教育背景： 1994.09 - 1998.06，河北大学，生物技术，学士 1999.09 - 2004.06，中国科学院水生生物研究所，遗传学，博士 工作经历： 2004.07 - 2006.11，中国科学院武汉植物园，助理研究员 / 副研究员 2006.11 - 2008.11，密西根大学分子、细胞和发育生物学系，访问学者 / 博士后 2009.02 - 至今，中国海洋大学医药学院，教授 获奖荣誉： 2009 年教育部新世纪优秀人才

发现与疾病相关新功能基因和新信号通路 Wnt 等重要信号通路调控机制解析 药物筛选模型的构建

代表性论文 1.Bo Wang, Qian Zhao, Xiaoxia Gong, Caixia Wang, Yan Bai, Hongying Wang, Jianfeng Zhou*, Xiaozhi Rong* Transmembrane anterior posterior transformation 1 (TAPT1) regulates BMP signaling and modulates the protein stability of SMAD1/5. J Biol Chem,2022 doi: 10.1016/j.jbc.2022.102684. 2.Caixia Wang, Xin Zhang, Xinyu Wang, Yanpeng Zhai, Mengjiao Li, Jun Pan, Yan Bai, Xiaozhi Rong*, Jianfeng Zhou*. Genetic deletion of hspa8 leads to selective tissue malformations in zebrafish embryonic development. J Cell Sci, 2022, 135, jcs.259734. 3.Chunxiao Sun#, Qianwen Liu#, Mudassir Shah, Qian Che, Guojian Zhang, Tianjiao Zhu, Jianfeng Zhou, Xiaozhi Rong*, Dehai Li* Talaverrucin A, heterodimeric oxaphenalenone from Antarctica sponge-derived fungus Talaromyces sp. HDN151403, inhibits Wnt/β-catenin signaling pathway. Org Lett 2022 24:3993-3997. 4.Bo Wang#, Xiaozhi Rong#*, Yumei Zhou, Yunzhang Liu, Jiqin Sun, Beibei Zhao, Bei Deng, Lei Lu, Ling Lu, Yun Li and Jianfeng Zhou*.Eukaryotic initiation factor 4A3 inhibits Wnt/β-catenin signaling and regulates axis formation in zebrafish embryos. Development, 2021, 148, dev198101. 5.Haifeng Zhang#, Xiaozhi Rong#*, Caixia Wang, Yunzhang Liu, Ling Lu, Yun Li, Chengtian Zhao, Jianfeng Zhou*. VBP1 modulates Wnt/β-catenin signaling by mediating the stability of the transcription factors TCF/LEFs. J Biol Chem, 2020, 295: 16826–16839. 6.Yonghua Sun, Bo Zhang, Lingfei Luo, De-Li Shi, Han Wang, Zongbin Cui, Honghui Huang, Ying Cao, Xiaodong Shu, Wenqing Zhang, Jianfeng Zhou, Yun Li, Jiulin Du, Qingshun Zhao, Jun Chen, Hanbing Zhong, Tao P Zhong, Li Li, Jing-Wei Xiong, Jinrong Peng, Wuhan Xiao, Jian Zhang, Jihua Yao, Zhan Yin, Xianming Mo, Gang Peng, Jun Zhu, Yan Chen, Yong Zhou, Dong Liu, Weijun Pan, Yiyue Zhang, Hua Ruan, Feng Liu*, Zuoyan Zhu*, Anming Meng*, ZAKOC Consortium. Systematic genome editing of the genes on zebrafish chromosome 1 by CRISPR/Cas9. Genome Res, 2019, 30:118-126. 7.Xiaozhi Rong, Yumei Zhou, Yunzhang Liu, Beibei Zhao, Bo Wang, Caixia Wang, Xiaoxia Gong, Peipei Tang, Ling Lu, Yun Li, Chengtian Zhao, Jianfeng Zhou*. Glutathione peroxidase 4 inhibits Wnt/β-catenin signaling and regulates dorsal organizer formation in zebrafish embryos. Development, 2017, 144: 1687-1697. 8.Yan Bai#, Xungang Tan#, Haifeng Zhang#, Chengdong Liu, Beibei Zhao, Yun Li, Ling Lu, Yunzhang Liu, JianfengZhou*. Ror2 receptor mediates Wnt11 ligand signaling and affects convergence and extension movements in zebrafish. J Biol Chem, 2014, 289: 20664-20676.