医学博士，主任医师，博士研究生导师，浙江大学医学院附属妇产科医院生殖遗传主任。目前担任中国优生科学学会常务理事、中国医师协会遗传医师分会妇幼保健专业委员会副主任委员、浙江省医学遗传学分会常委。主要从事遗传病的致病基因与发病机制研究、遗传咨询以及遗传病的分子诊断、产前诊断和胚胎植入前诊断。主持、承担国家自然科学基金、973项目子课题、国家重点研发计划项目子课题等课题；发表学术论文百余篇，其中70余篇发表在SCI刊物；获国家科技进步奖二等奖、浙江省科技进步一等奖等。 奖励荣誉 提高出生人口质量的生殖技术创建、体系优化与临床推广应用，国务院，科技进步，国家二等奖，2010.11.29（8/10）； 辅助生殖关键技术体系创新、优化及推广和应用，中国妇幼健康研究会，科技进步，省部一等奖，2016.2.19（2/13）； 出生缺陷综合防控体系创新、运用与推广，中国妇幼健康研究会，科技进步，省部一等奖，2016.2.19（4/14）； 基于二级预防策略的出生缺陷防治关键技术与示范研究，中国出生缺陷干预救助基金会，科技进步，其他，2016.8.15（4/14）；

生殖遗传 围产医学 生殖内分泌 生殖免疫

目前担任中国优生科学学会常务理事、中国医师协会遗传医师分会妇幼保健专业委员会副主任委员、浙江省医学遗传学分会常委。

代表性论文 1.作为通讯作者 (1)Yu Jialing, Chen Na, Chen Min, Shen Min, Qian Yeqing, Dong, Minyue(*), Case Report: Prenatal diagnosis of fetal tetrasomy 9p initially identified by non-invasive prenatal testing, Frontiers in Genetics, 2022, 13:1020525. (2)Yan Kai, Zhang Jiahui, Lee Pui Y, Tao Panfeng, Wang Jun, Wang Shihao, Zhou Qing*, Dong, Minyue(*), Haploinsufficiency of PSMD12 Causes Proteasome Dysfunction and Subclinical Autoinflammation, Arthritis & Rheumatology, 2022, 74(6):1083. (3)Yan Kai, Sun Yixi, Yang Yanmei, Liu Bei, Dong, Minyue(*), Case Report: Identification Pathogenic Abnormal Splicing of BBS1 Causing Bardet-Biedl Syndrome Type I (BBS1) due to Missense Mutation, Frontiers in Genetics, 2022, 13:849562. (4)Xu Min, Jin Pengzhen, Huang Yingzhi, Qian Yeqing, Lin Miaochun, Zuo Juan, Zhu Jin, Li Zhaohui*, Dong, Minyue(*), Case report: Prenatal diagnosis of fetal intracranial hemorrhage due to compound mutations in the JAM3 gene, Frontiers in Genetics, 2022, 13:1036231. (5)Wang Zhengrong, Xu Yuqing, Sun Yixi, Wang Shuang, Dong, Minyue(*), Novel homozygous silent mutation of ITGB3 gene caused Glanzmann thrombasthenia, Frontiers in Pediatrics, 2022, 10:1062900. (6)Wang Peng, Jin Pengzhen, Zhu Linyan, Chen Min, Qian Yeqing, Zeng Wenshan, Wang Miaomiao, Xu Yuqing, Xu Yanfei, Dong, Minyue(*), Prenatal diagnosis of Walker-Warburg syndrome due to compound mutations in the B3GALNT2 gene, The Journal of Gene Medicine, 2022, 24(5):e3417. (7)Sun Yixi, Qian Yangwen, Sun Haixi, Chen Min, Luo Yuqin, Xu Xiaojing, Yan Kai, Wang Liya, Hu Junjie, Dong, Minyue(*), Case Report: De novo DDX3X mutation caused intellectual disability in a female with skewed X-chromosome inactivation on the mutant allele, Frontiers in Genetics, 2022, 13:999442. (8)Chen Min, Sun Yixi, Qian Yeqing, Chen Na, Li Hongge, Wang Liya, Dong, Minyue(*), Case report: FOXP1 syndrome caused by a de novo splicing variant (c.1652+5 G>A) of the FOXP1 gene, Frontiers in Genetics, 2022, 13:926070. (9)Liu Bei, Chen Mengjia, Yang Yanmei, Huang Yingzhi, Qian Yeqing, Dong, Minyue(*), Identification of of a PAX2 mutation from maternal mosaicism causes recurrent renal disorder in siblings, Clinica Chimica Acta, 2022, 525:23. (10)Hu Junjie, Zhang Ying, Yang Yanmei, Wang Liya, Sun Yixi, Dong, Minyue(*), Case report: Prenatal diagnosis of Kagami-Ogata syndrome in a Chinese family, Frontiers in Genetics, 2022, 13:959666. (11)Hu Junjie, Yan Kai, Jin Pengzhen, Yang Yanmei, Sun Yixi, Dong, Minyue(*), Prenatal diagnosis of trisomy 8 mosaicism, initially identified by cffDNA screening, Molecular Cytogenetics, 2022, 15(1):39. (12)Fan Lihong, Jin Pengzhen, Qian Yeqing, Shen Guosong, Shen Xueping, Dong, Minyue(*), Case Report: Prenatal Diagnosis of Postaxial Polydactyly With Bi-Allelic Variants in Smoothened (SMO), Frontiers in Genetics, 2022, 13:887082. (13)Chen Shan, Xu Yuqing, Qian Yeqing, Li Zhaohui*, Dong, Minyue(*), Case Report: Novel splicing mutations in RFX5 causing MHC class II deficiency, Frontiers in Genetics, 2022, 13:978688. (14)Zhu Hui, Jin Xiaoxiao, Xu Yuqing, Zhang Weihua, Liu Xiaodan, Jin Jinglei, Qian Yeqing, Dong, Minyue(*), Efficiency of non-invasive prenatal screening in pregnant women at advanced maternal age, BMC Pregnancy and Childbirth, 2021, 21(1):86. (15)Xu Yanfei, Jin Pengzhen, Lei Yu, Qian Yeqing, Xu Yuqing, Wang Miaomiao, Jin Jinglei, Yin Yixuan, Dong, Minyue(*), Clinical Efficiency of Non-invasive Prenatal Screening for Common Trisomies in Low-Risk and Twin Pregnancies, Frontiers in Genetics, 2021, 12:661884. (16)Wu Zaigui, Wang Miaomiao, Liang Guanmian, Jin Pengzhen, Wang Peng, Xu Yuqing, Qian Yeqing, Jiang Xiuxiu, Qian Junbin, Dong, Minyue(*), Pro-Inflammatory Signature in Decidua of Recurrent Pregnancy Loss Regardless of Embryonic Chromosomal Abnormalities, Frontiers in Immunology, 2021, 12:772729. (17)Wang Miaomiao, Xu Yuqing, Wang Peng, Xu Yanfei, Jin Pengzhen, Wu Zaigui, Qian Yeqing, Bai Long, Dong, Minyue(*), Galectin-14 Promotes Trophoblast Migration and Invasion by Upregulating the Expression of MMP-9 and N-Cadherin, Frontiers in Cell and Developmental Biology, 2021, 9:645658. (18)Sun Yixi, Yang Yali, Luo Yuqin, Chen Min, Wang Liya, Huang Yingzhi, Yang Yanmei, Dong, Minyue(*), Lack of MECP2 gene transcription on the duplicated alleles of two related asymptomatic females with Xq28 duplications and opposite X-chromosome inactivation skewing, Human Mutation, 2021, 42(11):1429. (19)Qian Yeqing, Hu Gang, Chen Min, Liu Bei, Yan Kai, Zhou Caiyun, Yu Yanqin, Dong, Minyue(*), Novel deep intronic and frameshift mutations causing a TRIP11-related disorder, American Journal of Medical Genetics, 2021, 185(8):2482. (20)Jin Pengzhen, Yan Kai, Ye Shaofen, Qian Yeqing, Wu Zaigui, Wang Miaomiao, Xu Yuqing, Xu Yanfei, Dong, Minyue(*), Case Report: A Synonymous Mutation in NF1 Located at the Non-canonical Splicing Site Leading to Exon 45 Skipping, Frontiers in Genetics, 2021, 12:772958. (21)Jin Pengzhen, Gao Xiaoyang, Wang Miaomiao, Qian Yeqing, Yang Jingjin, Yang Yanmei, Xu Yuqing, Xu Yanfei, Dong, Minyue(*), Case Report: Identification of Maternal Low-Level Mosaicism in the Dystrophin Gene by Droplet Digital Polymerase Chain Reaction, Frontiers in Genetics, 2021, 12:686993. (22)Liu J, Zhang X, Wang W, Lan X, Dong, Minyue(*), Yan K, Lei Y, Chen P, Yang M, Shan Q, Jin C. Case Report: Prenatal Diagnosis of a Fetus With Harlequin Ichthyosis Identifies Novel Compound Heterozygous Variants: A Case Report. FRONT GENET 2020, 11: 608196. (23)Li HG, Fan LH, Liu B, Qian YQ, Chen M, Sun YX, Dong, Minyue(*). The association between the two more common genetic causes of spermatogenic failure: a 7-year retrospective study. ASIAN J ANDROL 2020, 22(6): 642-648. (24)Xie J, Zhu H, Chang HM, Klausen C, Dong, Minyue(*), Leung P. GDF8 Promotes the Cell Invasiveness in Human Trophoblasts by Upregulating the Expression of Follistatin-Like 3 Through the ALK5-SMAD2/3 Signaling Pathway. Front Cell Dev Biol 2020, 8: 573781. (25)Chen M, Zhang M, Qian Y, Yang Y, Sun Y, Liu B, Wang L, Dong, Minyue(*). Identification of a likely pathogenic structural variation in the LAMA1 gene by Bionano optical mapping. NPJ GENOM MED 2020, 5: 31. (26)Liu B, Chen L, Sun J, Zhang L, Chen M, Qian Y, Wang Y, Yan K, Hou L, Huang Y, Zhang D, Xu Y, Yu J, Zhang J, Dong, Minyue(*). Generation of the human induced pluripotent stem cell line (ZJUi005-A) from a patient with Pelizaeus-Merzbacher disease (PMD) carrying a novel hemizygous mutation in PLP1 gene. STEM CELL RES 2020, 45: 101791. (27)Luo Y, Lin J, Sun Y, Qian Y, Wang L, Chen M, Dong, Minyue(*), Jin F. Non-invasive prenatal screening for Emanuel syndrome. MOL CYTOGENET 2020, 13: 9. (28)7. Xu Y, Xie J, Wan L, Wang M, Xu Y, Wang H, Dong, Minyue(*). Follistatin-like 3, an activin A binding protein, is involved in early pregnancy loss. BIOMED PHARMACOTHER 2020, 121: 109577.