刘钢 照片

刘钢

研究员

所属大学: 中国科学院微生物研究所

所属学院: 未知

邮箱:
liug@im.ac.cn

个人主页:
http://www.mycolab.org.cn/templates/T_second/index.aspx?nodeid=324

个人简介

组长工作经历 2008.09- 现在 中国科学院微生物研究所真菌学国家重点实验室,研究员 2007.04- 2008.08 中国科学院微生物研究所微生物资源前期开发国家重点实验室,研究员 2001.10- 2007.03 中国科学院微生物研究所,副研究员 2000.05- 2001.10 美国Texas A&M大学植物病理及微生物系,博士后 1998.09- 2000.05 西班牙Leon大学微生物系,博士后

组长教育背景 1995.09- 1998.08 中国科学院微生物研究所,遗传学,博士学位 1992.09- 1995.07 南开大学,微生物学,硕士学位 1988.09- 1992.07 南开大学,微生物学,学士学位

研究领域

主要从事丝状真菌次级代谢产物的生物合成及其调控研究

近期论文

Liu Gang, Keith Chater,Govind Chandra, Niu Guoqing, and Tan Huarong*. (2013) Molecular Regualtion of antibiotic biosynthesis in Streptomyces. Microbiology and Molecular Biology Review, 77 (1), 112-143.

Pan Yuanyuan, Lu Cheng, Dong Hailing, Yu Lingjun, Liu Gang, Tan Huarong. (2013) Disruption of rimP-SC, encoding a ribosome assembly cofactor, markedly enhances the production of several antibiotics in Streptomyces coelicolor. Microb Cell Fact. 12(1):65.

Long Liangkun, Wang Yanling, Yang Jing, Xu Xinxin, Liu Gang*. (2013) A septation related gene AcsepH in Acremonium chrysogenum is involved in the cellular differentiation and cephalosporin production. Fungal Genetics and Biology. 50:11-20.

Liu Li, Long Liang-kun, An Yang, Yang Jing, Xu Xinxin, Hu Chang-hua*, Liu Gang*. (2013) The thioredoxin reductase-encoding gene ActrxR1 is involved in the cephalosporin C production of Acremonium chrysogenum in methionine-supplemented medium. Appl Microbiol Biotechnol. 97(6):2551-2562.

Liu L, Li Y, Li L, Cao Y, Guo L, Liu G, Che Y. 2013. Spiroketals of Pestalotiopsis fici provide evidence for a biosynthetic hypothesis involving diversified Diels-Alder reaction cascades. J Org Chem. 78(7):2992-3000. doi: 10.1021/jo302804h.

Ren Jinwei, Zhang Fan, Liu Xiangyu, Li Li, Liu Gang*, Liu Xingzhong, Che Yongsheng*.(2012) Neonectrolide A, a New Oxaphenalenone Spiroketal from the Fungus Neonectria sp. Org Lett. 14(24):6226-6229.

Yang Jing, Xu Xinxin, Liu Gang*. (2012) Amplification of a MFS transporter encoding gene penT significantly stimulates penicillin production and enhances the sensitivity of Penicillium chrysogenum to phenylacetic acid. Journal of Genetics and Genomics. 39:593-602.

Long Liangkun, Yang Jing, An Yang, Liu Gang*. (2012) Disruption of a glutathione reductase encoding gene in Acremonium chrysogenum leads to reduction of its growth, cephalosporin production and antioxidative ability which is recovered by exogenous methionine. Fungal Genetics and Biology. 49: 114–122.

Xu Xinxin, Yang Jing, An Yang, Pan Yuanyuan, Liu Gang*. (2012) Over-expression of pcvA involved in vesicle-vacuolar fusion affects the conidiation and penicillin production in Penicillium chrysogenum. Biotechnol Lett. 34:519–526.

LI Erwei, ZHANG Fan, NIU Shubin, LIU Xingzhong, LIU Gang,Che Yongsheng*. 2012. A spiro[chroman-3,7'-isochromene]-4,6'(8'H)-dione from the Cordyceps-colonizing fungus Fimetariella sp. Organic Letters 14(13):3320-3323.

An Yang, Dong Hailing, Liu Gang*. (2012) Expression of cefF significantly decreased deacetoxycephalosporin C formation during cephalosporin C production in Acremonium chrysogenum. J Ind Microbiol Biotechnol. 39:269–274.