1965年出生，江苏扬州人 1987年7月获山东海洋学院学士学位 1993年7月获青岛海洋大学硕士学位 1999年7月获青岛海洋大学博士学位 1987.7–1993.6，山东海洋学院助教 1993.6–1995.12，青岛海洋大学讲师 1995.12至今，中国海洋大学教授 2004.2至今，中国海洋大学博士生导师 1999.12–2002.2，德国杜塞尔多夫大学药物生物学研究所高级访问学者

海洋药物化学与药物生物学。围绕海洋药用生物资源，开展海洋药用生物多样性、代谢及其调控，海洋天然产物化学及其生物学功能，海洋药物先导化合物发现与优化等研究。重点开展典型海洋环境中药用生物 (海洋无脊椎动物及微生物) 活性次级代谢产物研究，针对癌症、感染性疾病、神经退行性疾病等严重威胁人类健康的重大疾病，筛选发现活性海洋天然产物，通过设计、优化、合成靶向性发现药物先导化合物。

中华医学会航海医学分会海洋生物工程专业委员会副主任委员 中国生物化学与分子生物学会海洋生物化学与分子生物学会副理事长 中国药学会海洋药物专业委员会委员 中国海洋湖沼学会理事 Marine Drugs杂志编委 Marine Life Science & Technology杂志编委

Jing-Shuai Wu, Guang-Shan Yao, Xiao-Hui Shi, Saif Ur Rehman, Ying Xu, Xiu-Mei Fu, Xiu-Li Zhang, Yang Liu*, Chang-Yun Wang*. Epigenetic agents trigger the production of bioactive nucleoside derivatives and bisabolane sesquiterpenes from the marine-derived fungus Aspergillus versicolor.Front. Microbiol., 2020, 11: 85. doi: 10.3389/fmicb.2020.00085 Meng-Qi Zhang, Xia Ren,Qing Zhao, Shi-Jun Yue, Xiu-Mei Fu, Xin Li, Kai-Xian Chen, Yue-Wei Guo, Chang-Lun Shao*, Chang-Yun Wang*. Hepatoprotective effects of total phenylethanoid glycosides from Acanthus ilicifolius L.against carbon tetrachloride-induced hepatotoxicity. J. Ethnopharmacol. 2020, 225, doi: 10.1016/j.jep.2020.112795 Xue-Mei Hou, Yue-Ying Li, Yun-Wei Shi, Yao-Wei Fang, Rong Chao, Yu-Cheng Gu, Chang-Yun Wang*, Chang-Lun Shao*. Integrating molecular networking and 1H NMR to target the isolation of chrysogeamides from a library of marine-derived Penicillium fungi. J. Org. Chem.,2019, 84, 1228-1237. Meng-Qi Zhang, Kai-Xia Xu, Ying Xue, Fei Cao, Lu-Jia Yang, Xue-Mei Hou, Chang-Yun Wang*, Chang-Lun Shao*. Sordarin diterpene glycosides with an unusual 1,3-dioxolan-4-one ring from the zoanthid-derived fungus Curvularia hawaiiensis TA26-15. J. Nat. Prod., 2019, 82, 2477-2482. Qing Zhao#, Xia Ren#, Min Chen, Shi-Jun Yue, Meng-Qi Zhang, Kai-Xian Chen, Yue-Wei Guo, Chang-Lun Shao*, Chang-Yun Wang*. Effects of traditional Chinese medicine formula Le-Cao-Shi on hepatitis B: in vivo and in vitro studies. J. Ethnopharmacol.,2019, 244, 112132; doi.org/10.1016/j.jep.2019.112132. Lu Liu, Zheng Zhang*, Chang-Lun Shao, Chang-Yun Wang*. Analysis of the sequences, structures and functions of product-releasing enzyme domains in fungal polyketide synthases. Front. Microbiol., 2017, 8:1685. doi: 10.3389/fmicb.2017.01685. Yan-Lai Jia#, Mei-Yan Wei#, Hai-Yan Chen, Fei-Fei Guan, Chang-Yun Wang*, Chang-Lun Shao*. (+)- and (−)-Pestaloxazine A, a pair of antiviral enantiomeric alkaloid dimers with a symmetric spiro[oxazinane-piperazinedione] skeleton from Pestalotiopsis sp.. Org. Lett., 2015, 17: 4216−4219. Fei Cao, Chang-Lun Shao, Min Chen, Meng-Qi Zhang, Kai-Xia Xu, Hong Meng,* Chang-Yun Wang*. Antiviral C-25 epimers of 26-acetoxy steroids from the South China Sea gorgonian Echinogorgia rebekka. J. Nat. Prod., 2014, 77, 1488−1493. Kai-Lin Yang, Mei-Yan Wei, Chang-Lun Shao*, Xiu-Mei Fu, Zhi-Yong Guo, Ru-Fang Xu, Cai-Juan Zheng, Zhi-Gang She*, Yong-Cheng Lin, Chang-Yun Wang*. Antibacterial anthraquinone derivatives from a sea anemone-derived fungus Nigrospora sp. J. Nat. Prod., 2012, 75: 935–941. Chang-Lun Shao, Hui-Xian Wu, Chang-Yun Wang*, Qing-Ai Liu, Ying Xu, Mei-Yan Wei, Pei-Yuan Qian, Yu-Cheng Gu, Cai-Juan Zheng, Zhi-Gang She*, Yong-Cheng Lin. Potent antifouling resorcylic acid lactones from the gorgonian-derived fungus Cochliobolus lunatus. J. Nat. Prod., 2011, 74: 629–633.