白瑞良，教授（博导） 浙江大学医学院附属邵逸夫医院（双聘） 浙江大学医学院/教育部脑与脑机融合前沿科学中心 国自然优秀青年项目（主持） 国家“科技创新2030”重大专项青年首席科学家 浙江省杰出青年基金、杭州市海外高层次人才 国际医学磁共振协会(ISMRM)青年会士 海外华人医学磁共振协会(OCMRM) Young Investigator 中国生物物理学会生物磁共振分会青年创新奖（首届） 教育及工作经历 2023.01 - 至今 浙江大学医学院，教授，博士生导师 2021.01 - 至今 浙江大学附属邵逸夫医院，双聘教授 2017.10 - 2022.12， 浙江大学医学院，研究员，博士生导师 2015.09 - 2017.09， 美国国立卫生研究院，博士后(导师 Dr. Peter Basser) 2010.08 - 2015.09， 美国马里兰大学，生物物理学，博士(导师 Dr. Peter Basser) 2006.09 - 2010.07， 湖南大学，应用物理学，学士 研究领域 1. 胶质瘤“活体病理”磁共振成像技术及临床转化 2. 脑循环系统磁共振成像技术开发及调控机制研究 3. 神经活动的磁共振精准检测 研究生（硕博）招生学科 -生物医学工程 (专业代码 083100) -脑科学与脑医学（专业代码 1001Z3） -生物物理学 (专业代码 071011) 招生方向 生物医学工程、磁共振物理学、神经影像等 欢迎对神经影像技术及其临床转化方面感兴趣的本科生、研究生、博士后加入！！！

胶质瘤及其他肿瘤“活体病理”磁共振成像技术及临床转化 非造影剂依赖的血脑屏障磁共振测量方法及临床转化 人脑类淋巴循环系统测量技术及调控机制研究

RESEARCH ARTICLES IN REFEREED JOURNALS Representative Articles 1. Jia Y, Xu S, Han G, Wang B, Wang Z, Lan W, Zhao P, Gao M, Zhang Y, Jiang W, Qiu B, Liu R, Hsu Y, Sun Y, Liu C, Liu Y*, Bai R* (2022) Transmembrane water-efflux rate measured by magnetic resonance imaging as a biomarker of the expression of aquaporin-4 in gliomas. Nature Biomedical Engineering. (IF = 29.2, Q1, ) https://doi.org/10.1038/s41551-022-00960-9 . Prof. Kayvan R. Keshari from Memorial Sloan Kettering Cancer Center published a News&views paper highlighting the importance of this work. 2. Zhang Y, Wang Y, Li Z, Wang Z, Cheng J, Bai X, Hsu Y, Sun Y, Li S, Shi J, Sui B, Bai R*(2023) Vascular-water-exchange MRI (VEXI) enables the detection of subtle AXR alterations in Alzheimer's disease without MRI contrast agent, which may relate to BBB integrity. NeuroImage. 270:119951. (IF = 7.400, Q1). https://doi.org/10.1016/j.neuroimage.2023.119951 3. Li Z, Pang Z, Cheng J, Hsu Y, Sun Y, Ozarslan E, Bai R* (2022) The Direction-dependence of Apparent Water Exchange Rate in Human White Matter, NeuroImage. 247: 118831 (IF = 6.5, Q1) https://doi.org/10.1016/j.neuroimage.2021.118831 4. Bai R1*, Li Z, Sun C, Hsu Y, Liang H, Basser P (2020) Feasibility of Filter-exchange Imaging (FEXI) in Measuring Different Exchange Processes in Human Brain. NeuroImage. 219: 117039, (IF = 6.5, Q1) https://doi.org/10.1016/j.neuroimage.2020.117039 5. Xue S, Cheng Z, Han G, Sun C, Fang K, Liu Y, Cheng J, Jin X, Bai R* (2022) 2D Probabilistic Undersampling Pattern Optimization for MR Image Reconstruction. Medical Image Analysis. 17, 102346 (IF = 13.8, Q1) https://doi.org/10.1016/j.media.2021.102346 Articles List 47. Fang K, Wang Z, Xia Q, Liu Y, Wang B, Cheng Z, Cheng J, Jin X*, Bai R*, Li L*, Normalizing Flow-based Distribution Estimation of Pharmacokinetic Parameters in Dynamic Contrast-Enhanced Magnetic Resonance Imaging," in IEEE Transactions on Biomedical Engineering, https://doi.org/10.1007/s00330-023-10122-3 10.1109/TBME.2023.3318087. 46. Zhang X1, Wang Y1, Jiao B, Wang Z, Shi J, Zhang Y, Bai X, Li Z, Li S*, Bai R*, Sui B* (2023) Glymphatic system impairment in Alzheimer’s disease: associations with perivascular space volume and cognitive function, European Radiology. https://doi.org/10.1007/s00330-023-10122-3 45. Cheng Z, Hu S, Han G, Fang K, Jin X, Alfredo O, Evren Ö, Bai R*(2023) Using Deep Learning to Accelerate Magnetic Resonance Measurements of Molecular Exchange. J. Chem. Phys. 159,054201, (IF=4.4, Q1)https://doi.org/10.1063/5.0159343 44. Han G#, Zhou Y#, Zhang K, Jiao B, Hu J, Zhang Y, Wang Z, Lou M* and Bai R* (2023) Age- and time-of-day dependenceof glymphatic function in the human brain measured via two diffusion MRI methods. Front. Aging Neurosci. (IF=5.702/Q1) https://doi.org/10.3389/fnagi.2023.1173221 43. Yin Y#, Song Y#, Jia Y, Xia J, Bai R, Kong X* (2023) Sodium Dynamics in the Cellular Environment. J. Am. Chem. Soc. 2023, 145, 19, 10522–10532, (IF = 16.383, Q1). https://doi.org/10.1021/jacs.2c13271 42. Wang Z, Wang B, Li Z, Han G, Meng C, Jiao B, Guo K, Hsu Y, Sun Y, Liu Y*, Bai R* (2023) The Consistence of Dynamic Contrast-Enhanced MRI and Filter-Exchange Imaging in Measuring Water Exchange Across the Blood–Brain Barrier in High-Grade Glioma. J Magn. Reson. Imag. (IF=5.119, Q1). https://doi.org/10.1002/jmri.28729 41. Zhang Y, Wang Y, Li Z, Wang Z, Cheng J, Bai X, Hsu Y, Sun Y, Li S, Shi J, Sui B, Bai R*(2023) Vascular-water-exchange MRI (VEXI) enables the detection of subtle AXR alterations in Alzheimer's disease without MRI contrast agent, which may relate to BBB integrity. NeuroImage. (IF = 7.400, Q1). https://doi.org/10.1016/j.neuroimage.2023.119951 40. 贾银行，韩广旭，王泽君，王宝，刘英超*，白瑞良*（2022）一种高分辨AQP4分子磁共振成像技术有望无创预测胶质瘤治疗敏感性，磁共振成像，13（11）:169-170. 39. Hu J#, Wang Y#, Li Y, Chen J, Xu D, Wang L*, Bai R*（2022）Thalamic Structure and Anastomosis in Different Hemispheres of Moyamoya Disease. Frontiers in Neuroscience, 16:1058137. (IF=5.152, Q2). https://doi.org/10.3389/fnins.2022.1058137 38. Jia Y, Xu S, Han G, Wang B, Wang Z, Lan W, Zhao P, Gao M, Zhang Y, Jiang W, Qiu B, Liu R, Hsu Y, Sun Y, Liu C, Liu Y*, Bai R* (2022) Dynamic-contrast-enhanced magnetic resonance imagin for the detection of water exchange heterogeneity in glioma. Nature Biomedical Engineering. (IF = 29.2, Q1, ) https://doi.org/10.1038/s41551-022-00960-9 . 37. Wang B, Wang Z, Jia Y, Zhao P, Han G, Meng C, Li X*, Bai R*, Liu Y*(2022) Water Exchange Detected by Shutter Speed Dynamic Contrast Enhanced-MRI Help Distinguish Solitary Brain Metastasis from Glioblastoma. European Journal of Radiology. (IF=4.531, Q2) https://doi.org/10.1016/j.ejrad.2022.110526 36. Hu J, Wang Y, Zhu Y, Li Y, Chen J, Zhang Y, Xu D, Bai R*, Wang L* (2022) Preoperative Brain Functional Connectivity Predict Outcome After Revascularization in Moyamoya Disease. Neurosurgery, 92(2):344-352, (IF=5.3, Q1). https://doi.org/10.1227/neu.0000000000002205