个人简介
学历 2005-2011 博士,细胞生物发生学,韩国高丽医科大学,预防医学 2001-2004 硕士,药学,韩国釜山国立大学,药学院 1997-2001 学士,药学,延边大学医学院 工作经历 2013-2014 博士后,美国明尼苏达大学,Masonic cancer center 2011-2013 博士后,韩国化学研究院 2009-2011 高级研究员,韩国化学研究院 2008-2009 研究员,韩国OSCOTEC Inc,天安本部新药开发研究所 2006-2007 研究助力,韩国梨花女子大学,药学院
研究领域
毒理学,药物筛选
近期论文
1) Zhi Zheng, So Hee Im, Byung Hoi Lee, Hyewon Seo, Myung Ae Bae, Sung-Hoon Ahn*. In vitro permeability analysis, pharmacokinetics and brain uptake of WAY-100635 and FCWAY in rats using liquid chromatography electrospray ionization tandem mass spectrometry, Archives of Pharmacal Research, Accepted No. ARPR-D-13-00328R1, Mar.13,2014
2) Hyewon Seo, Sung Heum Choi, Eun-Young Kwak, Zhi Zheng, Hyun Jung Kwak, Jin Hee Ahn, Yong-Moon Lee, Sung-Hoon Ahn, Myung Ae Bae, Jin Sook Song, Determination of a novel diacylglycerol acyltransferase 1 inhibitor, 2-[4-(4-{5-[2-phenyl-5-(trifluoromethyl) oxazole-4-carboxamido]-1H-benzo[d]imidazol-2-yl} phenyl) cyclohexyl] acetic acid (KR-69232) in rat plasma using liquid chromatography–tandem mass spectrometry and its application to a pharmacokinetic study, Biomedical Chromatography, Oct 14, 2013
3) Zhi Zheng, Jin Sook Song, Byung Hoi Lee, Sung-Hoon Ahn, Jin-Hee Ahn, JaeChun Woo, Ji-Young Park, Dae Seok Yoo, Myung Ae Bae, Determination of 2-(3-benzoyl)-4-hydroxy-1,1-dioxo-2H-1,2-benzothiazine-2-yl-1-phenylethanone (KR-66344) by liquid chromatography-tandem mass spectrometry, Journal of Chromatographic Science, First published online, May 14, 2013.
4) Zhi Zheng, Byung-Hoi Lee, Jae Yong Choi, Young Hoon Ryu, Myung-Ae Bae, Sung-Hoon Ahn, Determination of 5-HT receptor antagonists, MEFWAY and MPPF using liquid chromatography electrospray ionization tandem mass spectrometry in rat plasma and brain tissue, Journal of Chromatography B, Available online 26 November 2012.
5) Sohee Phark, So-Young Park, Seonyoung Choi, Zhi Zheng, Eunkyung Cho, Min Lee, Ji-Youn Lim, Jong Bok Seo, Nam Hee Won, Woon-Won Jung, Donggeun Sul, Toxicological biomarkers of 2,3,4,7,8-pentachlorodibenzofuran in proteins secreted by HepG2 cells, Proteins & proteomics, 2012,
6) Zheng Z, Park SY, Lee M, Phark S, Won NH, Kang HS, Sul D, Effects of benzo(a)pyrene on the expression of heat shock proteins, pro-inflammatory cytokines and antioxidant enzymes in hepatic tumors induced by rat hepatoma N1-S1 cells, JKMS, 2011, 222-30.
7) Park SY, Phark S, Lee M, Zheng Z, Choi S, Won NH, Jung WW, Sul D, Evaluation of plasma carcinogenic markers in rat hepatic tumors models induced by rat hepatoma N1-S1 cells and benzo(a)pyrene, Arch pharm Res, 2010, 247-55.
8) Choi S, Park SY, Jeong J, Cho E, Phark S, Lee M, Kwak D, Lim JY, Jung WW, Sul D, Identification of toxicological biomarkers of di(2-ethyhexyl)phthalate in proteins secreted by HepG2 cells using proteomic analysis, 2010, Proteomics, 1831-46.
9) Jung WW, Phark S, Oh S, Khim JY, Lee J, Nam MH, Seo JB, Park SY, Jo E, Choi S, Zheng Z, Lee JY, Lee M, Lee E, Sul D, Analysis of low molecular weight plasma proteins using ultrafiltration and large gel two-dimensional electrophoresis, Proteomics. 2009, 1827-40.
10) Woo S, Jung J, Lee C, Kwon Y, Na Y., Biooranic&Medicinal Chemistry Letters, Synthesis of New xanthone analogues and their biological activity test-cytotoxicity, topoisomerase Ⅱ inhibition and DNA cross-linking study, Biooranic&Medicinal Chemistry Letters. 2007, 1163-6.
11) 全姬善, 崔京浩*, 郑智, 李凤龙. 朴美香, 海藻酸微囊的制备及评价, ,中国新药杂志, 2005, 14(12):1435-1437.