业生获得国家海外优青项目。 每年招收博士、硕士和联合培养研究生（化学、药学、生物学等专业）多名 2025年拟招收学硕/专硕 1~2 名，欢迎感兴趣的同学邮件联系（to hfding@zju.edu.cn） 欢迎本科生加入课题组进行科研训练和毕业设计！ 奖励荣誉 2022年 ACP Lectureship Award 2021年 国家基金委杰出青年科学基金 2018年 国家“计划”青年拔尖人才 2016年 国家基金委优秀青年科学基金（结题优秀） 2015年 Thieme Chemistry Journals Award 浙江省杰出青年基金（结题优秀） 2008年 浙江省高等学校科研成果一等奖 浙江大学优秀毕业生 2003年 浙江大学“竺可桢”奖学金 浙江省优秀毕业生

有机合成化学 导向天然产物（药物）的新合成方法 天然产物合成及药物化学研究

UG denotes "undergraduate student"; # denotes "equal contribution". Click on the "Article Title" to download a pdf version. 61. "Divergent Total Syntheses of Phragmalin and Khayanolide-Type Limonoids: A Torquoselective Interrupted Nazarov Approach"Peirong Rao, Dongmin Tang, Qidong Xia, Jialei Hu, Xufeng Lin, Jun Xuan,* Hanfeng Ding.* J. Am. Chem. Soc. 2025, 147, DOI: 10.1021/jacs.4c16265. 60. "Advances in the Total Syntheses of Tetraquinane and Tetraquinane-type Terpenes" Yunbo Yang, Hanfeng Ding.* Chin. J. Org. Chem. 2025, 45, DOI: 10.6023/cjoc202408029. 59. "Cooperative Iodine and Nitrate Catalyzed Oxidation of Stilbenes to α-Diketones in Water" Junfei Luo,* Yue Lv, Keqi Tang, Hanfeng Ding.* Chem. Asian J. 2024, e202401557. 58. "Bench-Stable Meisenheimer Complexes: Synthesis, Characterization, and Divergent Reactivity for Dearomatization" Wei-Long Zeng,# Qidong Xia,# Chu-Qiao Li, Ming-Yang Wang, Wang-Ye Jin, Hanfeng Ding,* Wei Li.* J. Am. Chem. Soc. 2024, 146, 30764-30770. 57. (book chapter) "[5+2] and [6+2] Cycloaddition Reaction of Alkenes, Alkynes, Allenes and 1,3-Dienes" Kai Gao, Yong Qu, Qidong Xia, Hanfeng Ding* in Comprehensive Organic Synthesis 3rd Edition, Oxford: Elsevier, 2024, DOI: 10.1016/B978-0-323-96025-0.00056-9. 56. "Five Decades of Endeavor towards Total Syntheses of Grayanane Diterpenoids" Qidong Xia, Hanfeng Ding,* Tetrahedron Lett. 2024, 145, 155160. • In honour of Prof. Tomas Maimone, 2024 Tetrahedron Young Investigator Award in Organic Synthesis 55. "A Unified Synthetic Approach to the Pleurotin Natural Products" Yong Gao, Qidong Xia, An Zhu, Wenkuan Mao, Yiming Mo, Hanfeng Ding,* Jun Xuan.* J. Am. Chem. Soc. 2024, 146, 18230-18235. • Featured in Synfacts (2024, 20, 895)[link], and selected as 'Synfact of the Month' in September, 2024 image.png 54. "Forging the Tetracyclic Core Framework of Rhodomolleins XIV and XLII: A Ring Distortion Approach" Zhen-Ning Yang,# Huijuanzi Rao,# Yuhao Yin, Shan Mu, Ziqi Jia, Hanfeng Ding.* Org. Lett. 2024, 26, 3524-3529. • Selected in Special Issue "Radical Reactions for the Construction and Transformation of Complex Molecules" 53. "Total Synthesis of (−)-Retigeranic Acid A: A Reductive Skeletal Rearrangement Strategy"Dongyu Sun,# Ruyi Chen,# Dongmin Tang,# Qidong Xia (UG), Yifan Zhao, Chun-Hui Liu, Hanfeng Ding.* J. Am. Chem. Soc. 2023, 145, 11927-11932. • Top 20 "Most Read Articles" in June, 2023 • Featured in Synfacts (2023, 19, 741)[link], and selected as 'Synfact of the Month' in August, 2023 image.png 52. "A Study Travel of Sodium Nitrite" Xiang Li (UG), Taibao Wang (UG), Ping Lu, Hanfeng Ding.* Univ. Chem. 2023, 38, 32−37. 51. "Divergent Total Syntheses of (+)-Vulgarisins A–E"Kaixiang Xu, Shan Mu, Huijuanzi Rao, Jialei Hu, Hanfeng Ding.* Angew. Chem. Int. Ed. 2023, 62, e202303668. • Top 15 "Most Accessed Articles" in April, 2023 • Highlighted by "Organic Chemistry Highlights" July 1, 2024[link] 50. "Divergent Synthetic Approach to Grayanane Diterpenoids"An Zhu,# Yumeng Lyu,# Qidong Xia(UG),# Yufei Wu, Dongmin Tang, Chi He, Guijuan Zheng, Yuanyuan Feng, Yong Wang, Guangming Yao,* Hanfeng Ding.* J. Am. Chem. Soc. 2023, 145, 8540-8549. • Featured in Synfacts (2023, 19, 642)[link] 49. "Divergent Total Syntheses of (–)-Crinipellins Facilitated by a HAT-Initiated Dowd–Beckwith Rearrangement" Yifan Zhao,# Jialei Hu,# Ruyi Chen,# Fengping Xiong (UG), Hujun Xie,* Hanfeng Ding.* J. Am. Chem. Soc. 2022, 144, 2495-2500. • Top 10 "Most Read Articles" in February & March, 2022 • Featured in Synfacts (2022, 18, 345)[link], and selected as 'Synfact of the Month' in April, 2022 image.png • Highlighted by "Organic Chemistry Highlights" February 6, 2023[link] 48. "Asymmetric Total Synthesis of Taxol" Dongyu Sun, Hanfeng Ding.* Chin. J. Org. Chem. 2021, 41, 4827-4829. (Highlight) 47. "Asymmetric Total Syntheses of (+)-Davisinol and (+)-18-Benzoyldavisinol: A HAT-Initiated Transannular Redox Radical Approach" Kuan Yu,# Fengjie Yao,# Qingrui Zeng (UG), Hanfeng Ding.* J. Am. Chem. Soc. 2021, 143, 10576-10581. • Top 5 "Most Read Articles" in July & August, 2021 • Featured in Synfacts (2021, 17, 1072)[link] • Highlighted by "Organic Chemistry Highlights" August 22, 2022[link] 46. "Asymmetric Total Syntheses of 8,9-Seco-ent-kaurane Diterpenoids Enabled by An Electrochemical ODI-[5+2] Cascade" Bingnan Wang,# Zhaobo Liu,# Zhenzhong Tong, Beiling Gao, Hanfeng Ding.* Angew. Chem. Int. Ed. 2021, 60, 14892-14896. • Hot Paper • Highlighted by "Organic Chemistry Highlights" December 27, 2021[link] 45. "Electrochemical ODI-[5+2] Cascade for the Syntheses of Diversely Functionalized Bicyclo[3.2.1]octane Frameworks" Zhaobo Liu, Jialei Hu,* Hanfeng Ding.* Org. Lett. 2021, 23, 6745-6749. 44. "Total Synthesis of (+)-Alsmaphorazine C and Formal Synthesis of (+)-Strictamine: A Photo-Fries Approach" Beiling Gao, Fengjie Yao,# Zhaodong Zhang (UG),# Hanfeng Ding.* Angew. Chem. Int. Ed. 2021, 60, 10603-10607. • Featured in Synfacts (2021, 17, 597)[link], and selected as 'Synfact of the Month' in June, 2021 image.png • Highlighted by "Organic Chemistry Highlights" November 15, 2021[link] 43. "Tetracyclic Diterpenoid Synthesis Facilitated by ODI-Cascade Approaches to Bicyclo[3.2.1]octane Skeletons" Kai Gao,# Jialei Hu,# Hanfeng Ding.* Acc. Chem. Res. 2021, 54, 875-889. • Published as part of the Acc. Chem. Res. special issue “Total Synthesis of Natural Products” 42. "Asymmetric Total Synthesis of Spirostanol Bufospirostenin A" Zhenzhong Tong, Hanfeng Ding.* Chin. J. Org. Chem. 2020, 40, 3984-3985. (Highlight) 41. "Total Synthesis of (-)-Rhodomollanol A" Jianhong Gao,# Peirong Rao,# Kaixiang Xu, Shuaifeng Wang, Yufei Wu, Chi He, Hanfeng Ding.* J. Am. Chem. Soc. 2020, 142, 4592-4597. • Top 5 "Most Read Articles" in March & April, 2020 • Top 10 "Most Read Articles" for the previous 12 months • Featured in Synfacts (2020, 16, 499) • Featured in Chin. J. Org. Chem. (2020, 40, 1394) • Highlighted by "X-MOL"[link] 40. "Total Syntheses of (+)-Stemarin and the Proposed Structures of Stemara-13(14)-en-18-ol and Stemara-13(14)-en-17-acetoxy-18-ol" Jialei Hu, Ziqi Jia, Kaixiang Xu, Hanfeng Ding.* Org. Lett. 2020, 22, 1426-1430. • Top 10 "Most Read Articles" in February, 2020 • Selected in Virtual Issue "Organic Chemistry in China: Synthetic Methodology, Natural Products, and More"[link] 39. "Recent Advances in the Total Synthesis of Cyclobutane-Containing Natural Products" Jinshan Li,# Kai Gao,# Ming Bian, Hanfeng Ding.* Org. Chem. Front. 2020, 7, 136-154. • Selected as outside front cover • Chosen as the "Best Review of 2020"