曹倩 照片

曹倩

主任医师

所属大学: 浙江大学

所属学院: 医学院

邮箱:
caoq@srrsh.com

个人主页:
https://person.zju.edu.cn/0000232

个人简介

曹倩,女,主任医师,博士生导师,邵逸夫医院消化内科主任。1997年毕业于中山医科大学临床医学系,获学士学位。2000年毕业于浙江大学医学院,获硕士学位。2000年起在浙江大学附属邵逸夫医院工作。2003-2004年在英国牛津大学纳菲尔德临床医学中心GIBSON胃肠实验室从事炎症性肠病遗传易感基因研究。2005年获医学科学博士学位。2006年-2008年分别在美国加州大学洛杉矶分校和德州大学西南医学中心作为访问副教授从事IBD发病机制研究。2013年在美国梅奥诊所进行IBD临床进修。入选浙江大学“新星计划人才”,浙江省“151”二层次人次,浙江省医坛新秀。长期从事IBD患者的诊断与治疗,领导邵逸夫医院炎症性肠病中心成为中国炎症性肠病卓越诊治中心。长期关注IBD的流行病学,观察疾病长程结局,以及病因学与肠道免疫方面的研究。曾承担过国家自然科学基金面上项目多项,省重点研发等多项省部级研究。代表性论文发表于Gastroenterology、Inflammatory Bowel Disease、J Exp Med、Mod Pathol等国际知名学术杂志上。

研究领域

消化内科 炎症性肠病

学术兼职

中华医学会消化病分会炎症性肠病学组顾问 浙江省医学会消化病分会炎症性肠病学组组长 亚太炎症性肠病组织理事及临床研究组委员 中华炎性肠病杂志青年学术组常务副组长 浙江省医学会消化病学分会常委 浙江省医学会消化内镜分会副主任委员(2019年5月) AOCC 临床研究委员会(2017) 浙江省医学会消化内镜分会洗消学组副组长(2019年) 浙江省医学会消化内镜分会小肠镜及胶囊内镜副组长(2019年)

近期论文

Huang LJ#, Mao XT#, Li YY#, Liu DD, Fan KQ, Liu RB, Wu TT, Wang HL, Zhang Y, Yang B, Ye CQ, Zhong JY, Chai RJ, Cao Q*, Jin J*. Multiomics analyses reveal a critical role of selenium in controlling T cell differentiation in Crohn's disease. Immunity 2021 Jul 28. (IF:31.75) Ye L, Chapman TP, Wen Z, Lin L, Qiu Y, Liu Z, Ran Z, Qian J, Wu K, Gao X, Hu P, Chen M, Travis SPL, Cao Q*. Targeted versus universal tuberculosis chemoprophylaxis in 1968 patients with inflammatory bowel disease receiving anti-TNF therapy in a tuberculosis endemic region.Aliment Pharmacol Ther 2020 Dec 12 Liu J, Gao X, Chen Y, Mei Q, Zhu L, Qian J, Hu P, Cao Q*, Incidence and risk factors for venous thrombosis among patients with inflammatory bowel disease in China: a multicenter retrospective study. Intest Res 2020 Nov 25 Ji-Hao Shi, Liang Luo, Xiao-Li Chen, Yi-Peng Pan, Zhou Zhang, Hao Fang, Ying Chen, Wen-Dong Chen, Qian Cao*. Real-world cost-effectiveness associated with infliximab maintenance therapy for moderate to severe Crohn’s disease in China. World J Gastroenterol 2020 November 7; 26(41) Xu M, Cen M, Chen X, Chen H, Liu X, Cao Q*, Correlation between Serological Biomarkers and Disease Activity in Patients with Inflammatory Bowel Disease. Biomed Res Int 2019; (IF:2.20) Chen H, Shi J, Pan Y, Zhang Z, Fang H, Chen Y, Chen W, Cao Q*, Cost-Effectiveness of Reimbursing Infliximab for Moderate to Severe Crohn’s Disease in China, Advances in Therapy. Adv Ther 2020 Jan;37(1). (IF:3.26) Chen XL, Deng J, Chen X, Wan SS, Wang Y, Cao Q*, High incidence and morbidity of Clostridium difficile infection among hospitalized patients with inflammatory bowel disease: A prospective observational cohort study. J Dig Dis 2019 Sep;20(9). (IF:1.69) Zhang Y#, Liu R-b#, Cao Q#, Fan Ke-qi#, Huang Ling-jie, Yu Jian-shuai, Gao, Zheng-jun, Huang, Tao, Zhong, Jiang-yan, Mao, Xin-tao, Wang, Fei, Xiao, Peng, Zhao, Yuan, Feng, Xin-hua, Li, Yi-yuan, Jin, Jin*. USP16-mediated deubiquitination of calcineurin A controls peripheral T cell maintenance. Journal of Clinical Investigation. 2019 Jul; 129(7):2856-2871.(共一第三,IF:13.25) Ye L, Jiang Z, Cao Q*. Massive bleeding and perforation with endoscopic multiple deep ulcers in a patient with ulcerative colitis after colectomy. Gastroenterology. 2019 Jan 10 (通讯作者,19.23) Xiao P#, Guo Y#, Zhang H, Zhang X, Cheng H, Cao Q*, Ke Y*. Myeloid-restricted ablation of Shp2 restrains melanoma growth by amplifying the reciprocal promotion of CXCL9 and IFN-γ production in tumor microenvironment. Oncogene. 2018 Sep;37(37):5088-5100. (共同通讯,IF: 6.63) Liu R, Wang M, Zhang L, Zhou W, Huang Y, Guo H, Gu Y, Chen Y, Li Y, Chen C, Wang Y, Rong L, Li J, Xu J, Cao Q*, Jiang Z*. The clinicopathologic features of chronic active Epstein-Barr virus infective enteritis. Mod Pathol. 2019 Mar;32(3):387-395. (共同通讯,IF: 6.37) Qian Cao, Chunxiao Chen, Xiang Gao, Yan Chen, Naizhong Hu, Jie Liang, Kaichun Wu. Real-world short-term effectiveness of ustekinumab in Crohn's disease: Results from a multicenter prospective study in China. Inflamm Bowel Dis. 2022 Apr 20 (第一单位) Qian Cao, Randall Tyler Mertens, Kisha Nandini Sivanathan, Xuechun Cai, Peng Xiao*. Macrophage orchestration of epithelial and stromal cell homeostasis in the intestine. Journal of Leukocyte Biology. 2022 Aug;112(2):313-331 Ye L, Jiang Z, Liu J, Zhou W, Cao Q*.Is there a new classification of IBD-adult-onset mixed IBD. Inflamm Bowel Dis. 2018 Apr 23;24(5) (IF:4.01) Zhang Y , Jiang Z , Liu R , Chen H , Wang M , Cao Q*. Chronic Active Epstein–Barr Virus Associated Enteritis May Develop into a Precancerous Disease. .Inflamm Bowel Dis 2017 05;23 (5): E19-E21.(IF:4.01) Ye L, Lin Z, Liu J, Cao Q*. Vitamin D Deficiency Is Associated with Endoscopic Severity in Patients with Crohn's Disease. Gastroenterol Res Pract. 2017 Chao K, Wang X, Cao Q, Qian J, Wu K, Zhu X, Yang H, Liang J, Lin L, Huang Z, Zhang Y, Huang Y, Sun Y, Xue X, Huang M, Hu P, Lan P, Gao X. Combined Detection of NUDT15 Variants Could Highly Predict Thiopurine-induced Leukopenia in Chinese Patients with Inflammatory Bowel Disease: A Multicenter Analysis. Inflamm Bowel Dis. 2017 Sep;23(9):1592-1599. (IF:4.01) Zhang Y, Huang L, Liu R, Wang M, Jiang Z, Zhou W, Cao Q*. Case report of a pair of siblings with cryptogenic multifocal ulcerating stenosing enteritis. Medicine (Baltimore). 2017 Aug;96(32) Cao Q, Yao J, Li H, Tao B, Cai Y, Xiao P, Cheng H, Ke Y. Cellular Phenotypic Analysis of Macrophage Activation Unveils Kinetic Responses of Agents Targeting Phosphorylation. J Biomol Screen. 2017. (IF:2.30) Yuan Zhao, Ye L. N. Li X. L. Lin Z. W. Xu Z. J. Huang Y. B. Wang M. Y. Qian J. M. Hu, P. J. Qian Cao*.Standard-dose versus low-dose azathioprine in the treatment of Crohn’s disease: A prospective randomazed study. Yu Zhang, Jingjing Xia, Peng Xiao, Journal of Digestive Diseases. 2016 Nov;17(11):747-755 Qiang Wang, Zhenzhen Wen, Qian Cao*. Risk of tuberculosis during infliximab therapy for inflammatory bowel disease, rheumatoid arthritis, and spondyloarthropathy: A meta-analysis. Experimental and Therapeutic Medicine. 2016,12:1693-1704 Haotian Chen, Yu Zhang, Zhinong Jiang, Wei Zhou, Qian Cao*. A Case Report of NK-cell Lymphopreliferation Disease(LPD) with A Wide Involvement of Digeative Tract Develop into Esptein-Barr Virus(EBV) Associated NK/T Cell Lymphoma in An Immunocompent Patient. Medicine,2016:12(95) Huang T, Gao Z, Zhang Y, Fan K, Wang F, Li Y, Zhong J, Fan HY, Cao Q, Zhou J, Xiao Y, Hu H, Jin J. J. CRL4DCAF2 negatively regulates IL-23 production in dendritic cells and limits the development of psoriasis. Exp Med. 2018 Jul 17. Zuo T, Lu XJ, Zhang Y, Cheung C. P, Lam S, Zhang F, Tang W, Ching J. Y.L, Zhao R, Chan P. K. S, Sung J. J. Y, Yu J, Chan F. K. L, Cao Q, Sheng J. Q, Ng S. C. Gut mucosal virome alterations in ulcerative colitis. Gut 2019; 68(7): 1169-79. Qian Cao, Shanshan Wan, Min Lei, Stephen Bickston, Jianfeng Cheng. Analysis of Epidemiological and Clinical Characteristics of Inflammatory Bowel Disease over 15-year period. Gastroenterology and Hepatoloogy. 2015,12(3):