梁好均，教授，1963年5月生于吉林。1984年7月毕业于东北师范大学物理系；1990年12月于长春应用化学研究所获博士学位。2002年中国科学技术大学教授。1999. 12 – 2000. 8月香港中文大学化学系访问学者；2000. 12 – 2001. 9英国Loughborough 大学材料系访问学者；2003. 9 - 11美国SUNY Buffalo大学生物物理系访问学者。研究集中在高分子材料设计、制备、高分子凝聚态物理和生物物理中的理论与计算等方面。内容包括蛋白质与蛋白质、DNA、合成大分子及有机分子间相互作用；多肽、合成大分子及有机小分子药物设计；杂链大分子及蛋白质单链折叠和设计；大分子粗粒化模型建立及多尺度模拟；杂链大分子及蛋白质在熔体、溶液状态下组装及聚集；聚合物材料表面改性。先后承担国家自然科学基金、国家973计划等研究课题。在Macromolecules, J. Chem. Phys., J. Phys. Chem. B, Phys. Rev. E 等期刊杂志上发表SCI文章60余篇。2005年国家杰出青年基金获得者。The Open Chemical Physics Journal, International Journal of Polymer Science和《高分子学报》杂志编委。 2002年至今，中国科学技术大学，任高分子科学与工程系教授、博士生导师。 1998. 4 - 2001. 12, 中国科学技术大学，任高分子科学与工程系副教授。 2003. 9 - 2003. 11，纽约州立大学布法罗分校(SUNY Buffalo)生物物理系访问学者。 2000. 12 – 2001. 9，拉夫堡大学(Loughborough University)材料系访问学者。 1999. 12 – 2000. 8，香港中文大学化学系访问学者。 1990年12月于长春应用化学研究所获博士学位。 1984年7月毕业于东北师范大学物理系。 部分获奖与荣誉 王宽诚育才奖 (2003, 2012) 国家杰出青年基金 (2005) 张懋森基金-科研奖 (2021)

高分子凝聚态物理理论计算与模拟 大分子粗粒化模型建立及软物质多尺度模拟 DNA分子机器及在疾病诊断中的应用 DNA大分子组装及生物传感器、DNA-纳米金催组装 细胞基因线路改写与细胞重编程 细胞基因编辑、转录调控机制研究、CAR-T免疫治疗 细胞-细胞相互作用、细胞组装 种植材料、菌丝可降解生物材料

232. Junxiang Zhou, Miao He, Xue Yin, Yue Yu*, Dongbao Yao*, Haojun Liang*. Unexploited Performance of NLS in dCas9-VPR Mediated Transcriptional Activation. ACS CHEMICAL BIOLOGY. 2023.Accepted. 231. Wenjie Han, Zhigang Li, Yijun Guo, Kaining He, Wenqing Li, Caoling Xu, Lishuang Ge, Miao He, Xue Yin, Junxiang Zhou, Chengxu Li, Dongbao Yao, Jianqiang Bao* and Haojun Liang*. Efficient precise integration of large DNA sequences with 3′-overhang dsDNA donors using CRISPR/Cas9. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES. 2023.Accepted. 230. Dongbao Yao*, Yunhan Zhang, Xiang Zhou*, Xiaoyun Sun, Xiaoyu Liu, Junxiang Zhou, Wei Jiang, Wenqiang Hua, Haojun Liang*. Catalytic-assembly of programmable atom equivalents. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES. 2023.Accepted. 229. Yunhan Zhang, Shiyan Xiao*, Haojun Liang*. Avoiding kinetic trapping in self-assembly of DNA-functionalized gold nanoparticles by using enthalpy-mediated strategy. MACROMOLECULES. 2023.Accepted. 228. Yanqiu Du, Yunhan Zhang, Jing Jin*, Shiyan Xiao*, Haojun Liang, Wei Jiang*. Topology-Directed Self-Locking of Colloidal Suprastructures. MACROMOLECULES. 2023.56, 7, 2781–2789. 227. Shiyan Xiao*, Chengxu Li, Haojun Liang*. DNA: structure, strand displacement and reaction network. SCIENTIA SINICA CHIMICA. 2023.doi: 10.1360/SSC-2023-0006. 226. Chengxu Li, Shiyan Xiao*, Haojun Liang*. Effects of Fluorescent Pair on the Kinetics of DNA Strand Displacement Reaction[J]. CHINESE JOURNAL OF CHEMICAL PHYSICS. 2023.doi: 10.1063/1674-0068/cjcp2302015. 225. Tongwei Chen, Yunhan Zhang*, Shiyan Xiao , Dongbao Yao, Wei Jiang*, Haojun Liang*. Catalytic assembly of symmetric diblock copolymers in a thin film: A dissipative particle dynamics simulation. PHYSICAL CHEMISTRY CHEMICAL PHYSICS. 2023.25, 9779-9784. 2022 224. LI Chengxu, XIAO Shiyan, LIANG Haojun. Regulation of Gene Expression via Toehold Switch in E. coli[J]. JOURNAL OF FUNCTIONAL POLYMERS. 2022.doi: 10.14133/j.cnki.1008-9357.20221130001. 223. YIN Xue, YAO Dongbao, LIANG Haojun. Shortening Pairing of the 3' Tail of shRNA with Target mRNA Reduces the Off-target Effect[J]. JOURNAL OF FUNCTIONAL POLYMERS. 2022.doi: 10.14133/j.cnki.1008-9357.20221128002. 222. Junxiang Zhou, Xue Yin & Haojun Liang*. An Effective Platform for SARS-CoV-2 Prevention by Combining Neutralization and RNAi Technology[J]. CHINESE JOURNAL OF POLYMER SCIENCE. 2022.41 (3), 327-333. 221. Xue Yin, Dongbao Yao*, Haojun Liang*. Tuning Gene Expression by Hairpin Elements near the Start Codon of mRNA in Mammalian Cells[J]. CHINESE JOURNAL OF CHEMICAL PHYSICS. 2022.doi: 10.1063/1674-0068/cjcp2207107. 220. Jianing Zhang, Jiayu Yu, Jing Jin*, Xiang Zhou, Haojun Liang, Feng Zhou and Wei Jiang*. Bridge DNA guided Assembly of Nanoparticles to Program Chemical Reaction Networks. NANOSCALE. 2022.14, 12162-12173. 219. Tingjie Song, Xiaojing Wang, Dongbao Yao, Haojun Liang* and Yi Lu*. Identifying and Differentiating Topological G-Quadruplex Structures with DNA-encoded Plasmonic Gold Nanoparticles. ANGEWANDTE CHEMIE INTERNATIONAL EDITION. 2022.e202204201. 218. Miao He, Xiang Zhou*, Zhigang Li, Xue Yin, Wenjie Han, Junxiang Zhou, Xiaoyun Sun, Xiaoyu Liu, Dongbao Yao* and Haojun Liang*. Programmable transcriptional modulation with a structured RNA-mediated CRISPR-dCas9 complex. JOURNAL OF THE AMARICAN CHEMICAL SOCIETY. 2022.144, 12690−12697. 217. Wenjie Han, Miao He, Yunhan Zhang, Junxiang Zhou, Zhigang Li, Xiaoyu Liu, Xiaoyun Sun, Xue Yin, Dongbao Yao* and Haojun Liang*. Cadherin-dependent adhesion modulated 3D cell-assembly. JOURNAL OF MATERIALS CHEMISTRY B. 2022.10,4959-4966. 216. Bárbara B. Mendes, João Conniot, Aviram Avital, Dongbao Yao, Xingya Jiang, Xiang Zhou, Noga Sharf-Pauker, Yuling Xiao, Omer Adir, Haojun Liang*, Jinjun Shi*, Avi Schroeder* & João Conde*. Nanodelivery of nucleic acids. NATURE REVIEWS METHODS PRIMERS. 2022.2(24),1-21. PRIMEVIEWS.