常钰磊
博导
个人简介
2008-09--2013-06 吉林大学 博士 2004-09--2008-06 吉林大学 学士 科研项目 (1)具有双模成像功能的癌细胞敏感的光子纳米材料及其医学应用, 参与, 国家级, 2018-01--2021-12 (2)均相免疫分析用上转换发光标记适配子的新型纳米生物光开关构建及基础问题研究, 主持, 国家级, 2014-01--2016-12 (3)核磁共振成像和光子上/下转换纳米探针及其活体良恶性肿瘤诊断方法, 主持, 省级, 2017-01--2018-12 (4)Er3+基纳米新结构生物探针的设计和制备及其高清晰生物成像应用研究, 主持, 市地级, 2019-07--2022-06 (5)癌症早期诊断与精准治疗一体化光开关型上转换纳米光敏剂及其应用, 参与, 国家级, 2019-01--2022-12 (6)一种新型在体实时监测血液pH值探针的构建研究, 参与, 省级, 2018-01--2019-12 (7)基于近红外二区成像的光控化学能纳米平台构建及其肿瘤早期诊治研究, 主持, 国家级, 2021-01--2024-12
研究领域
在光子动力学研究,凝聚态物质中的元激发,凝聚态中的发光动力学过程研究以及光电子材料与器件、生物体系中的光与生物分子的相互作用、荧光共振能量传递等研究领域具有坚实的理论基础和丰富的工作经验。在生物医学光子纳米材料和物理及其在肿瘤免疫检测和可视化治疗等研究方向具有研究特色和优势
近期论文
Mitochondria-Immobilized Unimolecular Fluorescent Probe for Multiplexing Imaging of Living Cancer Cells, Analytical chemiistry, 2020, 通讯作者 Polyphotosensitizer nanogels for GSH-responsive histone deacetylase inhibitors delivery and enhanced cancer photodynamic therapy, Colloids and Surfaces B: Biointerfaces, 2020, 通讯作者 Optical imaging and pH-awakening therapy of deep tissue cancer based on specific upconversion nanophotosensitizers, Biomaterials, 2020, 通讯作者 Near-infrared light-mediated and nitric oxide-supplied nanospheres for enhanced synergistic thermo-chemotherapy, Journal of Materials Chemistry B, 2019, 通讯作者 Assembly of upconversion nanophotosensitizer in vivo to achieve scatheless real-time imaging and selective photodynamic therapy, Biomaterials, 2019, 通讯作者 Near Infrared Light Sensitive Ultraviolet-Blue Nanophotoswitch for Imaging-Guided "Off-On" Therapy, ACS Nano, 2018, 通讯作者 800 nm driven NaErF4@NaLuF4 upconversion platform for multimodality imaging and photodynamic therapy, Nanoscale, 2018, 通讯作者 Near-infrared light-mediated and nitric oxide-supplied nanospheres for enhanced synergistic thermo-chemotherapy, Journal of Materials Chemistry B, 2018, 通讯作者 Bcl-2 inhibitor uploaded upconversion nanophotosensitizers to overcome the photodynamic therapy resistance of cancer through adjuvant intervention strategy, Biomaterials, 2017, 通讯作者 Precise Photodynamic Therapy of Cancer via Subcellular Dynamic Tracing of Dual-loaded Upconversion Nanophotosensitizers, Scientific Reports, 2017, 第 1 作者 Amphiphilic copolymer and TPGS mixed magnetic hybrid micelles for stepwise targeted co-delivery of DOX/TPP–DOX and image-guided chemotherapy with enhanced, RSC advances, 2017, 通讯作者