学习经历 1997年9月-2002年7月，浙江大学医学院，本科生，获医学学士学位（预防医学专业） 2002年9月-2007年7月，浙江大学医学院，研究生，获医学博士学位（劳动卫生与环境卫生学专业） 工作经历 2007年12月-2011年3月，加拿大UBC医学院，博士后研究，从事肿瘤生物学 2011年3月-2015年12月，浙江大学医学院，副教授，从事生物电磁学、环境医学和职业卫生学研究 2015年12月-至今，浙江大学医学院，教授，从事生物电磁学、环境医学研究 陈光弟，浙江大学教授、博导，2014年-2015年国家卫生计生委人事司干部二处借调锻炼，2017年-2022年担任浙江大学公共卫生学院副院长，2021年起任浙江大学科学技术研究院基础研究与海外项目部部长，2024年起任浙江大学基础交叉研究院副院长（兼）。主要从事环境理化因素暴露健康效应及机制研究，主持国家自然科学基金项目6项，研究成果以通讯作者身份发表于环境健康、流行病学、生物电磁学等领域高水平论文40余篇，以主要完成人身份获浙江省科技进步一等奖1项、浙江省自然科学奖二等奖1项。入选浙江省“151”人才工程第二层次培养人员、浙江省科技厅“钱江人才”项目人员、浙江省卫生厅“医坛新秀”、浙江省卫生高层次创新人才等。 获奖 1. 2021年浙江省科技进步一等奖，张丹、黄荷凤、周青、陈光弟、罗琼、林俊、朱宇宁、朱波、马俊彦、刘益枫、黄赟、李静怡、吴伊青，生殖障碍精准诊疗、促进子代健康关键技术体系的创建与推广应用。 2. 2017年浙江省自然科学奖二等奖，许正平、孙文均、陈光弟、曾群力、罗建红，电磁辐射效应的频率和细胞依赖性及其干预研究。 出版著作 Adv Exp Med Biol. 2013;990 107-10. doi 10.1007/978-94-007-5896-4_7. Global protein expression in response to extremely low frequency magnetic fields. Chen G, Xu Z. Bioelectromagnetics Laboratory, Zhejiang University School of Medicine, Hangzhou, 310058, China, chenguangdi@gmail.com. Abstract Daily exposure to extremely low frequency magnetic fields (ELF MF) in the environment has raised public concerns on human health. Epidemiological studies suggest that exposure to ELF MF might associate with an elevated risk of cancer and other diseases in humans. To explain and/or support epidemiological observations, many laboratory studies have been conducted to elucidate the biological effects of ELF MF exposure and the underlying mechanisms of action. In order to reveal the global effects of ELF MF on protein expression, the proteomics approaches has been employed in this research field. In 2005, WHO organized a Workshop on Application of Proteomics and Transcriptomics in electromagnetic fields (EMF) Research in Helsinki, Finland to discuss the related problems and solutions. Later the journal Proteomics published a special issue devoted to the application of proteomics to EMF research. This chapter aims to summarize the current research progress and discuss the applicability of proteomics approaches in studying on ELF MF induced biological effects and the underlying mechanisms. PMID 23378006 [PubMed - in process] About the book Book Title Radiation Proteomics Book Subtitle The effects of ionizing and non-ionizing radiation on cells and tissues DOI 10.1007/978-94-007-5896-4_7 Print ISBN 978-94-007-5895-7 Online ISBN 978-94-007-5896-4 Series Title Advances in Experimental Medicine and Biology Series Volume 990 Series ISSN 0065-2598 Publisher Springer Netherlands Copyright Holder Springer Science+Business Media Dordrecht

生物电磁学 环境理化因素健康效应及机制研究 出生队列研究

国际生物电磁学会（BEMS）委员会成员（Board of Directors） 中国生物医学工程学会生物电磁学分会主任委员 中国生物物理学会环境与辐射生物物理分会副主任委员 中华预防医学会劳动卫生与职业病分会常务委员 第一届国家疾病预防控制局标准委员会环境健康专业委员会委员 第八届国家卫生健康委标准委员会环境健康专业委员会委员 浙江省生物医学工程学会常务理事暨生物电磁学专委会主任委员 浙江省预防医学会环境卫生专业委员会副主任委员 浙江省预防医学会劳动卫生专业委员会副主任委员 Bioelectromagnetics杂志副主编 中国公共卫生杂志编委 中国学校卫生杂志编委 中国职业医学编委

2024 1. Jiena Zhou#, Lanfei Jin#, Yexinyi Zhou, Kunhong Zhong, Kegui Huang, Qi Zhang, Jun Tang, Xue Zhang, Lihe Peng, Shuai Li, Na Lv, Dongdong Yu, Qinheng Zhu, Jing Guo, Qiong Luo, Guangdi Chen* Associations of multiple metals exposure with immunoglobulin levels in pregnant women: Hangzhou Birth Cohort Study. J Environ Sci. 2025 May, 151: 560-572 2. Yexinyi Zhou, Jiena Zhou, Yinyin He, Jiawei Fang, Jun Tang, Shuai Li, Jing Guo, Qiong Luo, Kunhong Zhong, Kegui Huang, Guangdi Chen*. Associations between prenatal metal exposure and growth rate in children: Based on Hangzhou Birth Cohort Study. Sci Total Environ. 2024 Mar 15; 916: 170164. doi: 10.1016/j.scitotenv.2024.170164. PMID: 38242450 3. Jiawei Fang, Yexinyi Zhou, Yinyin He, Jiena Zhou, Jun Tang, Qiong Luo, Jing Guo, Guangdi Chen*. Associations among neighborhood walkability, metal exposure, and sex steroid hormone levels: Results from Hangzhou Birth Cohort Study Ⅱ. Ecotoxicol Environ Saf. 2024 Jun 15; 278: 116427. doi: 10.1016/j.ecoenv.2024.116427. PMID: 38733803 4. Ying Shen#, Huyi Jin#, Fanjia Guo, Wanting Zhang, Hao Fu, Mingjuan Jin*, Guangdi Chen*. Association of Magnesium, Iron, Copper, and Zinc Levels with the Prevalence of Behavior Problems in Children and Adolescents. Biol Trace Elem Res. 2024 Feb 23. doi: 10.1007/s12011-024-04098-4. PMID: 38388752 5. Eugenia Cordelli*, Lucia Ardoino, Barbara Benassi, Claudia Consales, Patrizia Eleuteri, Carmela Marino, Maurizio Sciortino, Paola Villani, Martin H Brinkworth, Guangdi Chen, James P McNamee, Andrew W Wood, Lea Belackova, Jos Verbeek, Francesca Pacchierotti*. Effects of radiofrequency electromagnetic field (RF-EMF) exposure on male fertility: A systematic review of experimental studies on non-human mammals and human sperm in vitro. Environ Int. 2024 Mar; 185:108509. doi: 10.1016/j.envint.2024.108509. PMID: 38492496 2023 6. Min Zhao, Jin Wan, Wenzhi Qin, Xin Huang, Guangdi Chen*, Xinyuan Zhao*. A machine learning-based diagnosis modelling of type 2 diabetes mellitus with environmental metal exposure. Comput Methods Programs Biomed. 2023 Jun;235:107537. doi: 10.1016/j.cmpb.2023.107537. PMID: 37037162 7. Yue Lan, Shaomin Zhang, Yun Pan, Minmin Wang*, Guangdi Chen*. The Research Progress on the Mechanism of Anti-Tumor Immune Response Induced by TTFields. Cancers (Basel). 2023 Nov 29;15(23):5642. PMID: 38067345 8. Lanjing Xu, Jun Wang, Yang, Xinwei Li, Chen Chen, Zinan Xu, Min Zhang, Yidan Qiu, Zhuchun Zhong, Zheng Zhang, Fangyu Li, Yufei Luo, Yuebin Lyu*, Guangdi Chen*, Xiaoming Shi*. Relationship Between Physical Activity and All-Cause Mortality Among Older Adults - China, 1998-2018. China CDC Wkly. 2023 Sep 29;5(39):866-871. PMID: 37814611 9. Yi Zhu, Xin-Xin Chai, Yuanyuan Zhao, Qiao Feng, Rong Dong, Meng-Jie Shi, Jiang Zhou, Yurong Zhao, Junxuan Peng, Youjia Tian, Guangdi Chen, Chi Luo*, Jinghao Sheng*. Saturated fatty acids synergizes cadmium to induce macrophages M1 polarization and hepatic inflammation. Ecotoxicol Environ Saf. 2023 Jul 1; 259: 115040. PMID: 37235898 10. Eugenia Cordelli*, Lucia Ardoino, Barbara Benassi, Claudia Consales, Patrizia Eleuteri, Carmela Marino, Maurizio Sciortino, Paola Villani, Martin H Brinkworth, Guangdi Chen, James P McNamee, Andrew W Wood, Lea Belackova, Jos Verbeek, Francesca Pacchierotti*. Effects of Radiofrequency Electromagnetic Field (RF-EMF) exposure on pregnancy and birth outcomes: A systematic review of experimental studies on non-human mammals. Environ Int. 2023 Oct; 180:108178. PMID: 37729852 2022 11. Liling Su#, Wenpan Fang#, Xinyuan Zhao, Longtao Zhu, Lan Gao, Guangdi Chen*. Disruption of mitochondrial redox homeostasis as a mechanism of antimony-induced reactive oxygen species and cytotoxicity. Ecotoxicol Environ Saf. 2022 Jun 1; 237: 113519. PMID: 35453021. 12. Jun Tang#, Qinheng Zhu#, Yang Xu, Yexinyi Zhou, Longtao Zhu, Lanfei Jin, Weiye Wang, Lan Gao, Guangdi Chen*, Hao Zhao*. Total arsenic, dimethylarsinic acid, lead, cadmium, total mercury, methylmercury and hypertension among Asian populations in the United States: NHANES 2011-2018. Ecotoxicol Environ Saf. 2022 Aug; 241: 113776. PMID: 35738098. 13. Chunhua Weng, Haojie Dong, Rongpan Bai, Jinghao Sheng, Guangdi Chen, Kefeng Ding, Weiqiang Lin, Jianghua Chen, Zhengping Xu*. Angiogenin promotes angiogenesis via the endonucleolytic decay of miR-141 in colorectal cancer. Mol Ther Nucleic Acids. 2022 Jan 25;27:1010-1022. doi: 10.1016/j.omtn.2022.01.017. PMID: 35228896. 14. Panpan Chen#, Qiong Luo#, Yifeng Lin, Jiani Jin, Kai-Lun Hu, Feixia Wang, Jiwei Sun, Ruixue Chen, Juan Wei, Guangdi Chen, Dan Zhang*. Arsenic exposure during juvenile and puberty significantly affected reproductive system development of female SD rats. Ecotoxicol Environ Saf. 2022 Sep 1;242:113857. doi: 10.1016/j.ecoenv.2022.113857. PMID: 35809398. 15. Tian Dong#, Xinjie Chen#, Baihui Zhao, Ying Jiang, Yuan Chen, Min Lv, Yuqun Pu, Guangdi Chen, Jian Xu*, Qiong Luo*. Development of prediction models for successful external cephalic version and delivery outcome. Arch Gynecol Obstet. 2022 Jan;305(1):63-75. doi: 10.1007/s00404-021-06115-6. PMID: 34128125. 16. Yidan Qiu#, Yuebin Lv#, Miao Zhang, Saisai Ji, Bing Wu, Feng Zhao, Yingli Qu, Qi Sun, Yanbo Guo, Yuanduo Zhu, Xiao Lin, Xulin Zheng, Zheng Li, Hui Fu, Yawei Li, Haocan Song, Yuan Wei, Liang Ding, Guangdi Chen, Ying Zhu, Zhaojin Cao, Xiaoming Shi*. Cadmium exposure is associated with testosterone levels in men: A cross-sectional study from the China National Human Biomonitoring. Chemosphere. 2022 Jul 21; 307(Pt 2): 135786. doi: 10.1016/j.chemosphere.2022.135786. PMID: 35872064. 17. Li Dong, Junli Xiang, Jingyi Guo, Guangdi Chen, Guoqing Di*. Can static electric fields increase the activity of nitric oxide synthase and induce oxidative stress and damage of spleen? Environ Sci Pollut Res Int. 2022 Jan; 29(3): 4093-4100. doi: 10.1007/s11356-021-15853-8. PMID: 34398376. 2021 18. Hao Zhao, Wenjing Wu, Xue Zhang, Qinheng Zhu, Jun Tang, Hongsen He, Guangdi Chen, Jiale Qin*. Associations between molybdenum exposure and ultrasound measures of fetal growth parameters: A pilot study. Chemosphere. 2021 Apr;269:128709. PMID: 33153843 19. Qiong Luo, Yexinyi Zhou, Hao Zhao, Guangdi Chen*. Gestational blood pressure by 2017 American College of Cardiology/American Heart Association guideline and hypertension associated risks for mothers and newborns. J Hypertens. 2021 Apr 1;39(4):806-808. PMID: 33649282. 20. Fangfang Xi, Huiqi Chen, Qinqing Chen, Danqing Chen, Yuan Chen, Matthew Sagnelli, Guangdi Chen, Baihui Zhao*, Qiong Luo*. Second-trimester and third-trimester maternal lipid profiles significantly correlated to LGA and macrosomia. Arch Gynecol Obstet. 2021 Oct;304(4):885-894. doi: 10.1007/s00404-021-06010-0. Epub 2021 Mar 2. PMID: 33651156 21. Francesca Pacchierotti*, Lucia Ardoino, Barbara Benassi, Claudia Consales, Eugenia Cordelli, Patrizia Eleuteri, Carmela Marino, Maurizio Sciortino, Martin H Brinkworth, Guangdi Chen, James P McNamee, Andrew William Wood, Carlijn R Hooijmans, Rob B M de Vries. Effects of Radiofrequency Electromagnetic Field (RF-EMF) exposure on male fertility and pregnancy and birth outcomes: Protocols for a systematic review of experimental studies in non-human mammals and in human sperm exposed in vitro. Environ Int. 2021 Dec;157:106806. doi: 10.1016/j.envint.2021.106806. Epub 2021 Aug 26. PMID: 34454359 22. Tian Dong#, Xinjie Chen#, Baihui Zhao, Ying Jiang, Yuan Chen, Min Lv, Yuqun Pu, Guangdi Chen, Jian Xu*, Qiong Luo*. Development of prediction models for successful external cephalic version and delivery outcome. Arch Gynecol Obstet. 2021 Jun 14. doi: 10.1007/s00404-021-06115-6. PMID: 34128125 2020 23. Qiong Luo#, Hao Zhao#, Ying Jiang, Jing Guo, Na Lv, Jun Tang, Shuai Li, Dan Zhang*, Rongpan Bai*, Guangdi Chen*. Association of blood metal exposure with testosterone and hemoglobin: A cross-sectional study in Hangzhou Birth Cohort Study. Environ Int. 2020 Mar; 136: 105451. PMID: 31924581 24. Hao Zhao, Jun Tang, Qinheng Zhu, Hongsen He, Shuai Li, Lanfei Jin, Xue Zhang, Longtao Zhu, Jing Guo, Dan Zhang, Qiong Luo, Guangdi Chen*. Associations of prenatal heavy metals exposure with placental characteristics and birth weight in Hangzhou Birth Cohort: Multi-pollutant models based on elastic net regression. Sci Total Environ. 2020 Nov 10; 742:140613. PMID: 32640390. 25. Ruiyao Zhou, Anand Rotte, Gang Li, Xiaolei Chen*, Guangdi Chen*, Madhuri Bhandaru*. Nuclear localization of ING3 is required to suppress melanoma cell migration, invasion and angiogenesis. Biochem Biophys Res Commun. 2020 Jun 25;527(2):418-424. PMID: 32334834. 26. Hao Zhao#, Wei Gui#, Hongjuan Huang, Yue Liu, Hui Ding, Wenyan Fan, Shaoxin Huang, Wanshui Yang*, Xin Wang*, Guangdi Chen*. Association of long-term sleep habits and hypertension: a cross-sectional study in Chinese adults. J Hum Hypertens. 2020 May;34(5):378-387. PMID: 31431681. 27. Liling Su, Longtao Zhu, Zhenchao Liu, Jianyao Lou, Bing Han, Chen Lin, Dongyu Li, Jun Qian, Xinyuan Zhao*, Guangdi Chen*. The decreased permittivity of zebrafish embryos culture medium by magnetic fields did not affect early development of zebrafish embryos. Ecotoxicol Environ Saf. 2020 Apr 15; 193: 110350. PMID: 32114242. 28. Liling Su, Longtao Zhu, Guangdi Chen*. Residence near power lines and risk of Alzheimer’s dementia and Parkinson’s disease. I nt J Epidemiol. 2020 Apr 1; 49(2): 700-701. PMID: 32091087 29. Yue Fei, Yumin Jin, Xinyuan Zhao, Yiqin Wang, Jun Qian, Liling Su*, Guangdi Chen*. The relative permittivity changes of EGF by 50 Hz MF exposure neither affect the interaction of EGF with EGFR nor its biological effects. Bioelectromagnetics. 2020 Apr; 41(3): 241-246. PMID: 31951053