学习经历 2002.9-2006.6本科中国药科大学制药工程 2008.9-2011.6硕士研究生扬州大学微生物 2011.9-2014.6博士研究生扬州大学預防兽医学 工作简历 2014.8-扬州大学兽医学院实验师

细菌群体感应系统 畜禽病原微生物

群体感应I型系统在禽致病性大肠杆菌致病进程中的功能研究(31502075)，国家自然基金青年基金，主持人。 禽致病性大肠杆菌群体感应I型系统致病功能探析(SBK2O15O43351),省青年基金，主持人。 犬恶性肿瘤自体免疫细胞治疗与瘤内注射治疗技术(2016YTO0501010),国家十三五重点研发计划“宠物疾病诊疗与防控新技术研究”子课题，主持人。

YangYang,YunLijQiumeiShi,ZhiqiangZhang,TongleiWu3andGuoqiangZhu5Effect ofLow-ConcentrationofCopperonVirulenceFactorsofaPathogenicEscherichiaColi Strain,Newpubli,2016,1-4. YangYang,MingxuZhou,HuayanHou,JunZhu,FenghuaYao,XinjunZhang’XiaofangZhu, PhilipR,Hardv/idge,andGuoqiangZhu,Quorum-sensinggeneluxSregulatesflagella expressionandShiga~liketoxinproductioninF18abEscherichiacoli.CanJMicrobiol, 2014,60(6)：355-61. YangYang,FenghuaYao,MingxuZhou,JunZhu,XinjunZhang,WenbinBao,ShenglongWu3PhilipR・HardwidgeandGuoqiangZhu,F18abEscherichiacoliflagellaexpressionis regulatedbyacyl~homoserinelactoneandcontributestobacterialvirulence. VeterinaryMicrobiology,2013,165(3~4)：378-383. HassanHusseinMusa,WeijuanZhang,JingLv,XiaoliDuan,YangYang,ChunhongZhu, HuifangLi>，KuanweiChen,XiaMeng,andGuoqiangZhu,ThemolecularadjuvantmC3d enhancestheimmunogenicityofFimAfromtypeIfimbriaeofSalmonellaenterica serovarEnteritidis,JMicrobiolImmunolInfect,2014,47(1):57-62. MingxuZhou5YangYang,PanlinChen,HuijieHu,PhilipR・HardwidgeandGuoqiangZhu, Morethanalocomotiveorganelle：flagellainEscherichiacoli,ApplMicrobiolBiotechnol,2015,99(21):8883-90. MingxuZhoUjZhiyanGuo,YangYang,QiangdeDuan,QiZhang,FenghuaYao,JunZhu,XinjunZhang’PhilipR.HardwidgeandGuoqiangZhu,FlagellinandF4fimbriaehaveoppositeeffectsonbiofilmformationandquorumsensinginF4ac+enterotoxigenicEscherichiacoli.VetMicrobiol,2014,168(1):148-53. MingxuZhou,QiangdeDuan,YinchauLi,YangYang,PhilipR.HardwidgeandGuoqiang Zhu,Membranecholesterolplaysanimportantroleinenteropathogenadhesionandthe activationofinnateimmunityviaflagellinTLR5signaling.ArchivesofMicrobiology,2015,197(6):797-803. QiangdeDuan,MingxuZhou,XiaofangZhu3WenbinBao,ShenglongWu,XiaosaiRuan,WeipingZhang,YangYang,JunZhuandGuoqiangZhu,TheflagellaofF18abEscherichia coliisavirulencefactorthatcontributestoinfectioninaIPEC-J2cellmodelinvitro.VetMicrobiol,2012,160(1~2):132-40. QiangdeDuan,MingxuZhou,XxiaofangZhu,YangYang,JunZhu,WenbinBao,Shenglong Wu^，XiaosaiRuan,WeipingZhangandGuoqiangZhu,FlagellafromF18+Escherichiacoliplayaroleinadhesiontopigepithelialcelllines.MicrobPathog,2013,55:32-8. 羊扬,厚华艳，郁磊，朱国强.大肠杆菌K99菌毛fm操纵子的克隆、表达及活性.微生物学报,2012,(12):1524-1530. 张彬彬，羊扬，刘云，朱国强.I型群体感应系统对禽致病性大肠杆菌生物被膜形成的调控机制研究.中国家2015,(24):19-23.