刘士凯 照片

刘士凯

博士 教授 博士生导师

所属大学: 中国海洋大学

所属学院: 水产学院

邮箱:
liushk@ouc.edu.cn

个人主页:
https://scxy.ouc.edu.cn/2023/1117/c20709a448022/page.htm

个人简介

学习/工作经历 2014年获美国奥本大学博士学位,2014-2017美国奥本大学从事博士后研究工作,2017年获聘中国海洋大学“青年英才工程”第一层次教授、博士生导师。 科研/教学情况 从事水产动物基因组学、生物信息学、分子遗传育种等领域的教学与科研工作。在水产动物基因组、转录组测序分析、分子标记开发、高密度芯片构建、重要经济性状精细遗传解析和基因组选择育种等领域系统开展工作。目前,已在国际知名学术刊物发表SCI论文100余篇。参编学术专著4部。 与国外多所高校、研究所保持密切合作关系,硕士期间表现优异者,有机会推荐至美国雪城大学(Syracuse University)、奥本大学(AuburnUniversity)、马里兰大学(UniversityofMaryland)等高校攻读博士学位或进行联合培养。主持科研项目主持国家自然基金面上项目、青年基金、中央高校基本科研业务费等,累计经费260余万元。

研究领域

1.水产动物基因组学、进化发育基因组生物学2.牡蛎分子遗传学、基因组辅助育种技术3.牡蛎高产抗病抗逆分子育种

水产动物基因组学、生物信息学、分子遗传育种

学术兼职

目前担任国际知名杂志MarineBiotechnology、Molecular Biology Reports编委(EditorialBoard),FrontiersinGenetics副主编(AssociateEditor)及十多个领域知名学术刊物审稿人。

近期论文

1) Mokrani A, Liu S#. Harnessing CRISPR/Cas9 system to improve economic traits in aquaculture species. Aquaculture, 2024, 579:740279. 2) Tan Y, Li Y, Ren Li, Fu H, Li Q, Liu S#. Integrative Proteome and Metabolome Analyses Reveal Molecular Basis Underlying Growth and Nutrient Composition in the Pacific Oyster, Crassostrea gigas. Journal of Proteomics, 2024, 290:105021. 3) Bai Y*, Liu S*, Hu Y, Yu H, Kong L, Xu C, Li Q. Multi-omic insights into the formation and evolution of a novel shell microstructure in oysters. BMC Biology, 2023, 21:204. 4) Li Y, Mokrani A, Fu H, Shi C, Li Q, Liu S#. Development of Nanopore sequencing-based full-length transcriptome database toward functional genome annotation of the Pacific oyster, Crassostrea gigas. Genomics, 2023, 115(5):110697. 5) Li Y, Yang B, Shi C, Yan Y, Ren L, Mokrani A, Li Q, Liu S#. Integrated analysis of mRNAs and lncRNAs reveals candidate marker genes and potential hub lncRNAs associated with growth regulation of the Pacific oyster, Crassostrea gigas. BMC Genomics, 2023, 24:453. 6) Li Y, Tan Y, Ren L, Li Q, Liu S#. Structural and expression analysis of the dopamine receptors reveals their crucial roles in regulating the insulin signaling pathway in oysters. International Journal of Biological Macromolecules, 2023, 247:125703. 7) Fu H, Li Y, Tian J, Yang B, Li Y, Li Q, Liu S#. Contribution of HIF-1α to Heat Shock Response by Transcriptional Regulation of HSF1/HSP70 Signaling Pathway in Pacific Oyster, Crassostrea gigas. Marine Biotechnology, doi: 10.1007/s10126-023-10231-6. 8) Waldbieser G*, Liu S*, Yuan Z*, Older C, Gao D, Shi C, Bosworth B, Li N, Bao L, Kirby M, Jin Y, Wood M, Scheffler B, Simpson S, Youngblood R, Duke M, Ballard L, Phillippy A, Koren S, Liu Z. Reference genomes of channel catfish and blue catfish reveal multiple pericentric chromosome inversions. BMC Biology, 2023, 21(1):67. 9) Wu D, Yang B, Li Q, Liu S#. Estimation of genetic parameters for female 3reproduction traits in the Pacific oyster, Crassostrea gigas. Aquaculture, 2023, 569, 739387. 10) Li X, Shi C, Yang B, Li Q, Liu S#. High temperature aggravates mortalities of oysters infected with Vibrio: a perspective from homeostasis of digestive microbiota and immune response. Aquaculture, 2023, 568:739309. 11) Wang K, Yang B, Li Q, Liu S#. Systematic evaluation of genomic prediction algorithms for genomic prediction and breeding of aquatic animals. Genes, 2022, 13(12), 2247. 12) Fu H, Tian J, Shi C, Li Q, Liu S#. Ecological significance of G protein-coupled receptors in the Pacific oyster (Crassostrea gigas): pervasive gene duplication and distinct transcriptional response to marine environmental stresses. Marine Pollution Bulletin, 2022, 185, 114269. 13) Li F, Fan M, Wang S, Gu Z, Wang A, Liu C, Yang Y#, Liu S#. The complete mitochondrial genome of Hyotissa hyotis(Bivalvia: Gryphaeidae) reveals a unique gene order within Ostreoidea. Fishes, 2022, 7(6), 317. 14) Tan C, Shi C, Li Y, Teng W, Li Y, Fu H, Ren L, Yu H, Li Q, Liu S#. Comparative methylome analysis reveals epigenetic signatures associated with growth and shell color in the Pacific oyster, Crassostrea gigas. Marine Biotechnology, 2022, 24, 911-926. 15) Somrup S, Sangsawang A, McMillan N, Winitchai S, Inthoncharoen J, Liu S#, Muangmai N#. Pinctada phuketensissp. nov. (Bivalvia, Ostreida, Margaritidae), a new pearl oyster species from Phuket, western coast of Thailand. ZooKeys, 2022, 1119:181-195. 16) Wang W, Yang Y, Tan S, Zhou T, Liu Y, Tian C, Bao L, Xing D, Su B, Wang J, Zhang Y, Liu S, Shi H, Gao D, Dunham R, Liu Z. Genomic imprinting-like monoallelic paternal expression determines sex of channel catfish. Science advances, 2022, 8(51):eadc8786. 17) Jang D*, Liu Q*, Sun J*, Liu S*, Fan G*, Wang L, Zhang Y, SeimI, An S, Liu X, Li Q, Zheng X. The gold-ringed octopus (Amphioctopus fangsiao) genome and cerebral single-nucleus transcriptomes provide insights into the evolution of karyotype and neural novelties. BMC Biology, 2022, 20(1):289. 18) He Y, Li X, Shi C, Li Y, Li Q, Liu S#. Transcriptome profiling of the Pacific oyster (Crassostrea gigas) suggests distinct host immune strategy in response to Vibrio alginoticusinfection. Aquaculture, 2022, 560:738563. 19) Li X, Yang B, Shi C, Wang H, Yu R, Li Q, Liu S#. Synergistic interaction of low salinity stress with Vibrio infection causes mass mortalities in the oyster by inducing host microflora imbalance and immune dysregulation. Frontiers in Immunology, 2022, 13:859975. 20) Yang B, Zhai S, Zhang F, Wang H, Ren L, Li Y, Li Q, Liu S#. Genome-wide association study toward efficient selection breeding of resistance to Vibrio alginolyticusin Pacific oyster, Crassostrea gigas. Aquaculture, 2022, 548:737592. 21) Li Y, Ren L, Fu H, Yang B, Tian J, Li Q, Liu Z, Liu S#. Crosstalk between dopamine and insulin signaling in growth control of the oyster. General and 4Comparative Endocrinology, 2021, 313:113895. 22) Jiao Z, Tian Y, Hu B, Li Q, Liu S#. Genome structural variation landscape and its selection signatures in the fast-growing strains of the Pacific oyster, Crassostrea gigas. Marine Biotechnology, 2021, 23:736-748. 23) Hu B, Tian Y, Li Q#, Liu S#. Genomic signatures of artificial selection in the Pacific oyster, Crassostrea gigas. Evolutionary Applications, 2022, 15(4):618-630. 24) Tian J, Li Y, Fu H, Ren L, He Y, Zhai S, Yang B, Li Q, Liu N, Liu S#. Physiological role of CYP17A1-like in cadmium detoxification and its transcriptional regulation in the Pacific oyster, Crassostrea gigas. Science of the Total Environment, 2021, 796:149039. 25) Li Y, Fu H, Zhang F, Ren L, Tian J, Li Q, Liu S#. Insulin-Like Peptide Receptor-Mediated Signaling Pathways Orchestrate Regulation of Growth in the Pacific Oyster (Crassostrea gigas), as Revealed by Gene Expression Profiles. International Journal of Molecular Sciences, 2021, 22:5259. 26) Ren L, Li Y, Fu H, Zhang F, Yang B, Tan C, Li Q, Liu S#. A regulatory variant of tryptophan hydroxylase gene modulates transcription activity and biases growth rate in the Pacific oyster, Crassostrea gigas. Aquaculture, 2021, 542: 736906. 27) Fu H, Jiao Z, Li Y, Tiang J, Ren L, Zhang F, Li Q, Liu S#. Transient Receptor Potential (TRP) Channels in the Pacific Oyster (Crassostrea gigas): Genome-Wide Identification and Expression Profiling after Heat Stress between C. gigasand C. angulata. International Journal of Molecular Sciences, 2021, 22(6):3222. 28) Wang H, Yang B, Li X, Li Q, Liu S#. Screening of bacterial pathogens associated with mass summer mortality of the Pacific Oyster, Crassostrea gigas, in China. Aquaculture Reports, 2021, 20:100672 29) Yang B, Zhai S, Li X, Li Q, Shan H, Liu S#. Identification of Vibrio alginolyticusas a causative pathogen associated with mass summer mortality of the Pacific Oyster (Crassostrea gigas) in China. Aquaculture, 2021, 535: 736363. 30) Zhai S, Yang B, Zhang F, Li Q, Liu S#. Estimation of genetic parameters for resistance to Vibrio alginolyticusinfection in the Pacific oyster (Crassostrea gigas). Aquaculture, 2021, 736545.Doi: j.aquaculture.2021.736545 31) Tian J, Jiao Z, Fu H, Qi L, Li Q, Liu N, Liu S#. Identification of cytochrome P450s and their expression profiles following cadmium exposure in the Pacific oyster, Crassostrea gigas. Aquaculture Reports, 2021, 19:100582. 32) Li Y, Fu H, Zhang F, Ren L, Tiang J, Li Q, Liu S#. Identification, characterization, and expression profiles of insulin-like peptides suggest their critical roles in growth regulation of the Pacific oyster, Crassostrea gigas. Gene, 2021, 769: 145244.