学习/工作经历 1987-1991：中国海洋大学，海水养殖专业，农学学士 1995-1999：中国海洋大学，水产养殖专业，硕士 2001-2005：中国海洋大学，水产养殖专业，博士 1991.7~至今：中国海洋大学，水产学院，讲师、副教授、教授 2011-2012：美国加州大学Davis分校，兽医学院，访问学者

水产动物病害与免疫学

1. ZhangHH,ShengXZ*,TangXQ,XingJ,ChiHandZhanWB. Transcriptomeanalysisrevealsmolecularmechanismsoflymphocystisformationcausedbylymphocystisdiseasevirusinfectioninflounder(Paralichthysolivaceus). Front.Immunol.2023,14:1268851 2. YingqinLiu,XiuzhenSheng*,XiaoqianTang,JingXing,HengChi,WenbinZhan. Genome-wideidentification,phylogeneticrelationshipsandexpressionpatternsoftheNOD-likereceptor(NLR)genefamilyinflounder(Paralichthysolivaceus). FishandShellfishImmunology,2023,141:109083. 3. Sheng,Xiuzhen;Zhang,Honghua;Liu,Min;Tang,Xiaoqian;Xing,Jing;Chi,Heng;Zhan,Wenbin. DevelopmentandEvaluationofRecombinantB-CellMulti-EpitopesofPDHA1andGAPDHasSubunitVaccinesagainstStreptococcusiniaeInfectioninFlounder(Paralichthysolivaceus). VACCINES,2023,11:624. 4. Sheng,X.Z.;Zeng,J.;Zhong,Y.;Tang,X.Q.;Xing,J.;Chi,H.;Zhan,W.B. PeripheralBloodB-LymphocytesAreInvolvedinLymphocystisDiseaseVirusInfectioninFlounder(Paralichthysolivaceus)viaCellularReceptor-MediatedMechanism. Int.J.Mol.Sci.2022,23,9225 5. ShengXZ,GuoY,ZhuH,ChaiBH,TangXQ,XingJ,ChiHandZhanWB. TransepithelialSecretionofMucosalIgMMediatedbyPolymericImmunoglobulinReceptorofFlounder(Paralichthysolivaceus):In-VivoandIn-VitroEvidence. Front.Immunol.2022,13:868753 6. ChengchengLiang,XiuzhenSheng*,XiaoqianTang,JingXing,HengChi,WenbinZhan. StructuralCharacteristicsandMucosalImmuneResponseoftheInterbranchialLymphoidTissueintheGillsofFlounder(Paralichthysolivaceus). Fish&ShellfishImmunology,2022,123:388-398. 7. XiuzhenSheng,YuanGuo,QianTang,XiaoqianTang,JingXing,HengChi,WenbinZhan*. Upregulationofpolymericimmunoglobulinreceptorexpressioninflounder(Paralichthysolivaceus)gillcellsbycytokinetumornecrosisfactor-αviaactivatingPI3KandNF-κBsignalingpathways. MolecularImmunology135(2021)170–182 8. Sheng,X.Z;Zhong,Y.;Zeng,J.;Tang,X.Q;Xing,J.;Chi,H.;Zhan,W.B. LymphocystisDiseaseVirus(Iridoviridae)EntersFlounder(Paralichthysolivaceus)GillCellsviaaCaveolae-MediatedEndocytosisMechanismFacilitatedbyViralReceptors. Int.J.Mol.Sci.2020,21,4722. 9. YingZhong,XiaoqianTang,XiuzhenSheng*,JingXing,WenbinZhan. Voltage-dependentanionchannelprotein2(VDAC2)andreceptorofactivatedproteinCkinase1(RACK1)actasfunctionalreceptorsforlymphocystisdiseasevirusinfection. JournalofVirology,2019,93(12):e00122-19. 10. XZSheng,BHChai,ZFWang,XQTang,JXing,WBZhan. PolymericimmunoglobulinreceptorandmucosalIgMresponseselicitedbyimmersionandinjectionvaccinationwithinactivatedVibrioanguillaruminflounder(Paralichthysolivaceus). Aquaculture,2019,505:1-11. 11. SusuLiu,YangDu,XiuzhenSheng∗,XiaoqianTang,JingXing,WebinZhan. Molecularcloningofpolymericimmunoglobulinreceptor-like(pIgRL)inflounder(Paralichthysolivaceus)anditsexpressioninresponsetoimmunizationwithinactivatedVibrioanguillarum. Fish&ShellfishImmonology.2019,87:524-533. 12. ShengXZ,QianXY,TangXQ,XingJandZhanWB(2018) PolymericImmunoglobulinReceptorMediatesImmuneExcretionofMucosalIgM–AntigenComplexesAcrossIntestinalEpitheliuminFlounder(Paralichthysolivaceus). FrontiersImmunology.2018,9:1562