个人简历

1988年获四川大学学士；

1996年获UniversityofMiami博士学位；

1997-1999年，UniversityofMiami和GenentechInc.博士后；

2003-2016年，中国科学院遗传与发育生物学研究所，研究员

2016年，云南大学生命科学院副院长、生命科学研究中心副主任、教授（二级）

我们实验室对发育生物学中的重要问题感兴趣，目前主要研究方向:1）早期胚胎发育的调控（如：原始生殖细胞发生）；2）小鼠细胞谱系建立和维持。实验用模式动物包括斑马鱼，非洲爪蛙，和小鼠。我们在研究中广泛运用遗传学，细胞生物学，生物化学的方法

Zhu,D.,Gong,X.,Miao,L.,Fang,J.Zhang,J*.(2017)EfficientInductionofSyncytiotrophoblastLayerIICellsfromTrophoblastStemCellsbyCanonicalWntSignalingActivation.StemCellReports.9(6):2034-2049.

2.MiaoL,YuanY,ChengF,FangJ,ZhouF,MaW,JiangY,HuangX,WangY,ShanL,ChenD,ZhangJ*.(2017)TranslationrepressionbymaternalRNAbindingproteinZar1isessentialforearlyoogenesisinzebrafish.Development144(1):128-138.

3.ChengF,MiaoL,WuQ,GongX,XiongJ*,ZhangJ*.(2016)Vinculinbdeficiencycausesepicardialhyperplasiaandcoronaryvesseldisorganizationinzebrafish.Development.143(19):3522-3531

4.FangJ,WangH,MiaoL,KuangX,MaW,WangC,ZhangJ*,XiaG*.(2016)InvolvementofProteinAcyltransferaseZDHHC3inMaintainingOocyteMeioticArrestinXenopuslaevis.BiolReprod.95(3):67

5.MaWR,ZhangJ*.(2015)Jag1bisessentialforpatterninginnerearsensorycristaebyregulatinganteriormorphogenetictissueseparationandpreventingposteriorcelldeath.Development.142(4):763-73.

6.SuW,FangJ,ChengF,LiuC,ZhouF,ZhangJ*.(2013)RNF2/Ring1bnegativelyregulatesp53expressioninselectivecancercelltypestopromotetumordevelopment.ProcNatlAcadSciUSA.110(5):1720-5.

7.LiuC,MaW,SuW,ZhangJ*.(2012)Prdm14actsupstreamofislet2transcriptiontoregulateaxongrowthofprimarymotoneuronsinzebrafish.Development.139(24):4591-600.

8.WangHW,FangJS,KuangX,MiaoLY,WangC,XiaGL,KingML,ZhangJ*.(2012)Activityoflong-chainacyl-CoAsynthetaseisrequiredformaintainingmeioticarrestinXenopuslaevis.Biol.Reprod.87(3):74.

9.XuS,ChengF,LiangJ,WuW,ZhangJ*.(2012)MaternalxNorrin,aCanonicalWntSignalingAgonistandTGF-bAntagonist,ControlsEarlyNeuroectodermSpecificationinXenopus.PLOSBiol.10(3):e1001286.doi:10.1371/journal.pbio.1001286

10.ZhangL,ZhengS,WuH,WuY,LiuS,FanM,ZhangJ*.(2009)IdentificationofBLyS(Blymphocytestimulator),anon-myelin-associatedprotein,asafunctionalligandforNogo-66receptor.J.Neurosci.29(19):6348-52.