教育经历 2003.09—2007.07 兰州大学，药学院，药学专业，医学学士   2007.09—2012.07 中国科学院成都生物研究所，天然产物研究中心，药物化学，理学博士（导师：邵华武研究员） 2007.09—2008.07 中国科学技术大学化学系（理论课程学习） 工作经历 2012.07—2012.10中国科学院成都生物研究所天然产物研究中心，研究助理（项目聘用） 2012.12—2016.03比利时法语鲁汶大学有机化学和药物化学系 （合作导师： Istv n E. Mark 教授），博士后 2016.03—2019.03英国布里斯托大学化学系（合作导师：John. F. Bower 教授），博士后 2019.08—至今 中国科学院成都生物研究所，研究员

糖化学、有机合成、药物化学、不对称合成

Jiangtao Li, Zhengyan Fu, Zeen Qiao, Demeng Xie, Li Zhang, Ya-Zhou Liu, Jian Yang, Jia-Xin Yan,Xiaofeng Ma,* Controllable 1,3-bis-Functionalizaiton of 2-Nitroglycals with High Regioselectivity and Stereoselectivity Enabled by a H-Bond Catalyst, JACS Au 2024, 4, 974−984. Li Zhang, Wei Zeng, Demeng Xie, Jiangtao Li, Xiaofeng Ma,* Nickel and Chiral Phosphoric Acid Cocatalysis Enables Synthesis of C-Acyl Glycosides, Org. Lett. 2024, 26, 1332−1337. Ya-Zhou Liu, Yu Chen, Amu Wang, Zhongke Shen, Xueting Zhou, Jichao Zhang, Yinxiang Jian, Xiaofeng Ma,* Electron-donor-acceptor Complex Between Two Intermediates Enables a N-N Bond Cleavage Cascade Process to Access 2,3-Difunctionalized Pyridines, Green Chem. 2024, 26, 2280–2289. Yong-Qiang Wang,* Wei-Ting Chen, Xia Liu, Hua Zhu, Xuan Qiao, Yuzhi Wang, Xiaofeng Ma,* Development of a Safe, Efficient and Scalable Process for the Synthesis of Midazolam Hydrochloride, Org. Process Res. Dev. 2023, 27, 2374–2384. Xiaofang Hu, Zeen Qiao, Li Zhang, Jinzhong Zhao, Ya-Zhou Liu, Jiangang Zhang,* Xiaofeng Ma,* One-pot Cascade Synthesis of Dibenzothiophene-based Heterobiaryls from Dibenzothiophene-5-oxide, Org. Biomol. Chem. 2023, 21, 9123–9127. Junxiu Liang, Ya-Zhou Liu, Amu Wang, Yanchao Wu, Xiaofeng Ma*, Huijing Li*, Dearomatization of Halonaphthols via an Intermolecular [4+1] Spiroannulation with in situ Formed Aza-Ortho-Quinone Methides, Chin. J. Org. Chem. 2023, 43,3888–3899. Jian Yang, Shanqiao Wei, Jinzhong Zhao, Wei Zeng, Huawu Shao*, Xiaofeng Ma*, An Environmentally Benign Protocol for the Synthesis of Sugar 1,2-Orthoesters in Poly(ethylene glycol) Dimethyl Ether (DMPE), Carbohydr. Res. 2023, 534, 108902. Hailong Shi, Jinlian Yang, Zeen Qiao, Lingyu Li, Gang Liu, Qi Dai, Li Xu, Wei Jiao, Guolin Zhang, Fei Wang, Xiaoxia Lu*, Xiaofeng Ma*, Design, Synthesis and Structure–Activity Relationship Studies on Erianin Analogues as Pyruvate Carboxylase (PC) Inhibitors Against Hepatocellular Carcinoma Cells, Org. Biomol. Chem. 2023, 21, 7005-7017. Jian Yang, Demeng Xie, Xiaofeng Ma*, Recent Advances in Chemical Synthesis of Amino Sugars, Molecules, 2023, 28, 4724. Yinxiang Jian, Peng Liang, Xiaoyan Li, Huawu Shao*, Xiaofeng Ma*, Controllable Transformation of Indoles Using Iodine(III) Reagent, Org. Biomol. Chem. 2023, 21, 179-186. Xiaoke Zhang, Ya-Zhou Liu, Huawu Shao*, Xiaofeng Ma*, Advances in Atroposelectively De Novo Synthesis of Axially Chiral Heterobiaryl Scaffolds Molecules 2022, 27, 8517. Hailong Shi, Jian Yang, Yao Cheng, Jinlian Yang, Xiaoxia Lu*, Xiaofeng Ma*, 1, 2-trans-Stereoselective 7-O-Glycosylation of Flavonoids with Unprotected Pyranoses by Mitsunobu Reaction, Chem. Asian J. 2022, 17, e2022001. Zhongke Shen, Qin Tang, Wei Jiao, Huawu Shao*, Xiaofeng Ma*, One-Pot Synthesis of 2-C-Branched Glycosyl Triazoles by Integrating 1,2-Cyclopropanated Sugar Ring-Opening Azidation and CuAAC Reaction, J. Org. Chem. 2022, 87, 16736-16742. Amu Wang, Ya-Zhou Liu,Zhongke Shen, Zeen Qiao, Xiaofeng Ma*, Regioselective Synthesis of Pyrazolo[1,5-a]pyridine via TEMPO Mediated [3+2] Annulation-Aromatization of N-Aminopyridines and , -Unsaturated Compounds, Org. Lett. 2022, 24, 7, 1454-1459. Peng Liang, Hang Zhao, Tingting Zhou, Kaiyun Zeng, Wei Jiao, Yang Pan, Yazhou Liu, Dongmei Fang, Xiaofeng Ma*, Huawu Shao*. Rapid Oxidation Indoles into 2-Oxindoles Mediated by PIFA in Combination with n-Bu4NCl  H2O, Adv. Synth. Catal. 2021, 363, 3532-3538. Xiaofeng Ma*, Yazhou Liu, Le Du, Jingwei Zhou, Istv n E. Mark . Post-functionalization of Dibenzothiophene to Functionalized Biphenyls via a Photoinduced Thia-Baeyer-Villiger Oxidation, Nat. Commun. 2020, 11, 914. Xiaofeng Ma, Ian R. Hazelden, Thomas Langer, Rachel H. Munday, John F. Bower*. Enantioselective Aza-Heck Cyclizations of N‑(Tosyloxy)carbamates: Synthesis of Pyrrolidines and Piperidines, J. Am. Chem. Soc. 2019, 141, 3356-3360. (Highlight in Synfacts, 2019; 15, 0483). Xiaofeng Ma, Joshua J. Farndon, Tom A. Young, Natalie Fey, John F. Bower*, A Simple and Broadly Applicable C-N Bond Forming Dearomatization Protocol Enabled by Bifunctional Amino-Reagents, Angew. Chem. Int. Ed. 2017, 56, 14531-14535. (Highlight in Org. Process Res. Dev. 2017, 21, 1873-1883). Ian R. Hazelden,+ Xiaofeng Ma,+(+并列第一作者) Thomas Langer, John F. Bower*, Diverse N-Heterocyclic Ring Systems via Aza-Heck Cyclizations of N-(Pentafluorobenzoyloxy)sulfonamides, Angew. Chem. Int. Ed. 2016, 55, 11198-11202. Xiaofeng Ma,* Damien F. Dewez, Le Du, Xiya Luo, Istv n E. Mark , Kevin Lam*, Synthesis of Diketones, Ketoesters and Tetraketones by Electrochemical Oxidative Decarboxylation of Malonic Acid Derivatives: Application to the Synthesis of cis-Jasmone, J. Org. Chem. 2018, 83, 12044-12055. Xiaofeng Ma, Hodney Lubin, gnes Simon, Enik Ioja, Orsolya K kesi, gota Ap ti, Tam s I. Orb n, L szl H ja, Julianna Kardos, Istv n E. Mark *, Straightforward and Effective Synthesis of -Aminobutyric Acid Transporter Subtype 2-Selective Acyl-Substituted Azaspiro[4.5]decanes, Bioorg. Med. Chem. Lett. 2016, 26, 417-423. Xiaofeng Ma, Xiya Luo, Simon Dochain, Charlotte Mathot, Istv n E. Mark *, Electrochemical Oxidative Decarboxylation of Malonic Acid Derivatives: A Method for the Synthesis of Ketals and Ketones, Org. Lett.2015, 17, 4690-4693. (Featured on Organic Chemistry Portal, https://www.organic- chemistry. org/ abstracts /lit5/128.shtm) Xiaofeng Ma, Jichao Zhang, Qin Tang, Jun Ke, Wei Zou, Huawu Shao*, Stereospecific [3+2] Cycloaddition of 1,2-Cyclopropanated Sugars and Ketones Catalyzed by SnCl4: an Efficient Synthesis of Multi-Substituted Perhydrofuro[2,3-b]furans and Perhydrofuro[2,3-b]pyrans,Chem. Commun. 2014, 50, 3505-3508. Xiaofeng Ma, Qin Tang, Jun Ke, Jichao Zhang, Xinglong Yang, Xudong Shen, Huawu Shao*, A Neighboring Group Participation Strategy: Direct and Highly Diastereoselective Synthesisof 2-Substituted and 2,2-Bisubstituted Perhydrofuro[2,3-b]pyran Derivatives, Org. Biomol. Chem. 2014, 12, 7381-7388. Xiaofeng Ma, Qin Tang, Jun Ke, Jichao Zhang, Cong Wang, Haibo Wang, Yuxue Li, Huawu Shao*, Straightforward and Highly Diastereoselective Synthesis of 2,2-Disubstituted Perhydrofuro[2,3-b]pyran (and furan) Derivatives Promoted by BiCl3, Chem. Commun. 2013, 49, 7085-7087 (Highlight in Synfacts, 2013; 9, 1212). Xiaofeng Ma, Qin Tang, Jun Ke, Xinglong Yang, Jichao Zhang, Huawu Shao*, InCl3 Catalyzed Highly Diastereoselective [3+2] Cycloaddition of 1,2-Cyclopropanated Sugars with Aldehydes: a Straightforward Synthesis of Persubstituted Bis-Tetrahydrofurans and perhydrofuro [2,3-b]pyrans,Org. Lett. 2013, 15, 5170-5173. Xiaofeng Ma, Qin Tang, Jun Ke, Haibo Wang, Wei Zou, Huawu Shao*, A Convenient and Highly Stereoselective Method for Synthesis of Octahydropyrano[3,2-b]pyrrole Derivatives, Carbohydr. Res. 2013, 366, 55-62. Shuaibing Zhang, + Xiaofeng Ma, + (+并列第一作者) Xiaoqiong Pei, Jingyuan Liu, Huawu Shao, Zhongliu Wu, A Practical High-throughput Screening System for Feruloyl Esterases: Substrate Design and Evaluation,J. Mol. Catal.B-Enzym. 2012, 74, 36-40. Xiaofeng Ma, Qiang Tian, Qin Tang, Huawu Shao*, A Novel and Highly Stereoselective Synthesis of 2-Substituted Perhydrofuro[2,3-b]pyran Derivatives, Org. Lett. 2011, 13, 4276-4279.