陈圣福 博士, 教授 浙江大学材料与化学工程学院，制药工程研究所，杭州，邮编310027 办公室电话 15958163615 E-mail schen@zju.edu.cn 陈圣福，男，1969年7月生，1991年7月毕业于华东理工大学应用化学专业，1998在中国科学院上海应用物理研究所获理学博士学位；1999年3月到2000年1月在Kansas state university从事博士后研究；2000年1月至2007年8月，在University of Washington从事博士后研究、讲师等工作；2007年9月起到浙江大学化学工程和生物工程学系工作至今，2008年被批准为博士研究生导师。 多年来集中在血液和生物相容的“抗非特异性蛋白质吸附”材料形成机理及其应用的关键问题研究, 寻求解决与生命过程密切相关的生物吸附问题。特别是对“抗非特异性蛋白质吸附”材料的形成机理的分析研究和理性设计新型“抗非特异性蛋白质吸附”材料；纳米药物载体的血液相容性和复杂体内环境中的专一性靶向研究；长效“抗非特异性蛋白质吸附”材料研究；以及膜与膜技术应用研究。迄今己在Science、J. Am. Chem. Soc.、Advanced Materials等国际主要SCI收录期刊上发表高质量的论文90余篇， 被SCI他引8800余次，反映学术活跃程度和研究工作质量的 H因子为47，论文的篇均引用数为70余次，有30篇论文被引超过100次。 欢迎有志同学加入硕士、博士和博士后研究，充分展现你的才智，共创一流团队

应用化学,生物材料

http://www.researcherid.com/rid/G-9640-2014 (可打开已发表论文最新更新及引用） 1. Zhe Tan, Shengfu Chen, Xinsheng Peng, Lin Zhang, Congjie Gao, Polyamide membranes with nanoscale Turing structures for water purification, Science 2018, 360 (6388) 518 2. Longgang Wang, Qinghua Yang, bc Yanshuai Cui, Dawei Gao, Jianxin Kang, Haotian Sun, Linlin Zhu and Shengfu Chen Highly stable and biocompatible dendrimer encapsulated gold nanoparticle catalysts for the reduction of 4-nitrophenol, NewJ.Chem., 2017, 41, 8399 3. Longgang Wang , Yanshuai Cui , Shengfu Chen , Guangzhi Wang , Dawei Gao, Yanping Liu, Qiaoyue Luo , Zhiwei Liu, Xuwu Zhang Highly water-soluble, pH sensitive and biocompatible PAMAM “dendrizyme” to maintain catalytic activity in complex medium, Materials Science and Engineering C 2017,78, 315–323 4. Guanglong Ma, Weifeng Lin, Zhefan Yuan, Jiang Wu, Haofeng Qiana, Liangbo Xua, Shengfu Chen, Development of ionic strength/pH/enzyme triple-responsive zwitterionic hydrogel of the mixed L-glutamic acid and L-lysine polypeptide for site-specific drug delivery J. Mater. Chem. B, 2017，5, 935-943 5. Hu, YC ; Liang, B; Fang, L; Ma, GL; Yang, G ; Zhu, Q ; Chen, SF; Ye, XS Antifouling Zwitterionic Coating via Electrochemically Mediated Atom Transfer Radical Polymerization on Enzyme-Based Glucose Sensors for Long-Time Stability in 37 degrees C Serum, Langmuir, 2016, 32, 11763-11770 6. Guanglong Ma, Weifeng Lin, Zhen Wang, Juan Zhang, Haofeng Qian, Liangbo Xu, Zhefan Yuan, Shengfu Chen, Development of polypeptide-based zwitterionic amphiphilic micelles for nano drug delivery, J. Mater. Chem. B, 2016 4, 5256-5264, 7. Weifeng Lin, Guanglong Ma, Nir Kampf, Zhefan Yuan, and Shengfu Chen, Development of Long-Circulating Zwitterionic Cross-Linked Micelles for Active-Targeted Drug Delivery Biomacromolecules 2016, 17, 2010−2018, 8. Weifeng Lin, Guanglong Ma, Jiang Wu, Shengfu Chen，Different in vitro and in vivo behaviors between Poly(carboxybetaine methacrylate) and poly(sulfobetaine methacrylate), Colloids and Surfaces B: Biointerfaces 146 (2016) 888–894， 9. Jiang Wu, Zecong Xiao, Chaochao He, Jingjing Zhu, Guanglong Ma, Guangzhi Wang, Hongyu Zhanga, Jian Xiao, Shengfu Chen Protein Diffusion Characteristics in the Hydrogels of Poly(ethylene glycol) and Zwitterionic Poly(sulfobetaine methacrylate) (pSBMA) Acta Biomaterialia 40，172-181 (2016) 10. Zhen Wang, Guanglong Ma, Juan Zhang, Zhefan Yuan, Longgang Wang, Matthew Bernards, Shengfu Chen, Surface protonation/deprotonation controlled instant affinity switch of nano drug vehicle (NDV) for pH triggered tumor cell targeting Biomaterials 62, 116-127, (2015) 11. Guangzhi Wang, Longgang Wang, Weifeng Lin, Zhen Wang, Juan Zhang, Fangqin Ji,Guanglong Ma, Zhefan Yuan, and Shengfu Chen, Development of Robust and Recoverable Ultralow-Fouling Coatings Based on Poly(carboxybetaine) Ester Analogue, ACS Appl. Mater. Interfaces, 7, 16938-16945 (2015) 12. Weifeng Lin, Guanglong Ma, Fangqin Ji, Juan Zhang, Longgang Wang, Haotian Suna and Shengfu Chen, Biocompatible long-circulating star carboxybetaine polymers, J. Mater. Chem. B, 3, 440, (2015) 13. Juan Zhang, Zhen Wang, Weifeng Lin, Shengfu Chen, Gene transfection in complex media using PCBMAEE-PCBMA copolymer with both hydrolytic and zwitterionic blocks, Biomaterials 35,7909-7918 (2014) 14. Wu J., Zhao C., Lin W., Hu R., Wang Q., Chen H., Li L., Chen S., and Zheng J., Binding characteristics between polyethylene glycol (PEG) and proteins in aqueous solution J. Mater. Chem. B, 2983, (2014) 15. Zhen Wang, Guanglong Ma , Juan Zhang, Weifeng Lin, Fangqin Ji , Matthew T. Bernards , and Shengfu Chen, Development of Zwitterionic Polymer-Based Doxorubicin Conjugates: Tuning the Surface Charge To Prolong the Circulation and Reduce Toxicity, Langmuir, 2014, 30 (13), pp 3764–3774 16. Weifeng Lin, Yueying He, Juan Zhang, Longgang Wang, Zhen Wang, Fangqin Ji, Shengfu Chen, Highly Hemocompatible Zwitterionic Micelles Stabilized by Reversible Cross-Linkage for Anti-Cancer Drug Delivery, Colloids and Surfaces B: Biointerfaces, 115C, 384-390 (2014). 17. Longgang Wang, Juan Zhang, Weifeng Lin, Zhen Wang and Shengfu Chen, Development of a protein mimic with peptide ligands to enhance specific sensing and targeting by the zwitterionic surface engineering of poly(amido amine) dendrimers, Advance materials interfaces, DOI: 10.1002/admi.201300059, (2014) 18. Qinghua Yang, Longgang Wang, Weifeng Lin, Guanglong Ma, Jiang Yuan, and Shengfu Chen, Development of nonfouling polypeptides with uniformly alternating charges by polycondensing the covalently bonded dimer of glutamic acid and lysine, Journal of Materials Chemistry B, 2 (5):577 - 584, (2014) 19. Jiang Wu, Chao Zhao, Rundong Hu, Weifeng Lin, Qiuming Wang, Jun Zhao, Stephanie M. Bilinovich, Thomas C. Leeper, Lingyan Li, Harry M. Cheung, Shengfu Chen, and Jie Zheng, Probing the Weak Interaction of Proteins with Neutral and Zwitterionic Antifouling Polymers, Acta Biomaterialia, 10(2):751-760, (2014) 20. Qinghua Yang, Wenchen Li, Longgang Wang, Guangzhi Wang, Zhen Wang, Lingyun Liu & Shengfu Chen Investigation of nonfouling polypeptides of poly(glutamic acid) with lysine side chainssynthesized by EDC·HCl/HOBt chemistry, Journal of Biomaterials Science, Polymer Edition, 25:14-15, 1717-1729 (2014) 21. Fangqin Ji, Weifeng Lin, Zhen Wang, Longgang Wang, Juan Zhang, Guanglong Ma, Shengfu Chen, Development of Non-Stick and Drug-Loaded Wound Dressing Based on the Hydrolytic Hydrophobic Poly(carboxybetaine) Ester Analogue, ACS Appl. Mater. Interfaces, 5 (21), 10489–10494 (2013) 22. L. Wang, Q. Yang, G. Ma, W. Lin, Z. Wang, M. Huang, S. Chen* Development of Biocompatible PAMAM ‘Dendrizyme’ to Maintain Catalytic Activity in Biological Complex Medium, Journal of Materials Chemistry B, 1, (34), 4259-4266. (2013) 23. Jiang Wu, Zhen Wang, Weifeng Lin, Shengfu Chen, Investigation of the interaction between poly(ethylene glycol) and protein molecules using low field nuclear magnetic resonance, Acta Biomaterialia 9, 6414-6420 (2013) 24. Weifeng Lin, Hui Zhang, Jiang Wu, Zhen Wang, Haotian Sun, Jiang Yuan and Shengfu Chen, A novel zwitterionic copolymer with a short poly(methyl acrylic acid) block for improving both conjugation and separation efficiency of a protein without losing its bioactivity, J. Mater. Chem. B, 1, 2482(2013) 25. Yang Zhang, Zhen Wang, Weifeng Lin, Haotian Sun, Liguang Wu, Shengfu Chen, A facile method for polyamide membrane modification by poly(sulfobetaine methacrylate) to improve fouling resistance, Journal of Membrane Science 446, 164-170 (2013) 26. Longgang Wang, Zhen Wang, Guanglong Ma, Weifeng Lin, and Shengfu Chen, Reducing the Cytotoxity of Poly(amidoamine) Dendrimers by Modification of a Single Layer of Carboxybetaine, Langmuir, 29, 8914-8921(2013)