中国科学技术大学生命科学学院教授，博士生导师，1997年至2006年就读于中国科学技术大学，获得理学和工学双学士学位，细胞生物学博士学位；2006至2011年在美国宾夕法尼亚大学进行博士后研究；2011年被香港大学聘为助理教授（tenure track）在李嘉诚医学院组建独立团队开展研究；2015年辞去香港大学职位，加入中国科学技术大学。致力于研究亚细胞结构动态和细胞命运可塑性调控机制，发现和命名多个重要的微管细胞骨架、线粒体调控蛋白，发表研究论文70余篇。相关的研究成果发表在《Dev Cell》、《J Cell Biol》、《PLoS Biol》、《Nature Commun》、《Redox Biol》、《Curr Biol》、《J Cell Sci》、《J Biol Chem》、《Cell Res》等期刊。任《Cellular and Molecular Life Sciences》、《Cell Biology International》副主编，中国细胞生物学会细胞结构与细胞行为分会副会长，安徽省化学生物学与新质医学重点实验室主任。 教育与科研经历 1997-2001 中国科学技术大学、生物科学、学士 1999-2001 中国科学技术大学、计算机科学和技术、学士 2001-2006 中国科学技术大学、细胞生物学、博士 2006-2011 美国宾夕法尼亚大学、博士后 2011-2015 香港大学、助理教授 2016-至今 中国科学技术大学、教授

微管细胞骨架动力学、线粒体动力学、有丝分裂及减数分裂

1) Liu L, Wu Y, Liu K, Zhu M, Guang S, Wang F, Liu X, Yao X, He J*, Fu C.*. 2024. The absence of the ribosomal protein Rpl2702 elicits the MAPK-mTOR signaling to modulate mitochondrial morphology and functions. Redox Biol. 73:103174 2) Zhu M, Fang Z, Wu Y, Dong F, Wang Y, Zheng F, Ma X, Ma S, He J, Liu X, Yao X*, Fu C.*. 2024. A KDELR-mediated ER-retrieval system modulates mitochondrial functions via the unfolded protein response in fission yeast. J Biol Chem. 300(3):105754 3) Jian Y, Jiang Y, Nie L, Dou Z, Liu X, Fu C.*. 2023. Phosphorylation of Bub1 by Mph1 promotes the Bub1 signaling at the kinetochore to ensure accurate chromosome segregation. J Biol Chem. 105559. 300(1):105559 4) Wei W, Zheng B, Zheng S, Wu D, Chu Y, Zhang S, Wang D, Ma X, Liu X, Yao X*, Fu C*. 2022. The Cdc42 GAP Rga6 promotes monopolar outgrowth of spores. J Cell Biol. 222(1):e202202064 5) He J#, Liu K#, Wu Y, Zhao C, Yan S, Chen JH, Hu L, Wang D, Zheng F, Wei W*, Fu C*. 2023. Protein palmitoylation-mediated palmitic acid sensing causes blood-testis barrier damage via inducing ER stress. PLoS Biol. 21: e3002247 6) Wu Z, Xu H, Wang P, Liu L, Cai J, Chen Y, Zhao X, You X, Liu J, Guo X, Xie T, Feng J, Zhou F, Li R, Xie Z, Xue Y*, Fu C*, Liang Y*. 2022. The entry of unclosed autophagosomes into vacuoles and its physiological relevance. PLoS Genet. 8(10):e1010431 7) Wang X, Zheng F, Yi YY, Wang GY, Hong LX, McCollum D, Fu C*, Wang Y*, Jin QW.*. 2022. Ubiquitination of CLIP-170 family protein restrains polarized growth upon DNA replication stress. Nature Commun. 13(1):5565 8) Ge X, He Z, Cao C, Xue T, Jing J, Ma R, Zhao W, Liu L, Jueraitetibaike K, Ma J, Feng Y, Qian Z, Zou Z, Chen L, Fu C*, Song N*, Yao B*. 2022. Protein palmitoylation-mediated palmitic acid sensing causes blood-testis barrier damage via inducing ER stress. Redox Biol. 54:102380 9) Zheng S, Zheng B, Liu Z, Liu X, Yao X, Wei W*, Fu C*. 2022. The Cdc42 GTPase activating protein Rga6 promotes the cortical localization of Septin. J Cell Sci. 135(4):jcs259228 10) Dong F, Zhu M, Zheng F, Fu C*. 2022. Mitochondrial fusion and fission are required for proper mitochondrial function and cell proliferation in fission yeast. FEBS J. 2022 Jan;289(1):262-278 (Cover story) 11) Rasul F, Zheng F, Dong F, He J, Liu L, Liu W, Cheema J, Wei W*, Fu C*. 2021. Emr1 regulates the number of foci of the endoplasmic reticulum-mitochondria encounter structure complex. Nature Commun. 12(1):521 12) Zhang M#, Zheng F#, Xiong Y, Shao C, Wang C, Wu M, Niu X, Dong F, Zhang X*, Fu C*, Zang J*. 2021. Centromere targeting of Mis18 requires the interaction with DNA and H2A-H2B in fission yeast. Cell Mol Life Sci. 78(1):373-384 13) Zheng F#, Dong F#, Yu S, Li T, Jian Y, Nie L, Fu C*. 2020. Klp2 and Ase1 synergize to maintain meiotic spindle stability during metaphase I. J Biol Chem. 295(38):13287-13298 14) Zheng F#, Jia B#, Dong F, Liu L, Rasul F, He J, Fu C*. 2019. Glucose starvation induces mitochondrial fragmentation depending on the dynamin GTPase Dnm1/Drp1 in fission yeast. J Biol Chem. 294(47):17725-17734 (Cover story) 15) Zhu Q, Zheng F, Liu AP, Qian J, Fu C*, Lin Y*. 2016. Shape Transformation of the Nuclear Envelope during Closed Mitosis. Biophys J. 111(10):2309-2316 16) Syrovatkina V#, Fu C#, Tran PT. 2013. Antagonistic spindle motors and MAPs regulate metaphase spindle length and chromosome segregation. Curr Biol. 23: 2423-9 (#cofirst) 17) Fu C*, Jain D, Costa J, Velve-Casquillas G, Tran PT*. 2011. Mmb1p binds mitochondria to dynamic microtubules. Curr Biol. 21:1431-39 (*corresponding) (Cover story) 18) Fu C, Ward JJ, Loiodice I, Velve-Casquillas G, Nedelec FJ, Tran PT. 2009. Phospho-regulated interaction between kinesin-6 Klp9p and microtubule bundler Ase1p promotes spindle elongation. Dev Cell 17: 257-67