闫喜涛
副教授 硕导
个人简介
2015年6月‒至今:西北农林科技大学理学院/化学与药学院,陕西省天然产物化学生物学重点实验室,化学生物学系 2016年4月‒2022年3月:西北农林科技大学,生物学学科,博士后研究 2015年2月‒2015年8月:韩国高丽大学药学院,生药学学科,博士后研究 2010年9月‒2015年2月:韩国国立忠南大学药学院,药物化学专业,药学博士 2006年9月‒2010年7月:吉林农业大学中药材学院,中药学专业,理学学士
研究领域
1. 秦巴山区特色植物药及菌物药的化学和药理学研究 2. 中草药中活性成分的分析、分离、鉴定、生物活性评价及作用机制研究 3. 天然产物的结构修饰及构效关系研究
近期论文
Xie JY, Wang ZX, Liu WY, Liu HW, Li D, Sang YF, Yang Z, Gao JM*, Yan XT*. Hyperelatolides A-D, Antineuroinflammatory Constituents with Unusual Carbon Skeletons from Hypericum elatoides. J. Nat. Prod. 2023, 86(8): 1910-1918. doi: 10.1021/acs.jnatprod.3c00226. Yan XT*, Chen JX, Wang ZX, Zhang RQ, Xie JY, Kou RW, Zhou HF, Zhang AL, Wang MC, Ding YX, Gao JM*. Hyperhubeins A-I, Bioactive Sesquiterpenes with Diverse Skeletons from Hypericum hubeiense. J. Nat. Prod. 2023, 86(1): 119-130. doi: 10.1021/acs.jnatprod.2c00810. Xie JY, Li P, Yan XT*, Gao JM*. Discovery from Hypericum elatoides and synthesis of hyperelanitriles as α-aminopropionitrile-containing polycyclic polyprenylated acylphloroglucinols. Commun. Chem. 2024, 7(1): 1. doi: 10.1038/s42004-023-01091-1. Xie JY, Jin Q, Gao JM, Zong SC, Yan XT*. Two new benzophenone glycosides from the aerial parts of Hypericum przewalskii. Nat. Prod. Res. 2022, 36(14): 3520-3528. doi: 10.1080/14786419.2020.1865955. Yan XT, An Z, Huangfu Y, Zhang YT, Li CH, Chen X, Liu PL, Gao JM*. Polycyclic polyprenylated acylphloroglucinol and phenolic metabolites from the aerial parts of Hypericum elatoides and their neuroprotective and anti-neuroinflammatory activities. Phytochemistry 2019, 159: 65-74. doi: 10.1016/j.phytochem.2018.12.011. Yan XT, An Z, Tang D, Peng GR, Cao CY, Xu YZ, Li CH, Liu PL, Jiang ZM, Gao JM*. Hyperelatosides A-E, biphenyl ether glycosides from Hypericum elatoides, with neurotrophic activity. RSC Adv. 2018, 8(47): 26646-26655. doi: 10.1039/c8ra05322g. Yan XT, Lee SH, Li W, Jang HD*, Kim YH*. Terpenes and sterols from the fruits of Prunus mume and their inhibitory effects on osteoclast differentiation by suppressing tartrate-resistant acid phosphatase activity. Arch. Pharm. Res. 2015, 38(2): 186-192. doi: 10.1007/s12272-014-0389-2. Yan XT, Lee SH, Li W, Sun YN, Yang SY, Jang HD*, Kim YH*. Evaluation of the antioxidant and anti-osteoporosis activities of chemical constituents of the fruits of Prunus mume. Food Chem. 2014, 156: 408-415. doi: 10.1016/j.foodchem.2014.01.078. Yan XT, Li W, Sun YN, Yang SY, Lee SH, Chen JB, Jang HD*, Kim YH*. Identification and biological evaluation of flavonoids from the fruits of Prunus mume. Bioorg. Med. Chem. Lett. 2014, 24(5): 1397-1402. doi: 10.1016/j.bmcl.2014.01.028. Yan XT, Ding Y, Li W, Sun YN, Yang SY, Koh YS, Kim YH*. Two new phenolic compounds from Artemisia iwayomogi. Helv. Chim. Acta 2014, 97(2): 283-289. doi: 10.1002/hlca.201300170.