中国科学技术大学教授，博士生导师。共发表100余篇有关神经发育疾病，神经递质新受体的分子克隆和药理学鉴定，神经退变性疾病的分子机制及病理，神经免疫等方面的文章(Nature Medicine, Journal of Cell Biology, Cell Molecular Cell, JAMA Psychiatry, Neuron, Proc. Natl. Acad. Sci. USA, Brain, Neurology, Journal of Neuroscience, 等重要生物医学国际学术期刊。获得多项奖项及荣誉称号包括：阿尔茲海默病领域里的“先锋奖(Zenith Award)”以及“阿尔兹海默病研究杰出贡献奖(Outstanding Contributor to Alzheimer Research)”。

脑功能及疾病（神经退行性疾病和精神疾病）的分子机制研究包括脑内基因特别表达和调控和新基因的发现 神经退行性疾病和精神疾病新治疗靶点的分子病理学鉴定以及药物发现 新型脑疾病的早期临床诊断性标记物的发现和研究

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