蔡秀军
教授
个人简介
蔡秀军,著名外科学专家,教授,主任医师,博士生导师,浙江大学医学院附属邵逸夫医院院长。兼任中华医学会外科学分会副主任委员、中国医师协会外科医师分会微创外科医师委员会主任委员、 国务院学位委员会临床医学学科评议组成员、中央保健会诊专家、科技部重点领域创新团队负责人、美国外科学院Fellow、英国皇家外科学院Fellow、教育部“长江学者”特聘教授(2009-2012)、浙江省首批“特级专家”。荣获国家技术发明二等奖1项、国家科技进步二等奖2项、教育部科技进步一等奖1项、浙江省科技进步一等奖3项、梁何利科学与技术创新奖、浙江省科学技术奖重大贡献奖、吴阶平医药创新奖等。他建立了腹腔镜刮吸解剖法肝切除术、腹腔镜下区域性肝血流阻断技术,在国际上完成首例完全腹腔镜下绕肝带法二步肝切除术,创建了国内首个微创医学学科。 出版著作 1. 蔡秀军。腹腔镜肝脏外科学。浙江大学出版社,2017,杭州 2. Cai Xiujun. Laparoscopic Hepatectomy Atlas and Technique. Springer-Verlag, 2015, Hangzhou & Heidelberg 3. Cai Xiujun. Pancreatic cancer cystic neoplasms and endocrine tumors clinical approach to periampullary cancer. WILLEY Blackwell, 2015, Oxford 4. Cai Xiujun. The ACS Multimedia Atlas of Surgery Liver Volume Laparoscopic Liver Resection for Intrahepatic Biliary Stones, 2014 5. 蔡秀军. 外科学(中国科学院教材建设专家委员会规划教材) Liver Dieases. 科学出版社,2012,北京 6. Cai Xiujun, Wang Yifan, Peng Shuyou. Open, Laparoscopic and Robotic Hepatic Transection Laparoscopic Liver Resection Using LPMOD. Springer-Verlag, 2012, Italia 7. Cai Xiujun. Hepatic Caudate Lobe Resection Laparoscopic Resection of the Caudate Lobe. Springer-Verlag, 2009, Hangzhou & Heidelberg 奖励荣誉 入选“新世纪才工程”国家级人选、“长江学者”特聘教授、卫生部有突出贡献中青年专家、国家“计划”科技创新领军人才、浙江省首批“特级专家”、浙江省151人才工程第一层次,享受国务院特殊津贴。荣获国家技术发明二等奖1项、国家科技进步二等奖2项、教育部科技进步一等奖1项、浙江省科技进步一等奖3项、梁何利科学与技术创新奖、浙江省科学技术奖重大贡献奖、吴阶平医药创新奖、“2016年优秀医院院长”。
研究领域
肝胆胰外科,微创外科,肝癌,肝再生,医疗器械
近期论文
1. Wang K, He BY, Wang W, Niu HJ, Wang YR, Cai XJ*, Yang SX. Isolated neurosarcoidosis mimicking multifocal meningiomas: a diagnosis pitfall: A case report. Medicine. 95(46)(2016): e4994. 2. Chen MY, Lu C, Wang YF, Cai XJ*. Emphysematous cholecystitis in a young male without predisposing factors: A case report. Medicine. 95(44)(2016), e5367. 3. Ji T, Li GF, Chen J, Zhao J , Li X , Lin H, Cai XJ*, Cang Y. Distinct role of interleukin-6 and tumor necrosis factor receptor-1 in oval cell- mediated liver regeneration and inflammation-associated hepatocarcinogenesis. Oncotarget. 7(41)(2016), 66635-66646. 4. Chen J, Yu YJ, Ji T, Ma R, Chen MM, Li GF, Li FB, Ding Q, Kang QS, Huang DY, Liang X , Lin H, Cai XJ*. Clinical implication of Keap1 and phosphorylated Nrf2 expression in hepatocellular carcinoma. Cancer Med. 5(10)(2016), 2678-2687. 5. Zhou SJ, Shen JL, Lin S, Liu XL, Xu M, Shi L, Wang XF, Cai XJ*. Downregulated expression of DIXDC1 in hepatocellular carcinoma and its correlation with prognosis. Tumor Biology. 37(10)(2016), 13607-13616. 6. Xu JJ, Lin H, Li GH, Sun Y, Chen J, Shi L, Cai XJ*, Chang CS. The miR-367-3p Increases Sorafenib Chemotherapy Efficacy to Suppress Hepatocellular Carcinoma Metastasis through Altering the Androgen Receptor Signals. EBioMedicine. 12(2016), 55-67. 7. Cai LX, Wei FQ, Yu YC, Cai XJ*. Can retrohepatic tunnel be quickly and easily established for laparoscopic liver hanging maneuver by Goldfinger dissector in laparoscopic right hepatectomy? J Zhejiang Univ Sci B. 17(9)(2016), 712-721. 8. Cai XJ*, Duan L, Wang YF, Jiang WB, Liang X, Yu H, Cai LX. Laparoscopic hepatectomy by curettage and aspiration: a report of 855 cases. Surg Endosc. 30(9)(2016), 4161. 9. Xu, JJ, Lin H, Li GH, Sun Y, Shi L, Ma WL, Chen J, Cai XJ*, Chang CS. Sorafenib with ASC-J9® synergistically suppresses the HCC progression via altering the pSTAT3-CCL2/Bcl2 signals. Int J Cancer. 2016. 10. Shen JL, Zhang YP, Yu H, Shen B, Liang YL, Jin RA, Liu XL, Shi L, Cai XJ*. Role of DUSP1/MKP1 in tumorigenesis, tumor progression and therapy. Cancer Med. 5(8)(2016), 2061-2068. 11. Lin S, Zhou SJ, Jiang SJ, Liu XL, Wang YF, Zheng XY, Zhou HM, Li XH, Cai XJ*. NEK2 regulates stem-like properties and predicts poor prognosis in hepatocellular carcinoma. Oncol Rep. 36(2)(2016), 853-862. 12. Lai HC, Yeh CC, Jeng LB, Huang SF, Liao PY, Lei FJ, Cheng WC, Hsu CL, Cai XJ*, Chang C, Ma WL. Androgen receptor mitigates postoperative disease progression of hepatocellular carcinoma by suppressing CD90+ populations and cell migration and by promoting anoikis in circulating tumor cells. Oncotarget. 7(29)(2016), 46448-46465. 13. Cai LX, Wei FQ, Yu YC, Yu H, Liang X, Cai XJ*. Laparoscopic Right Hepatectomy by the Caudal Approach Versus Conventional Approach: A Comparative Study. J Laparoendosc Adv Surg Tech A. 26(7)(2016), 540-547. 14. Feng YL, Xiang JF, Kong N, Cai XJ*, Xie AY. Buried territories: heterochromatic response to DNA double-strand breaks. Acta Biochim Biophys Sin. 48(7)(2016), 594-602. 15. Cai XJ*, Duan L, Wang YF, Jiang WB, Liang X, Cai LX. Laparoscopic hepatectomy by curettage and aspiration: a report of 855 cases. Surg Endosc. 30(7)(2016), 2904-2913 16. Zhao J, Chen J, Lin H, Jin RA, Liu JH, Liu XL, Meng N, Cai XJ*. The Clinicopathologic Significance of BAF250a (ARID1A) Expression in Hepatocellular Carcinoma. Pathol Oncol Res. 22(3)(2016), 453-459. 17. Shen JL, Lin H, Li GH, Jin RA, Shi L, Chen MM, Chang CS, Cai XJ*. TR4 nuclear receptor enhances the cisplatin chemo-sensitivity via altering the ATF3 expression to better suppress HCC cell growth. Oncotarget. 7(22)(2016), 32088-32099. 18. Ma L, Cai XJ*, Wang HH, Yu YL, Huang DY, Ge GJ, Hu HY, Yu SC. Laparoscopic colonic anastomosis using a degradable stent in a porcine model. World J Gastroenterol. 22(19)(2016), 4707-4715. 19. Tang JC, Feng YL, Guo T, Xie AY, Cai XJ*. Circulating tumor DNA in hepatocellular carcinoma: trends and challenges. Cell Biosci. 6(1)(2016), 32. 20. Wang JB, Sun HL, Gao L, Xie L, Cai XJ*. Evaluation of thyroid isthmusectomy as a potential treatment for papillary thyroid carcinoma limited to the isthmus: A clinical study of 73 patients. Head Neck. 38(2016), e1510-e1514. 21. Shi L, Lin H, Li GH, Jin RA, Xu JJ, Sun Y, Ma WL, Yeh SY, Cai XJ*, Chang CS. Targeting Androgen Receptor (AR)-> IL12A Signal Enhances Efficacy of Sorafenib plus NK Cells Immunotherapy to Better Suppress HCC Progression. Mol Cancer Ther. 15(4)(2016), 731-742. 22. Lai C, Jin RA, Liang X, Cai XJ*. Comparison of laparoscopic hepatectomy, percutaneous radiofrequency ablation and open hepatectomy in the treatment of small hepatocellular carcinoma. J Zhejiang Univ Sci B. 17(3)(2016), 236-246. 23. Jin RA, Wang YF, Yu H, Liang X, Cai XJ *. Total laparoscopic left hepatectomy for primary hepatolithiasis: Eight-year experience in a single center. Surgery. 159(3)(2016), 834-841. 24. Chen MY, Lin JW, Zhu HP, Zhang B, Jiang GY, Yan PJ, Cai XJ*. Covered Stents versus Uncovered Stents for Unresectable Malignant Biliary Strictures: A Meta-Analysis. Biomed Res Int. 2016, 6408067. 25. Cai LX, Tong YF, Yu H, Liang X, Liang YL, Cai XJ*. Is Laparoscopic Hepatectomy a Safe, Feasible Procedure in Patients with a Previous Upper Abdominal Surgery? Chin Med J (Engl). 129(4)(2016), 399-404. 26. Zheng X, Feng X, Cai XJ*. Effectiveness and safety of continuous wound infiltration for postoperative pain management after open gastrectomy. World J Gastroenterol. 22(5)(2016), 1902-1910. 27. Liang X , Ying HN, Wang HW, Xu HX, Yu H, Cai LX, Wang YF, Tong YF, Ji L, Luo RJ, Cai XJ*. Enhanced Recovery Program Versus Traditional Care in Laparoscopic Hepatectomy. Medicine. 95(8)(2016), e2835. 28. Hong JJ, Zhang XF, Luo RJ, Cai XJ*. The clinical risk factors associated with postoperative bile leakage after hepatectomy: a meta-analysis. Minerva Med. 107(1)(2016), 39-53. 29. Cai XJ*, Zhao J, Wang YF, Yu H, Liang X, Jin RN, Meng N, Chen J. A Left-Sided, Purely Laparoscopic Approach for Anatomic Caudate Hepatectomy: A Single-Center Experience. J Laparoendosc Adv Surg Tech A. 26(2)(2016), 103-108. 30. Qi XC, Wan YF, Zhan QT, Yang SX, Wang YR, Cai XJ*. Effect of CDKN2A/B rs4977756 polymorphism on glioma risk: a meta-analysis of 16 studies including 24077 participants. Mamm Genome. 27(1-2)(2016), 1-7. 31. Zhang XF, Liu JH, Liang X, Chen J, Hong JJ, Li LB, He Q, Cai XJ*. History and progression of Fat cadherins in health and disease. Onco Targets Ther. 9(2016), 7337-7343. 32. Feng X, Zhu KL, Liu JH, Chen J, Tang JC, Liang YL, Jin EA, Liang X, Cai XJ*. The evaluative value of Sema3C and MFN2 co-expression detected by immunohistochemistry for prognosis in hepatocellular carcinoma patients after hepatectomy. Onco Targets Ther. 9(2016), 3213-3221. 33. Chen MY, Lin JW, Zhu HP, Zhang B, Jiang GY, Yan PJ, Cai, XJ*. Covered Stents versus Uncovered Stents for Unresectable Malignant Biliary Strictures: A Meta-Analysis. Biomed Res Int. 2016, 1-8. 34. Shi L, Lin H, Li GH, Sun Y, Shen JL, Xu JJ, Lin CY, Yeh SY, Cai XJ*, Chang, CS. Cisplatin enhances NK cells immunotherapy efficacy to suppress HCC progression via altering the androgen receptor (AR)-ULBP2 signals. Cancer Lett. 373(1)(2016), 45-56. 35. Song CY, Wang JB, Cai XJ*, Gao L. Synchronous parathyroid carcinoma and papillary thyroid carcinoma: a case study and review of literature. Int J Clin Exp Pathol. 9(1)(2016), 302-309. 36. Cai XJ, Liang Xiao, Yu TN, Liang YL, Jing RN, Jiang WB, Li JB, Ying HN. Liver cirrhosis grading Child-Pugh class B: a Goliath to challenge in laparoscopic liver resection?-prior experience and matched comparisons. Hepatobiliary Surg Nutr. 4(6)(2015), 391-397. 37. Sun J, Shen Q, Lu HQ, Jiang ZN, Xu WX, Feng LF, Li L, Wang X, Cai, XJ*, Jin HC. Oncogenic Ras suppresses ING4-TDG-Fas axis to promote apoptosis resistance. Oncotarget. 6(39)(2015), 41997-42007. 38. Cai XJ*, Ying HN, Yu H, Liang X, Wang YF, Jiang WB, Li JB, Ji L. Blunt Dissection: A Solution to Prevent Bile Duct Injury in Laparoscopic Cholecystectomy. Chin Med J (Engl). 128(23)(2015),3153-3157. 39. Lai HC, Yeh CC, Jeng LB, Huang SF, Liao PY, Lei FJ, Hsu CL, Cai XJ*, Chang CS, Ma WL. Androgen receptor expression decreases recurrence of hepatocellular carcinoma after liver resection. J Gastroenterol Hepatol. 30(2015), 345. 40. Tang JC, Liu JH, Liu XL, Liang X, Cai, XJ*. Effect of fibulin-5 on adhesion, migration and invasion of hepatocellular carcinoma cells via an integrin-dependent mechanism. World J Gastroenterol. 21(39)(2015), 11127-11140. 41. Chen J, Jin RN, Zhao J, Liu JH, Ying HN, Yan H, Zhou SJ, Liang YL, Huang DY, Liang X, Yu H, Lin H, Cai XJ*. Potential molecular, cellular and microenvironmental mechanism of sorafenib resistance in hepatocellular carcinoma. Cancer Lett. 367(1)(2015), 1-11. 42. He ZF, Zhang H, Miao HW, Li ZJ, Zhou JJ, Yan XY, Cai XJ*. 1-o-acetylbritannilactone (ABL) inhibits angiogenesis and lung cancer cell growth through regulating VEGF-Src-FAK signaling. Biochem Biophys Res Commun. 464(2)(2015), 422-427. 43. Cai XJ*, Yu TN, Yu H. Staging Laparoscopy Is Not the Best Option to Identify Unresectable Gallbladder Cancer With 100% of Accuracy. Ann Surg. 262(2)(2015), e57. 44. Shen B, Yu H, Yu TN, Shen JL, Meng N, Cai XJ*. A CD52 antibody impairs mouse-transplanted intestinal tight junctions. J Surg Res. 196(2)(2015), 278-284. 45. Fang YF, Liang X, Jiang WB, Li JB, Xu JF, Cai XJ*. Cyclin B1 Suppresses Colorectal Cancer Invasion and Metastasis by Regulating E-Cadherin. Plos One. 10(5)(2015).