陈洁 照片

陈洁

教授

所属大学: 西北大学

所属学院: 化学与材料科学学院

邮箱:
chmchenj@nwu.edu.cn

个人主页:
https://chem.nwu.edu.cn/cmsproduct/front/commonLeft?channelId=27#childChannelId=21

个人简介

2009年获兰州大学有机化学博士学位。2009.8-2010.7在南洋理工大学、2010.8-2011.12在新加坡国立大学从事博士后研究。2012年至今在西北大学任职。研究方向为有机合成方法学、有机催化,天然产物合成等。已在国际著名有机化学期刊Angew. Chem. Int. Ed., J. Am. Chem. Soc., Chem. Sci., Org. Lett., Chem. Commun., Adv. Synth. Catal., J. Org. Chem.等发表研究论文30多篇。先后主持承担国家自然科学基青年项目、教育部留学回国人员启动基金、陕西省自然科学基金、西北大学优秀青年学术骨干支持计划等项目。

研究领域

有机合成,不对称催化,手性功能分子合成

近期论文

Xu, W.-L.; Zhang, R.-X.; Wang, H.; Chen, J. *; Zhou, L.* Helicoselective Synthesis of Indolohelicenoids through Organocatalytic Central-to-Helical Chirality Conversion. Angew. Chem. Int. Ed. 2024, 63, e202318021. Wang, C.-J.; Meng, H.-J.; Tang, Y.; Chen, J.*; Zhou, L.* Aromatic Amine and Chiral Phosphoric Acid Synergistic Catalyzed Cascade Reaction of Alkynylnaphthols with Aldehydes. Org. Lett. 2024, 26, 1489-1494. Sun, H.-R.; Yang, L.; Li, Y.; Yu, L.; Gou, B.-B.; Sharif, A.; Jian, Q.-S.; Chen, J.*; Zhou, L.* Organocatalytic Asymmetric [2+2] Cycloaddition of Alkynes with Quinones. Sci. China Chem. 2023, 66, 2292-2299. Jian, Q.-S.; Gou, B.-B.; Wang, S.-J.; Sun, H.-R.; Sharif, A.; Wang, Y.-Q.; Zhou, L.*; Chen, J.*, Synthesis of quinol-type heterobiaryls via an acid-catalyzed heteroannulation of alkynes and o-aminobenzaldehydes. Org. Chem. Front. 2023, 10, 1936-1941. Sun, H.-R.#; Sharif, A.#; Chen, J.*; Zhou, L.*, Atroposelective Synthesis of Heterobiaryls through Ring Formation. Chem. Eur. J. 2023, 29, e202300183. Wang, L.-Y.; Yang, L.; Chen, J.*; Zhou, L., Chiral Phosphoric Acid Catalyzed Asymmetric Cycloadditions: from Alkenes to Alkynes. Synlett 2023, 34, 1200-1214. Cai, W.-Y.; Ding, Q.-N.; Zhou, L.*; Chen, J.*, Asymmetric Synthesis of Axially Chiral Molecules via Organocatalytic Cycloaddition and Cyclization Reactions. Molecules 2023, 28, 4306. Gou, B.-B.; Tang, Y.; Lin, Y.-H.; Yu, L.; Jian, Q.-S.; Sun, H.-R.; Chen, J.; Zhou, L., Modular Construction of Heterobiaryl Atropisomers and Axially Chiral Styrenes via All-Carbon Tetrasubstituted VQMs. Angew. Chem. Int. Ed. 2022, 61, e202208174. Yang, H.; Sun, H.-R.; He, R.-Q.; Yu, L.; Hu, W.; Chen, J.; Yang, S.; Zhang, G.-G.; Zhou, L., Organocatalytic cycloaddition of alkynylindoles with azonaphthalenes for atroposelective construction of indole-based biaryls. Nat. Commun. 2022, 13, 632. Sharif, A.; Sun, H.-R.; Xu, W.-L.; Gou, B.-B.; Yang, L.; Li, Y.; Chen, J.*; Zhou, L.*, A Dehydrogenative Inverse Electron Demand Diels–Alder Reaction for the Synthesis of Functionalized Pyranones. Org. Lett. 2022, 24, 4316-4321. Gou, B.-B.; Yang, S.; Sun, H.-R.; Jian, Q.-S.; Sharif, A.; Zhou, L.; Chen, J.*, Scandium Triflate Catalyzed Tandem Transfer Hydrogenation and Cyclization Reaction of o-Aminobenzaldehydes and o-Aminoacetophenone with Alcohols. J. Org. Chem. 2021, 86 (24), 17673-17683. Xu, W.-L.; Zhao, W.-M.; Zhang, R.-X.; Chen, J.; Zhou, L., Organocatalytic cycloaddition–elimination cascade for atroposelective construction of heterobiaryls. Chem. Sci. 2021, 12, 14920-14926. Yang, H.; Xu, W.-L.; Zeng, X.-Y.; Chen, J.; Yu, L.; Zhou, L., Hydrogen Bond Assisted Central-to-Spiro Chirality Transfer and Central-to-Axial Chirality Conversion: Asymmetric Synthesis of Spirocycles. Org. Lett. 2021, 23, 9315-9320. Xu, W.-L.; Hu, W.; Zhao, W.-M.; Wang, M.; Chen, J.*; Zhou, L.*, Copper(I)/DDQ-Mediated Double-Dehydrogenative Diels–Alder Reaction of Aryl Butenes with 1,4-Diketones and Indolones. Org. Lett. 2020, 22, 7169-7174. Wang, S.-J.; Wang, Z.; Tang, Y.; Chen, J.*; Zhou, L.*, Asymmetric Synthesis of Quinoline-Naphthalene Atropisomers by Central-to-Axial Chirality Conversion. Org. Lett. 2020, 22, 8894-8898. Yang, H.; Sun, H.-R.; Xue, R.-D.; Wu, Z.-B.; Gou, B.-B.; Lei, Y.; Chen, J.*; Zhou, L.*, Selectfluor-Mediated Stereoselective [1 + 1 + 4 + 4] Dimerization of Styrylnaphthols. Org. Lett. 2019, 21, 9829-9835. Gou, B.-B.; Liu, H.-F.; Chen, J.*; Zhou, L.*, Palladium-Catalyzed Site-Selective C(sp3)–H Arylation of Phenylacetaldehydes. Org. Lett. 2019, 21, 7084-7088. Hu, Y.-L.; Gou, B.-B.; Wang, J.; Zhao, M.; Liu, J.-L.; Chen, J.*; Zhou, L.*, N-Heterocyclic Carbene Catalyzed Stereoselective Synthesis of 2-Nitro-thiogalactosides. Synthesis 2019, 51, 3451-3461. Hu, Y.-L.; Wang, Z.; Yang, H.; Chen, J.; Wu, Z.-B.; Lei, Y.; Zhou, L.* Conversion of two stereocenters to one or two chiral axes: atroposelective synthesis of 2,3-diarylbenzoindoles. Chem. Sci. 2019, 10, 6777-6784. Xu, W.-L.; Tang, L.; Ge, C.-Y.; Chen, J.*; Zhou, L.* “Synthesis of Tetrahydroisoindolinones via a Metal-Free Dehydrogenative Diels-Alder Reaction” Adv. Synth. Catal. 2019, 361, 2268-2273. Gou, B.-B.; Yang, H.; Sun, H.-R.; Chen, J.*; Wu, J.*; Zhou, L.* “Phenanthrene Synthesis by Palladium(II)-Catalyzed γ-C(sp2)–H Arylation, Cyclization, and Migration Tandem Reaction” Org. Lett. 2019, 21, 80-84.