胡雨来 照片

胡雨来

教授,博士导师

所属大学: 西北师范大学

所属学院: 化学化工学院

研究领域

主要从事有机合成研究,研究领域为: 1)不对称合成:主要开展新型手性配体的设计与合成,探索新的不对称反应,并将其用于手性药物的合成。2)有机氟化学:主要开展有机氟化新方法的研究,不对称氟化及三氟甲基化反应研究。3)有机合成方法学:探索新型的有机反应,特别是金属有机试剂参与的新反应,过渡金属催化剂催化下的反应。4)药物合成新工艺研究:主要探索手性药物及氟化药物合成中的新反应,新工艺。

近期论文

Teng Niu, Weiming Zhang, Danfeng Huang*, Changming Xu, Haifeng Wang and Yulai Hu*, A powerful reagent for synthesis of Weinreb amides directly from carboxylic acids , Org. Lett., 2009, 11(19), 4474-4477

Claire L. Morris, Yulai Hu, Geoff D. Head, Lynda J. Brown†, William G. Whittingham and Richard C. D. Brown,Oxidative Cyclization Reactions of Trienes and Dienynes: Total Synthesis of Membrarollin,J. Org. Chem., 2009, 74 (3), pp 981?988

Lynda J Brown, Denis R. Bouvet, Sue Champion, Alex M. Gibson, Yulai Hu, Alex Jackson, Imtiaz Khan, Nianchun Ma, Nicholas Millot, Harry Wadsworth and Richard C. D. Brown, A Solid-Phase Route to 18F-Labeled Tracers, Exemplified by the Synthesis of [18F]2-Fluoro-2-deoxy-D-glucose, Angew. Chem. Int. Ed., 2007, 46, 941

Yulai Hu, Alex R. L. Cecil, Xavier Frank, Christophe Gleye, Bruno Figadère and Richard C. D. Brown, Natural cis-Solamin is a mixture of two tetra-epimeric diastereoisomers: Biosynthetic implications for annonaceous acetogenins., Org. Biomol. Chem., 2006, 4, 1217-1219

Yulai Hu, Richard Brown, A Metal-Oxo Mediated Approach to the Synthesis of 21,22-Diepi-membrarollin, Chem. Commun. 2005, 5636-5637

Alex R.L.Cecil, Yulai Hu, Maria J. Vicient, Ruth Dunncan, Richard C. D. Brown, Total synthesis and preliminary biological evaluation of cis-Solamin isomers, J. Org. Chem., 2004, 69, 3368-3374

R.B. Bhunnoo, Yulai Hu, D. Laine, R.C.D. Brown, Asymmetric dihydroxylation of olefins in the presence of a chiral phase transfer agent, Angew. Chem. Int. Ed., 2002, 41(18), 3479-3480

Jin-xian Wang, Ying Fu, Yulai Hu, A New method for Carbon-Carbon Double Bond Formation from Reaction of Organic Zinc Reagents with Aldehydes Catalyzed by Nickel(II) complex, Angew. Chem. Int. Ed., 2002, 41(15), 2757

Yulai Hu, Weiping Chen, Anna M. Banet Osuna, Jon A. Iggo and Jianliang Xiao, Fast and unprecedented chemoselective hydroformylation of acrylates with a fluoropolymer ligand in supercritical CO2, Chem. Commun., 2002, 788-789

Yulai Hu, Anna M. Banet, Weiping Chen, Jianliang, Xiao: Rapid Hydroformylation of Alkyl Acrylates in Supercritical Carbon Dioxide, Chem. Commun., 2001, 725-726