1988年9月─1992年7月 湖南师范大学化学系，理学学士 1992年7月─1997年7月 湖南省邵阳师范高等专科学校，讲师 1997年8月─2000年7月 上海化工研究院，硕士 2000年8月─2003年7月 中科院上海有机所，理学博士 2003年8月─2005年7月 美国University of Idaho，博士后 2005年9月─ 中科院上海有机所，研究员，博士生导师

含氟试剂的发展及其应用研究 高纯金属氟盐制备及其应用研究 萃取化学 全氟醚生胶的制备

Mu, Xian; Lin, Jin-Hong*; Xiao, Ji-Chang*“Desulfurization of Thiols for Nucleophilic Substitution”Org. Lett. 2024, 26, 28, 6065–6069. Wang, Zheng; Lin, Jin-Hong*; Xiao, Ji-Chang*“Photocatalytic Keto- and Amino-Trifluoromethylation of Alkenes”Org. Lett. 2024, 26, 1980-1984. Wang, Jian‐tao; Wang, Xin‐ru; Ren, Jiao‐qi; Lin, Jin‐hong; Yu, Zhong‐yu; Huang, Shan‐shan; Hu, Yue; Fu, Jia‐yu; Wang, Meng; Zhang, Yan‐li; Wang, Xue‐chun; Guo, Jing‐chun*; Xiao, Ji‐chang*; Hou‐guang Zhou*“S‐9‐PAHSA's neuroprotective effect mediated by CAIII suppresses apoptosis and oxidative stress in a mouse model of type 2 diabetes”CNS Neurosci Ther. 2024, 30, e14594. Shi, Hua-Yi; Hu, Jia-Lu; Zheng, Jian; Cai, Ji; Chen, Hongbin*; Lin, Jin-Hong*; Xiao, Ji-Chang*“Kilogram-Scale Synthesis of Ph3P+CF2CO2-”Org. Process Res. Dev. 2024, 28, 487-491. Liu, Chao; Guo, Yong; Xiao, Ji-Chang* “The legacy of Prof. Qing-Yun Chen: Organofluorine chemistry” Chem, 2024, 10, 7-18. Zheng, Jian; Lin, Jin-Hong*; Xiao, Ji-Chang*“Difluorocarbene-based Trifluoromethylthiolation of Aryl and Alkenyl Iodides”Acta Chim. Sinica 2024, 82, 115-118. DOI: 10.6023/A23080384 Pan, Wen-Jie; Yu, Jiao; Cao, Weiguo*; Xiao, Ji-Chang*; Lin, Jin-Hong* “Difluorocarbene as a C-F source for the Construction of Fluorinated Benzothiazoles” Org. Chem. Front. 2024, 11, 120-126. Jin, Jin; Liang, Xujun; Bi, Wu; Liu, Ruijie; Zhang, Sai; He, Yi; Xie, Qingming; Liu, Shilei; Xiao, Ji-Chang*; Zhang, Pengfei*“Identification of a Difluorinated Alkoxy Sulfonyl Chloride as a Novel Antitumor Agent for Hepatocellular Carcinoma through Activating Fumarate Hydratase Activity” Pharmaceuticals 2023, 16, 1705. Tang, Wei-Ying; Zheng, Xing; Yao, Xu; Lin, Jin-Hong*; Zheng, Qu-Tong*; Xiao, Ji-Chang*“Ph3P/ICH2CH2I-promoted reductive deoxygenation of alcohols”Org. Biomol. Chem. 2023, 21, 8989-8992. Hu, Jia-Lu; Fu, Mu-Xian; Xiao, Ji-Chang*; Lin, Jin-Hong*“Thiocarbonyl fluoride generated in situ from difluorocarbene for cyclization of vicinal X-H substituted amines (X = N, O or S)”J. Fluorine Chem. 2023, 272, 110212. Zhang, Min; Li, Qiang; Lin, Jin-Hong; Xiao, Ji-Chang* “Difluoroalkylation/Lactonization of Alkenes with BrCF2CO2K via Photoredox Catalysis: Access to α,α-Difluoro-γ-lactones”Chin. J. Chem. 2023, 41, 2819-2824. Xiang, Yi-Jun; Liu, Shun; Zhou, Jing; Lin, Jin-Hong*; Yao, Xu*; Xiao, Ji-Chang* “Dehydroxylative Sulfonylation of Alcohols”J. Org. Chem. 2023, 88, 4818-4828. Luo, Ling; Lin, Jin-Hong*; Xiao, Ji-Chang*“Dehydroxylative Cyanation of Alcohols Promoted by Triphenyphosphine/1,2-Diiodoethane”Synlett 2023, 34, 1593-1596.DOI: 10.1055/a-2029-0694 Chen, Ling-Ying; Pan, Peng-Fei; Lin, Jin-Hong*; Jin, Chuan-Ming*; Xiao, Ji-Chang*“Tf2O as a CF3 Source for the Synthesis of Trifluoromethoxylation Reagent nC4F9SO3CF3”J. Org. Chem. 2023, 88, 3346-3352. Yang, Yi-Fei; Xiao, Fang; Lin, Jin-Hong; Xiao, Ji-Chang*“The Shuttle of Sulfur Dioxide: Iridium/Copper-Cocatalyzed Trifluoromethylfluorosulfonylation of Alkenes”Adv. Synth. Catal. 2023, 365, 301-306. Liu, Mingyang; Zou, Dan; Yu, Donghai; Xiang, Shaoji; Deng, Yuefeng; Chen, Ji*; Xiao, Jichang*“Synthesis of new extractant P113 for cerium(IV) extraction and higher separation over thorium from bastnaesite”Sep. Purif. Technol. 2023, 317, 123909. Yu, Donghai; An, Huaying; Du, Ruobing; Li, Linyan; Xu, Shengming; Xiao, Jichang* “A Highly Efficient Heavy Rare Earths Extractant——P227” J. Chin. Soc. Rare Earths 2022, 40, 976-987. Lin, Jinhong; Xiao, Jichang*.“Photoredox Catalytic Radical Fluorosulfonylation of Olefins”Chin. J. Org. Chem. 2022, 42, 2593-2595. 2022, 42(8), 2593-2595.DOI: 10.6023/cjoc202200041 Zhang, Feng-Xu; Lin, Jin-Hong*; Xiao, Ji-Chang*.“Difluoromethylsulfonyl Imidazolium Salt for Difluoromethylation of Alkenes”Org. Lett. 2022, 24, 7611-7616. Yang, Xin-Jun; Lin, Jin-Hong*; Xiao, Ji-Chang*.“Trifluoromethylsulfonyl pyridinium salt for trifluoromethythiolation of indoles”J. Fluorine Chem. 2022, 263, 110047. Zhang, Wei; Deng, Xiaoyun; Zhang, Feng-Xu; Lin, Jin-Hong; Xiao, Ji-Chang*; Liang, Steven H.*.“Synthesis and 18F Labeling of Alkenyl Sulfonyl Fluorides via an Unconventional Elimination Pathway”Org. Lett. 2022, 24, 4992-4997. Hao, Fei; Zhang, Tian; Yu, Donghai; Yang, Xiaodeng; Jiang, Hua-Wei*; Xiao, Ji-Chang*; Chen, Qing-Yun.“Porphyriynes: 18-π-Conjugated Macrocycles Incorporating a Triple Bond”Org. Lett. 2022, 24, 1716-1721. Qian, Bai-Yu; Zhang, Wei; Lin, Jin-Hong*; Cao, Weiguo*; Xiao, Ji-Chang*. “anti-Markovnikov Iodofluorination of Alkenes”Chem. Asian J. 2022, 17, e202200184. Xiao, Fang; Lin, Jin-Hong; Hao, Fei*; Zheng, Xing*; Guo, Yu*; Xiao, Ji-Chang*. “Visible light mediated C-H trifluoromethylation of (hetero)arenes”Org. Chem. Front. 2022, 9, 1982-1985. Tan, Jiang-Pin; Lin, Jin-Hong; Hao, Fei*; Xiao, Ji-Chang*. “Heptafluoroisopropylthiolation of benzyl halides”J. Fluorine Chem. 2022, 255-256, 109966. Zhu,Yu-Rong;Lin,Jin-Hong*;Xiao,Ji-Chang*.“Triphenylphosphine/1,2-Diiodoethane-Promoted Formylation of Indoles with N,N -Dimethylformamide” Synlett 2022, 33, 259-263.2021.10.20 DOI: 10.1055/a-1675-1043 Lin, Jinhong; Xiao, Jichang*. “Cu-Catalyzed Asymmetric Difluoromethylation of Amino Acids with Difluorocarbene” Chin. J. Org. Chem. 2021, 41, 3346-3348.  2021, 41(8), 3346-3348. 2012.09.02 DOI: 10.6023/cjoc202100062 Yang, Yi-Fei; Lin, Jin-Hong*; Xiao, Ji-Chang* “Starting from Styrene: A Unified Protocol for Hydrotrifluoromethylation of Diversified Alkenes” Org. Lett. 2021, 23, 9277-9282.DOI: 10.1021/acs.orglett.1c03630 Zong, Guo-qiang; Xiang, Shao-Ji; Cui, Zhen-Hua; Wang, Rong-Rong; Lu, Ren-Jie; Zhang, Ting; Xiao, Ji-Chang* “Preparation of the nuclear-pure grade 7LiF” Chem. Res. Appl. 2021, 33, 2240-2246.   2021.12.08 DOI: 10.3969/j.issn.1004-1656.2021.11.025 Zong, Guoqiang; Wang, Rongrong; Cui, Zhenhua; Lu, Renjie; An Huaying; Zhang, Ting; Xiao, Jichang* “Determination of Oxygen Content in 7LiF by Inert Gas Fusing-Infrared Spectroscopy” Chinese J. Inorg. Anal. Chem. 2021, 11, 103-106.  2021, 11(6), 103-106. 2021.12.17 DOI: 10.3969/j.issn.2095-1035.2021.06.016 Zhang, Min; Lin, Jin-Hong; Xiao, Ji-Chang* “HCF2Se/HCF2S Installation by Tandem Substitutions from Alkyl Bromides” J. Org. Chem. 2021, 86, 13153-13159. 2021.09.03 DOI: 10.1021/acs.joc.1c01718 Zhang, Min; Lin, Jin-Hong; Xiao, Ji-Chang* “A Readily Available Trifluoromethylation Reagent and Its Difunctionalization of Alkenes” Org. Lett. 2021, 23, 6079-6083. 2021.07.23 DOI: 10.1021/acs.orglett.1c02146 Britton, Robert; Gouverneur, Veronique; Lin, Jin-Hong; Meanwell, Michael; Ni, Chuanfa; Pupo, Gabriele; Xiao, Ji-Chang; Hu, Jinbo* “Contemporary synthetic strategies in organofluorine chemistry” Nature Reviews Methods Primers, 2021, 1, 48. 2021.07.08 DOI: 10.1038/s43586-021-00042-1 Zhou, Wei; Pan, Wen-Jie; Chen, Jie; Zhang, Min; Lin, Jin-Hong*; Cao, Weiguo*; Xiao, Ji-Chang* “Transition-metal difluorocarbene complexes” Chem. Commun. 2021, 57, 9316-9329. 2021.08.27 DOI: 10.1039/D1CC04029D Hao, Fei; Shang, Xueyun; Liu, Zhenwei; Zhang, He*; Lin, Jin-Hong*; Xiao, Ji-Chang* “Rh-catalyzed tunable defluorinative borylation” Chem. Commun. 2021, 57, 7124-7127. 2021.06.17 DOI: 10.1039/d1cc02079j He, Guowen; Xiao, Xuan; Jin, Han-Zhou; Lin, Jin-Hong*; Zhong, Tongsheng*; Zheng, Xing*; Xiao, Ji-Chang* “Ph2S/selectfluor-promoted deoxydifluorination of aldehydes” Tetrahedron 2021, 83, 131963. 2021.01.30 DOI: 10.1016/j.tet.2021.131963 Wu, Wen-Feng; Lin, Jin-Hong*; Xiao, Ji-Chang*; Cao, Yu-Cai; Ma, Yanfang “Recent Advances in the Synthesis of CF3- or HCF2-Substituted Cyclopropanes” Asian J. Org. Chem. 2021, 10, 485-495. 2021.01.27 DOI: 10.1002/ajoc.202000723 Zhang, Min; Lin, Jin-Hong; Jin, Chuan-Ming*; Xiao, Ji-Chang* “Difluorocarbene-based cyanodifluoromethylation of alkenes induced by a dual-functional Cu-catalyst” Chem. Commun. 2021, 57, 2649–2652. 2021.02.01 DOI: 10.1039/d1cc00160d Shang, Xue-Yun; An, Hua-Ying; Zhang, Ting; Lin, Jin-Hong; Hao, Fei*; Yu, Dong-Hai*; Xiao, Ji-Chang*; Li, Tian-Duo* “Evaluating and understanding the affinity of metal ions to water and ammonia using density functional theory calculation” Chem. Phys. Lett. 2021, 768, 138398. 2021.02.01 DOI: 10.1016/j.cplett.2021.138398 Xiao, Xuan; Yao, Xu; Yu, Jiao; Tang, Ting; Xiao, Can; Gu, Jinying; Lin, Jin-Hong*; Zheng, Xing*; Xiao, Ji-Chang* “A one-step synthesis of gem-difluoroolefins from alcohols” J. Fluorine Chem. 2020, 240, 109649. 2020.09.25 DOI: 10.1016/j.jfluchem.2020.109649 Xu, Zhi-Wei; Zhang, Wei; Lin, Jin-Hong*; Jin, Chuan-Ming*; Xiao, Ji-Chang* “Pd-catalyzed transfer of difluorocarbene for three component cross-coupling” Chin. J. Chem. 2020, 38, 1647-1650. 2016.08.12 DOI: 10.1021/acs.orglett.6b02141 Song, Hai-Xia; Tian, Ze-Yu; Xiao, Ji-Chang; Zhang, Cheng-Pan* “Tertiary-Amine-Initiated Synthesis of Acyl Fluorides from Carboxylic Acids and CF3SO2OCF3” Chem. Eur. J. 2020, 26, 16261-16265. 2020.09.20 DOI: 10.1002/chem.202003756 Zhang, Wei; Gu, Yu-Cheng; Lin, Jin-Hong*; Xiao, Ji-Chang* “Dehydroxylative Fluorination of Tertiary Alcohols” Org. Lett. 2020, 22, 6642-6646. 2020.07.21 Lin, Jin-Hong; Xiao, Ji-Chang* “Fluorinated Ylides/Carbenes and Related Intermediates from Phosphonium/Sulfonium Salts” Acc. Chem. Res. 2020, 53, 1498-1510. 2020.04.30 He, Guowen; Jiang, Yan-Hua; Xiao, Xuan; Lin, Jin-Hong*; Zheng, Xing*; Du, Ruo-Bing; Cao, Yu-Cai; Xiao, Ji-Chang* “Difluorocarbene-based trifluoromethylthiolation of terminal alkynes” J. Fluorine Chem. 2020, 230, 109437. 2020.12.13 DOI: https://doi.org/10.1016/j.jfluchem.2019.109437 Liu, Yongan; Yu, Donghai; Guo, Yong; Xiao, Ji-Chang; Chen, Qing-Yun*; Liu, Chao* “Arenesulfonyl Fluoride Synthesis via Copper-Catalyzed Fluorosulfonylation of Arenediazonium Salts” Org. Lett. 2020, 22, 2281-2286. 2020.02.06 DOI: https://dx.doi.org/10.1021/acs.orglett.0c00484 Xiang, Ya-Qing; Yao, Xu; Lin, Jin-Hong; Ou, Xiao-Jian; Li, Rong; Zhou, Yu-Sheng*; Yu, Dong-Hai*; Xiao, Ji-Chang* “Extraction Behavior of Acidic Phosphorus-Containing Compounds to Some Metal Ions: A Combination Research of Experimental and Theoretical Investigations” J. Phys. Chem. A 2020, 124, 5033–5041. 2020.05.21 DOI: 10.1021/acs.jpca.0c01594 Zhang, Wei; Lin, Jin-Hong; Zhang, Pengfei*; Xiao, Ji-Chang* “A convenient reagent for the conversion of aldoximes into nitriles and isonitriles” Chem. Commun. 2020, 56, 6221-6224. 2020.04.22 DOI: 10.1039/d0cc00188k Zhang, Yin-Xiang; Xiao, Xuan; Fu, Zhi-Hong; Lin, Jin-Hong*; Guo, Yu*; Yao, Xu*; Cao, Yu-Cai; Du, Ruo-Bing; Zheng, Xing*; Xiao, Ji-Chang* “Difluorocarbene-based cyanation of aryl iodides” Synlett 2020, 31, 713-717. 2020.02.03 DOI: 10.1055/s-0039-1691590 Zhang, Wei; Lin, Jin-Hong; Wu, Wenfeng*; Cao, Yu-Cai; Xiao, Ji-Chang* “Dehydroxylative trifluoromethylthiolation, trifluoromethylation, and difluoromethylation of alcohols” Chin. J. Chem. 2020, 38, 169-172. doi: 10.1002/cjoc.201900364 Xiao, Xuan; Zheng, Zi-Tong; Li, Ting; Zheng, Jing-Lin; Tao, Ting; Chen, Li-Mei; Gu, Jin-Ying; Yao, Xu*; Lin, Jin-Hong*; Xiao, Ji-Chang* “Recent advances in difluoromethylthiolation” Synthesis 2020, 52, 197-207. DOI: 10.1055/s-0039-1690714 Wu, Bi; Xiao, Ji-chang; Liu, Rui-jie; Zhou, Liu-ying; Zhang, Sai; Yang, Mei; Zhang, Peng-fei* “Identification of a 3,3-difluorinated tetrahydropyridinol compound as a novel antitumor agent for hepatocellular carcinoma acting via cell cycle arrest through disturbing CDK7-mediated phosphorylation of Cdc2” Invest. New Drugs 2020, 38, 287-298. doi:10.1007/s10637-019-00792-6