2002年本科毕业于兰州大学；2007年获兰州大学有机化学博士学位。2007-2009年任巴塞利亚药业（中国）研发组长；2009-2011年在新加坡国立大学从事博士后研究。2012年至今在西北大学任职教授/博导。已在国际著名化学期刊Nat. Commun., J. Am. Chem. Soc., Angew. Chem. Int. Ed., Chem. Sci., Org. Lett.等发表研究论文40多篇,已被引用2000余次。主持承担国家自然科学基金、陕西省杰出青年基金、教育部博士点基金、陕西省自然科学基金、留学回国择优支持计划（优秀类）、西北大学优秀青年学术骨干支持计划等项目。2014年获“Thieme Chemistry Journals Award”；2018年获陕西省杰出青年基金。

有机合成方法学，有机不对称催化，天然产物合成

Hu, Q.-Q.#; Geng, Z.-X.#; Bai, X.; Chen, J.*; Zhou, L.* Lewis Acid Catalyzed Divergent Reaction of Bicyclo[1.1.0]butanes with Quinones for the Synthesis of Diverse Polycyclic Molecules. Angew. Chem. Int. Ed. 2025, 64, e202506228. Hu, Q.-Q.#; Wang, L.-Y.#; Chen, X.-H.; Geng, Z.-X.; Chen, J.*; Zhou, L.* Lewis Acid Catalyzed Cycloaddition of Bicyclobutanes with Ynamides for the Synthesis of Polysubstituted 2-Amino-bicyclo[2.1.1]hexenes. Angew. Chem. Int. Ed. 2024, 63, e202405781. Xu, W.-L.#; Zhang, R.-X.#; Wang, H.; Chen, J. *; Zhou, L.* Helicoselective Synthesis of Indolohelicenoids through Organocatalytic Central-to-Helical Chirality Conversion. Angew. Chem. Int. Ed. 2024, 63, e202318021. Wang, C.-J.#; Meng, H.-J.#; Tang, Y.; Chen, J.*; Zhou, L.* Aromatic Amine and Chiral Phosphoric Acid Synergistic Catalyzed Cascade Reaction of Alkynylnaphthols with Aldehydes. Org. Lett. 2024, 26, 1489-1494. Sun, H.-R.#; Yang, L.#; Li, Y.; Yu, L.; Gou, B.-B.; Sharif, A.; Jian, Q.-S.; Chen, J.*; Zhou, L.* Organocatalytic Asymmetric [2+2] Cycloaddition of Alkynes with Quinones. Sci. China Chem. 2023, 66, 2292-2299. Sun, H.-R.#; Sharif, A.#; Chen, J.*; Zhou, L.*, Atroposelective Synthesis of Heterobiaryls through Ring Formation. Chem. Eur. J. 2023, 29, e202300183。 Gou, B.-B.#; Tang, Y.#; Lin, Y.-H.#; Yu, L.; Jian, Q.-S.; Sun, H.-R.; Chen, J.; Zhou, L.*, Modular Construction of Heterobiaryl Atropisomers and Axially Chiral Styrenes via All-Carbon Tetrasubstituted VQMs. Angew. Chem. Int. Ed. 2022, 61, e202208174. Yang, H.#; Sun, H.-R.#; He, R.-Q.; Yu, L.; Hu, W.; Chen, J.; Yang, S.; Zhang, G.-G.; Zhou, L.*, Organocatalytic cycloaddition of alkynylindoles with azonaphthalenes for atroposelective construction of indole-based biaryls. Nat. Commun. 2022, 13, 632. Sharif, A.#; Sun, H.-R.#; Xu, W.-L.; Gou, B.-B.; Yang, L.; Li, Y.; Chen, J.*; Zhou, L.*, A Dehydrogenative Inverse Electron Demand Diels–Alder Reaction for the Synthesis of Functionalized Pyranones. Org. Lett. 2022, 24, 4316-4321. Xu, W.-L.#; Zhao, W.-M.#; Zhang, R.-X.; Chen, J.; Zhou, L.*, Organocatalytic cycloaddition–elimination cascade for atroposelective construction of heterobiaryls. Chem. Sci. 2021, 12, 14920-14926. Yang, H.#; Xu, W.-L.#; Zeng, X.-Y.; Chen, J.; Yu, L.*; Zhou, L.*, Hydrogen Bond Assisted Central-to-Spiro Chirality Transfer and Central-to-Axial Chirality Conversion: Asymmetric Synthesis of Spirocycles. Org. Lett. 2021, 23, 9315-9320. Yang, H.; Chen, J.; Zhou, L.*, Construction of Axially Chiral Compounds via Central-to-Axial Chirality Conversion. Chemistry – An Asian Journal 2020, 15, 2939-2951. Xu, W.-L.#; Hu, W.#; Zhao, W.-M.; Wang, M.; Chen, J.*; Zhou, L.*, Copper(I)/DDQ-Mediated Double-Dehydrogenative Diels–Alder Reaction of Aryl Butenes with 1,4-Diketones and Indolones. Org. Lett. 2020, 22, 7169-7174. Wang, S.-J.#; Wang, Z.#; Tang, Y.; Chen, J.*; Zhou, L.*, Asymmetric Synthesis of Quinoline-Naphthalene Atropisomers by Central-to-Axial Chirality Conversion. Org. Lett. 2020, 22, 8894-8898. Sun, H.-R.#; Zhao, Q.#; Yang, H.; Yang, S.; Gou, B.-B.; Chen, J.; Zhou, L.*, Chiral Phosphoric-Acid-Catalyzed Cascade Prins Cyclization. Org. Lett. 2019, 21, 7143-7148. Gou, B.-B.; Liu, H.-F.; Chen, J.*; Zhou, L.*, Palladium-Catalyzed Site-Selective C(sp3)–H Arylation of Phenylacetaldehydes. Org. Lett. 2019, 21, 7084-7088. Hu, Y.-L.#; Wang, Z.#; Yang, H.#; Chen, J.; Wu, Z.-B.; Lei, Y.; Zhou, L.* Conversion of two stereocenters to one or two chiral axes: atroposelective synthesis of 2,3-diarylbenzoindoles. Chem. Sci. 2019, 10, 6777-6784. (Back cover) Xu, W.-L.; Tang, L.; Ge, C.-Y.; Chen, J.*; Zhou, L.* “Synthesis of Tetrahydroisoindolinones via a Metal-Free Dehydrogenative Diels-Alder Reaction” Adv. Synth. Catal. 2019, 361, 2268-2273. Gou, B.-B.; Yang, H.; Sun, H.-R.; Chen, J.*; Wu, J.*; Zhou, L.* “Phenanthrene Synthesis by Palladium(II)-Catalyzed γ-C(sp2)–H Arylation, Cyclization, and Migration Tandem Reaction” Org. Lett. 2019, 21, 80-84. Xu, W.-L.; Zhang, H.; Hu, Y.-L.; Yang, H.; Chen, J.*; Zhou, L.* “Metal-Free Dehydrogenative Diels–Alder Reactions of Prenyl Derivatives with Dienophiles via a Thermal Reversible Process”Org. Lett. 2018, 20, 5774-5778. Feng, W.#; Yang, H.#; Wang, Z.; Gou, B.-B.; Chen, J.*; Zhou, L.* “Enantioselective [3 + 2] Formal Cycloaddition of 1-Styrylnaphthols with Quinones Catalyzed by a Chiral Phosphoric Acid” Org. Lett. 2018, 20, 2929-2933. Zhao, M.#; Liu, J.-L.#; Liu, H.-F.; Chen, J.*; Zhou, L.* “Construction of Bisbenzopyrone via N-Heterocyclic Carbene Catalyzed Intramolecular Hydroacylation–Stetter Reaction Cascade” Org. Lett. 2018, 20, 2676-2679. Wang, J.-J.#; Yang, H.#; Gou, B.-B.; Zhou, L.*; Chen, J.* “Enantioselective Organocatalytic Sulfenylation of β-Naphthols” J. Org. Chem. 2018, 83, 4730-4738. Zhao, M.#; Zhang, Y.-T.#; Chen, J.*; Zhou, L.* “Enantioselective Reactions Catalyzed by N-Heterocyclic Carbenes” Asian J. Org. Chem. 2018, 7, 54-69.