陈坤，浙江大学流行病与卫生统计学教授、博士生导师。省151人才第1层次人员，1993年起享受国务院特殊津贴，2006年获吴阶平医学研究奖，2009年获中国流行病学优秀奖。主要研究方向为肿瘤分子流行病学、管理流行病学和环境流行病学。担任全国高等学校预防医学专业教学指导委员会委员、中华预防医学会流行病学分会常务理事、中国抗癌协会肿瘤流行病学分会常务理事、浙江省医师协会社区医师分会副主任委员；曾任中华医学会临床流行病学与循证医学分会副主任委员、浙江省预防医学会副会长、浙江省卫生经济学会副会长、浙江省人口与健康学会副会长、浙江省预防医学会流行病学分会主任委员、浙江省医学会临床流行病学与循证医学分会首任主任委员等学术团体职务。 从事教学科研工作40余年。期间主要参加和主持完成国家级及省部级等科研项目40余项。已发表论文300余篇，其中SCI论文160余篇。作为主要完成人先后获国家科技进步奖二等奖1项，教育部科技进步奖一等奖1项，中华医学科技奖三等奖1项，浙江省科技进步奖一等奖1项等奖项10余项。主编《临床科研设计》、《医学科研方法》、《临床流行病学》、《农村公共卫生调查》、《全人全程健康管理》、《公共卫生安全》等教材、著作10余部，其他参编10余部。 出版著作 主编 临床科研设计 第1版 浙江大学出版社 2019年 主编 临床流行病学 第2版 浙江大学出版社 2018年 编委 流行病学 第8版 人民卫生出版社 2017年 编委 流行病学 中国协和医科大学出版社 2017年 编委 流行病学进展 第13卷 人民卫生出版社 2017年 编委 现场流行病学 人民卫生出版社 2017年 副主编 癌症进化发育学 第二军医大学出版社 2017年 编委 癌前病变和癌前疾病 河南科学技术出版社 2017年 编委 流行病学（双语）人民卫生出版社 2016年 编委 公共卫生发展简史 人民卫生出版社 2016年 主编 公共卫生服务基本技术与方法 人民卫生出版社2015年 编委 中国公共卫生理论与实践 人民卫生出版社 2015年 编委 土壤污染与健康 湖北科学技术出版社 2015年 编委 区域视角下的健康发展战略选择——以浙江为例的实证研究 科学出版社 2013年 主编 全人全程健康管理 科学出版社 2012年 编委 社会保障 统筹、协调、持续发展 浙江大学出版社 2012年 编委 实用结直肠癌外科学 人民卫生出版社 2012年 编委 流行病学基础(第2版) 复旦大学出版社 2011年. 主编 医学科研方法 科学出版社 2011年. 编委 流行病学进展 (第12卷) 人民卫生出版社 2010年. 编委 循证医学基础 北京大学医学出版社 2010年 主编 农村公共卫生调查 科学出版社 2009年. 编委 中国癌症筛查及早诊早治技术方案（试行） 人民卫生出版社 2009年. 编委 临床流行病学 高等教育出版社 2007年. 主编 公共卫生安全 浙江大学出版社 2007年. 主编 公共卫生案例教材 浙江大学出版社 2006年. 编委 卫生事业管理 人民大学出版社 2006年. 编委 结直肠肿瘤·基础研究与临床实践 人民卫生出版社 2006年. 主编 医学科研设计原理与方法 中国时代经济出版社2005年 主编 临床流行病学 浙江大学出版社 2000年 获荣誉称号 1993年 国务院特殊津贴 国务院 2006年 吴阶平医学研究奖流行病学专业三等奖 吴杨奖委员会 2008年 优秀科技工作者 浙江省预防医学会 2009年 中国流行病学优秀奖 中华预防医学会 流行病学分会 获得奖项 我国大肠癌高危人群防治的基础与临床应用研究 国家科技进步奖二等奖 国务院 二等奖 2005 3/12 人群大肠癌癌前病变阻断及筛查方法优化的综合研究 教育部科技进步奖一等奖 教育部 一等奖 2003 4/12 国家数字卫生关键技术和区域示范应用研究 浙江省科技进步奖一等奖 浙江省科技厅 一等奖 2014 2/13 全人健康服务流程技术研究与开发应用 浙江省医药卫生科技创新奖 浙江省卫生厅 一等奖 2012 2/24 大肠癌环境暴露和代谢酶基因多态性的分子流行病学研究 浙江省科技进步奖二等奖 浙江省政府 二等奖 2006 1/13 国人结直肠癌环境与宿主因素的流行病学研究 浙江省科技进步奖二等奖 浙江省政府 二等奖 2004 2/8 区域人群健康大数据平台的建设与应用 浙江省科技进步奖三等奖 浙江省政府 三等奖 2022 2/7 海岛居民碘营养状况的对比研究 浙江省科技进步奖三等奖 浙江省政府 三等奖 2004 1/6 人群大肠癌筛检数量化方法的建立及其实际应用评价 浙江省科技进步奖三等奖 浙江省政府 三等奖 1991 1/5

肿瘤分子流行病学 管理流行病学 环境（空间）流行病学

代表性论文 （#共同一作，*通讯作者） 1. Haiyan Jiang, Simei Zhang, Yaoyao Lin, Lin Meng, Jiayi Li, Wenqing Wang, Kaixuan Yang, Mingjuan Jin, Jianbing Wang, Mengling Tang*, Kun Chen*. Roles of serum uric acid on the association between arsenic exposure and incident metabolic syndrome in an older Chinese population. Journal of Environmental Sciences, 2025,147:332-341. 2. Yonghao Wu, Peng Shen, Zongming Yang, Luhua Yu, Lisha Xu, Zhanghang Zhu, Tiezheng Li, Dan Luo, Hongbo Lin, Liming Shui, Mengling Tang, Mingjuan Jin, Kun Chen*, Jianbing Wang *. Outdoor Light at Night, Air Pollution, and Risk of Cerebrovascular Disease: A Cohort Study in China. Stroke, 2024; 55: 990-998. 3. Shuduo Zhou, Mintao Su, Peng Shen, Zongming Yang, Pengfei Chai, Shengzhi Sun, Hongbo Lin, Liming Shui, Na Zhang, Ming Xu, Zhi-Jie Zheng, Jianbing Wang*, Zhenyu Zhang*, Kun Chen*. Association between drinking water quality and mental health and the modifying role of diet: a prospective cohort study. BMC Med, 2024; 22: 53. 4. Wenqing Wang, Kaixuan Yang, Jiayi Li, Haiyan Jiang, Simei Zhang, Yaoyao Lin, Xinhan Zhang, Mingjuan Jin, Jianbing Wang, Mengling Tang*, Kun Chen. Association between ambient temperature and risk of notifiable infectious diseases in China from 2011 to 2019. International Journal of Environmental Health Research, 2024. 5. Haiyan Jiang, Simei Zhang, Xuecheng Yao, Lin Meng, Yaoyao Lin, Fanjia Guo, Dandan Yang, Mingjuan Jin, Jianbing Wang, Mengling Tang*, Kun Chen*. Does physical activity attenuate the association between ambient PM2.5 and physical function? Science of the Total Environment, 2023, 874:162501. 6. Haiyan Jiang, Lifang Ye, Simei Zhang, Mingjuan Jin, Jianbing Wang, Mengling Tang*, Kun Chen*. The association between nutritional status and sleep quality of Chinese community-dwelling older adults. Aging Clinical and Experimental Research, 2023, 35:1945-1954. 7. Hao Bai#, Zenghao Xu#, Jiayu Li, Xiaocong Zhang, Kai Gao, Xinglin Fei, Jinhua Yang, Qilong Li, Sangni Qian, Wanting Zhang, Xiangrong Gao, Mengling Tang, Jianbing Wang, Kun Chen*, Mingjuan Jin*. Independent and joint associations of general and abdominal obesity with the risk of conventional adenomas and serrated polyps: A large population-based study in East Asia. International Journal of Cancer, 2023; 153: 54-63. 8. Zhanghang Zhu, Zongming Yang, Lisha Xu, Yonghao Wu, Luhua Yu, Peng Shen, Hongbo Lin, Liming Shui, Mengling Tang, Mingjuan Jin, Jianbing Wang*, Kun Chen*. Exposure to neighborhood walkability and residential greenness with incident fracture. JAMA Network Open, 2023; 6: e2335154. 9. Zongming Yang, Yonghao Wu, Lisha Xu, Zhanghang Zhu, Tiezheng Li, Luhua Yu, Kai Gao, Xinhan Zhang, Peng Shen, Hongbo Lin, Liming Shui, Mengling Tang, Mingjuan Jin, Yexiang Sun*, Jianbing Wang*, Kun Chen*. Age at diagnosis modifies associations of type 2 diabetes with cancer incidence and mortality: a retrospective matched-cohort study. Diabetologia, 2023; 66:1450-1459. 10. Jingjing Hu, Luhua Yu, Zongming Yang, Jie Qiu, Jing Li, Peng Shen, Hongbo Lin, Liming Shui, Mengling Tang, Mingjuan Jin, Kun Chen*. Jianbing Wang*. Long-Term Exposure to PM2.5 and Mortality: A Cohort Study in China. Toxics, 2023; 11:727. 11. Lisha Xu, Zongming Yang, Tiezheng Li, Luhua Yu, Zhanghang Zhu, Yonghao Wu, Mengling Tang, Mingjuan Jin, Kun Chen*, Jianbing Wang*. Estimation of cancer mortality attributable to excess body weight during 2006-2015 in China. Cancer Epidemiology, 2023; 84:102358. 12. Zhanghang Zhu#, Zongming Yang, Luhua Yu, Lisha Xu, Yonghao Wu, Xinhan Zhang, Peng Shen, Hongbo Lin, Liming Shui, Mengling Tang, Mingjuan Jin, Jianbing Wang*, Kun Chen*. Residential greenness, air pollution and incident neurodegenerative disease: A cohort study in China. Science of the Total Environment, 2023; 878:163173. 13. Zongming Yang, Peng Shen, Yanlin Qu, Lisha Xu, Tiezheng Li, Zhanghang Zhu, Yonghao Wu, Luhua Yu, Kai Gao, Xinhan Zhang, Xuecheng Yao, Lin Meng, Hongbo Lin, Liming Shui, Mengling Tang, Mingjuan Jin, Kun Chen*, Jianbing Wang*. Baseline and longitudinal trajectories of body-mass index and all-cause mortality among patients with type 2 diabetes. Diabetes & Metabolism, 2023; 49:101426. 14. Yonghao Wu, Peng Shen, Zongming Yang, Luhua Yu, Zhanghang Zhu, Tiezheng Li, Lisha Xu, Dan Luo, Xuecheng Yao, Xinhan Zhang, Lin Meng, Hongbo Lin, Liming Shui, Mengling Tang, Mingjuan Jin, Kun Chen*. Jianbing Wang*, Association of walkability and fine particulate matter with chronic obstructive pulmonary disease: A cohort study in China. Science of the Total Environment, 2023; 858:159780. 15. Zhanghang Zhu, Zongming Yang, Xinhan Zhang, Luhua Yu, Dandan Yang, Fanjia Guo, Lin Meng, Lisha Xu, Yonghao Wu, Tiezheng Li, Yaoyao Lin, Peng Shen, Hongbo Lin, Liming Shui, Mengling Tang, Mingjuan Jin, Jianbing Wang*, Kun Chen*. Association of walkability and NO2 with metabolic syndrome: A cohort study in China. Environment International, 2023; 171:107731. 16. Tiezheng Li, Luhua Yu, Zongming Yang, Peng Shen, Hongbo Lin, Liming Shui, Mengling Tang, Mingjuan Jin, Kun Chen*, Jianbing Wang*. Associations of Diet Quality and Heavy Metals with Obesity in Adults: A Cross-Sectional Study from National Health and Nutrition Examination Survey (NHANES). Nutrients, 2022; 14:4038. 17. Mengyin Wu, Luhua Yu, Tiezheng Li, Jieming Lu, Zongming Yang, Peng Shen, Mengling Tang, Mingjuan Jin, Kun Chen*, Jianbing Wang*. Association between short-term exposure to air pollution and ischemic stroke: A case-crossover study in China. Atmospheric Environment, 2022; 283:119173. 18. Tiezheng Li, Zhebin Yu, Lisha Xu, Yonghao Wu, Luhua Yu, Zongming Yang, Peng Shen, Hongbo Lin, Liming Shui, Mengling Tang, Mingjuan Jin, Kun Chen*, Jianbing Wang*. Residential greenness, air pollution, and incident ischemic heart disease: A prospective cohort study in China. Science of the Total Environment, 2022; 838:155881. 19. Wanting Zhang#, Kai Gao#, Freya J.I. Fowkes, Davies Adeloye, Igor Rudan, Peige Song*, Mingjuan Jin*, Kun Chen. Associated factors and global adherence of cervical cancer screening in 2019: a systemtatic analysis and modelling study. Globalization and Health, 2022; 18: 101. 20. Sangni Qian#, Shujuan Lin#, Xin Xu#, Hao Bai, Aibuta Yeerken, Xiaojiang Ying, Zhenjun Li, Xinglin Fei, Jinhua Yang, Mengling Tang, Jianbing Wang, Mingjuan Jin*, Kun Chen*. Hypermethylation of tumor suppressor lncRNA MEF2C‑AS1 frequently happened in patients at all stages of colorectal carcinogenesis. Clinical Epigenetics, 2022; 14: 111. 21. Fanjia Guo#, Mengling Tang#, Xiaofeng Wang, Zhebin Yu, Fang Wei, Xinhan Zhang, Mingjuan Jin, Jianbing Wang, Dandan Xu, Zhijian Chen*, Kun Chen*. Characteristics, sources, and health risks of trace metals in PM2.5. Atmospheric Environment, 2022, 289:119314. 22. Xinhan Zhang, Fang Wei, Zhebin Yu, Fanjia Guo, Jianbing Wang, Mingjuan Jin, Liming Shui, Hongbo Lin, Mengling Tang*, Kun Chen*. Association of residential greenness and incident depression: Investigating the mediation and interaction effects of particulate matter. Science of the Total Environment, 2022, 811:152372. 23. Fang Wei, Zhebin Yu, Xinhan Zhang, Mengyin Wu, Jianbing Wang, Liming Shui, Hongbo Lin, Mingjuan Jin*, Mengling Tang*, Kun Chen*. Long-term exposure to ambient air pollution and incidence of depression: A population-based cohort study in China. Science of the Total Environment, 2022; 804: 149986. 24. Simeng Gu#, Sangni Qian#, Shujuan Lin, Ding Ye, Qilong Li, Jinhua Yang, Xiaojiang Ying, Zhenjun Li, Mengling Tang, Jianbing Wang, Kun Chen*, Mingjuan Jin*. Promoter hypermethylation of GALR1 acts as an early epigenetic susceptibility event in colorectal carcinogenesis. Journal of Human Genetics, 2022; 67: 519-525. 25. Jiayu Li#, Liuqing You#, Zenghao Xu, Hao Bai, Xinglin Fei, Jinhua Yang, Qilong Li, Sangni Qian, Shujuan Lin, Mengling Tang, Jianbing Wang, Kun Chen*, Mingjuan Jin*. Healthy lifestyle and the risk of conventional adenomas and serrated polyps: Findings from a large colonoscopy screening population. International Journal of Cancer, 2022; 151: 67-76. 26. Shujuan Lin, Simeng Gu, Sangni Qian, Yaxin Liu, Jinghao Sheng, Qilong Li, Jinhua Yang, Xiaojiang Ying, Zhenjun Li, Mengling Tang, Jianbing Wang, Kun Chen*, Mingjuan Jin*. Genome-wide methylation profiling of lncRNAs reveals a novel progression-related and prognostic marker for colorectal cancer. Frontiers in Oncology, 2022; 11: 782077. 27. Mengyin Wu#, Mengling Tang#, Zhebin Yu, Xinli Mao, Yi Chen, Jianbing Wang, Mingjuan Jin, Chaohui Yu*, Kun Chen*. Association between short-term exposure to air pollution and peptic ulcer bleeding: A case-crossover study in China. Atmospheric Environment, 2021, 256:118438. 28. Zhebin Yu, Fang Wei, Xinhan Zhang, Mengyin Wu, Hongbo Lin, Liming Shui, Mingjuan Jin, Jianbing Wang, Mengling Tang*, Kun Chen*. Air pollution, surrounding green, road proximity and Parkinson’s disease: A prospective cohort study. Environmental Research, 2021, 197:111170. 29. Zhebin Yu#, Xinli Mao#, Mengling Tang#, Yi Chen, Mengyin Wu, Mingjuan Jin, Jianbing Wang, Lei Xu, Guoliang Ye, Jin Ding, Bin Ye, Dongya Chen, Yu Chen, Xia Chen, Xiancang Shen, Hongzhang Li, Qiang Chen, Xiaosheng Teng, Qiulong Ding, Haideng Yang, Zhe Shen, Kun Chen*, Chaohui Yu*. Association between past exposure to fine particulate matter (PM2.5) and peptic ulcer: a cross-sectional study in eastern China. Chemosphere, 2021, 265:128706. 30. Xinhan Zhang#, Mengling Tang#, Fanjia Guo, Fang Wei, Zhebin Yu, Kai Gao, Mingjuan Jin, Jianbing Wang, Kun Chen*. Associations between Air Pollution and COVID-19 epidemic during quarantine period in China. Environmental Pollution, 2021, 268:115897. 31. Jieming Lu, Mengyin Wu, Zongming Yang, Yao Zhu, Die Li, Zhebin Yu, Peng Shen, Mengling Tang, Mingjuan Jin, Hongbo Lin, Liming Shui, Kun Chen*, Jianbing Wang*. Low LDL-C levels are associated with risk of mortality in a Chinese cohort study. Endocrine, 2021; 73:563-572. 32. Zongming Yang, Mengyin Wu, Jieming Lu, Yao Zhu, Die Li, Zhebin Yu, Peng Shen, Mengling Tang, Mingjuan Jin, Hongbo Lin, Liming Shui, Kun Chen*. Jianbing Wang*, HDL-C, longitudinal change and risk of mortality in a Chinese cohort study. Nutrition, Metabolism & Cardiovascular Diseases, 2021; 9:2669-2677. 33. Mengyin Wu, Jieming Lu, Zongming Yang, Peng Shen, Zhebin Yu, Mengling Tang, Mingjuan Jin, Hongbo Lin, Kun Chen*, Jianbing Wang*. Longitudinal changes in fasting plasma glucose are associated with risk of cancer mortality: A Chinese cohort study. Cancer Medicine, 2021; 15:5321-5328. 34. Yiyi Zhou, Zhengzhong Wang, Jieming Lu, Zongming Yang, Die Li, Zhebin Yu, Peng Shen, Mengling Tang, Mingjuan Jin, Hongbo Lin, Kun Chen*. Jianbing Wang*, Effects of nighttime sleep duration and sex on the association between siesta and hypertension. Sleep Medicine, 2021; 82:200-209. 35. Mengyin Wu, Jieming Lu, Zongming Yang, Fang Wei, Peng Shen, Zhebin Yu, Mengling Tang, Mingjuan Jin, Hongbo Lin, Kun Chen*, Jianbing Wang*. Ambient air pollution and hospital visits for peptic ulcer disease in China: A three-year analysis. Environmental Research, 2021; 196:110347. 36. Zhebin Yu, Fang Wei, Mengyin Wu, Hongbo Lin, Liming Shui, Mingjuan Jin, Jianbing Wang*, Mengling Tang*, Kun Chen*. Association of long-term exposure to ambient air pollution with the incidence of sleep disorders: A cohort study in China. Ecotoxicology and Environmental Safety, 2021; 211:111956. 37. Mengyin Wu, Jianbing Wang, Yao Zhu, Jieming Lu, Die Li, Zhebin Yu, Peng Shen, Danjie Jiang, Hongbo Lin, Kun Chen*. Impact of Individual and Combined Lifestyle Factors on Mortality in China: A Cohort Study. American Journal of Preventive Medicine. 2020; 59:461-468. 38. Chengyi Lin, Die Li, Jieming Lu, Zhebin Yu, Yao Zhu, Peng Shen, Mengling Tang, Mingjuan Jin, Hongbo Lin, Liming Shui, Kun Chen*, Jianbing Wang*. Short-term associations between ambient fine particulate matter pollution and hospital visits for chronic obstructive pulmonary disease in Yinzhou District, China. Environmental Science and Pollution Research, 2020, 27:21647-21653. 39. Jieming Lu, Zhebin Yu, Xiaocong Zhang, Mengyin Wu, Shujuan Lin, Yao Zhu, Zenghao Xu, Liuqing You, Fang Wei, Mengling Tang, Mingjuan Jin, Jianbing Wang*, Kun Chen*. Association between social health status and health-related quality of life among community-dwelling elderly in Zhejiang. Health and Quality of Life Outcomes, 2020; 18:110. 40. Die Li, Jianbing Wang*, Zhebin Yu, Hongbo Lin, Kun Chen*. Air pollutants concentration and variation of blood glucose level among pregnant women in China: A cross-sectional study. Atmospheric Environment, 2020; 233:117191. 41. Zhebin Yu, Yao Zhu, Die Li, Mengyin Wu, Mengling Tang, Jianbing Wang*, Kun Chen*. Association between visit-to-visit variability of HbA1c and cognitive decline: a pooled analysis of two prospective population-based cohorts. Diabetologia, 2020; 63:85-94. 42. Fang Wei, Mengyin Wu, Sangni Qian, Die Li, Mingjuan Jin, Jianbing Wang, Liming Shui, Hongbo Lin, Mengling Tang*, Kun Chen*. Association between short-term exposure to ambient air pollution and hospital visits for depression in China. Science of the Total Environment, 2020, 724: 138207 43. Mengling Tang, Die Li, Zeyan Liew, Fang Wei, Jianbing Wang, Mingjuan Jin, Kun Chen*, Beate Ritz. The association of short-term effects of air pollution and sleep disorders among elderly residents in China. Science of the Total Environment, 2020, 708: 134846. 44. Ding Ye, Danjie Jiang, Simeng Gu, Yingying Mao, Sangni Qian, Shujuan Lin, Qilong Li, Jinhua Yang, Kunhong Zhong, Mingjuan Jin*, Kun Chen*. Evaluating the predictive value of genetic risk score in colorectal cancer among Chinese Han population. Journal of Human Genetics, 2020; 65: 271-279. 45. Danjie Jiang#, Mingjuan Jin#, Ding Ye, Yingjun Li, Fangyuan Jing, Xiaocong Zhang, Qilong Li, Kun Chen*. Polymorphisms of a novel long non-coding RNA RP11-108K3.2 with colorectal cancer susceptibility and their effects on its expression. International Journal of Biological Markers, 2020; 35: 3-9.