学习经历 2005.9 – 2009.7 厦门大学机电工程系，机械设计制造及其自动化，工学学士； 2009.8 – 2010.7 宁夏海原县职业中学，数学教师（支教）； 2010.9 – 2015.6 厦门大学仪器与电气工程系，精密仪器及机械，工学博士； 2015.7 – 2018.3 中国科学院自动化研究所，控制科学与工程，博士后。 研究方向 医疗检测仪器及其配套微流控芯片的研发及其产业化。 儿童骨龄智能判读算法开发。 疫苗免疫原的人工智能设计。

医疗机器人 医疗大数据分析

[1] Dongxu Zhang, Yang Yan, Yulin Huang, Bowen Liu, Qingbing Zheng, Jun Zhang Ningshao Xia*. Unsupervised Cryo-EM Images Denoising and Clustering based on Deep Convolutional Autoencoder and K-Means++. IEEE Transactions on Medical Imaging. 2023, 42(5): 1509-1521. [2] Dongxu Zhang, Runxin Gao, Shaolei Huang, Yulin Huang, Jianbin Zhang, Xiaosong Su, Shiyin Zhang, Shengxiang Ge*, Jun Zhang*, Ningshao Xia*. All-in-one microfluidic chip for 30-min quantitative point-of-care-testing of nucleic acids. Sensors and Actuators B: Chemical. 2023, 390: 133939. [3] Dongxu Zhang, Bowen Liu, Yulin Huang, Yang Yan, Shaowei Li, Jinshui He, Shuyun Zhang, Jun Zhang, Ningshao Xia*. An Automated TW3-RUS Bone Age Assessment Method with Ordinal Regression-Based Determination of Skeletal Maturity. Journal of Digital Imaging. 2023: 1-15. [4] Dongxu Zhang, Yang Hu, Runxin Gao, Shengxiang Ge, Jun Zhang, Xianglei Zhang*, Ningshao Xia*. Numerical and experimental investigation on the performance of rapid ultrasonic-assisted nucleic acid extraction based on dispersive two-phase flow. Analytica Chimica Acta, 2023: 342176. [5] Dongxu Zhang, Zengguang Hou, Yinbiao Guo, Yongqiang Hong, Ri Pan. Research on data fusion technology of the online monitoring system for bonnet polishing. Proceedings of the Institution of Mechanical Engineers, Part B: Journal of Engineering Manufacture. 2018, 232(8):1436-1443. [6] Dongxu Zhang, Guoqiang Liu, Yongkang Lai, Xiaohui Lin, and Weihuang Cai. Numerical Simulation and Application of a Channel Heat Sink with Diamond Ribs. Water 2023, 15, 3677. [7] Dongxu Zhang, Guo Bi, Zhiji Sun, Yinbiao Guo. Online monitoring of precision optics grinding using acoustic emission based on support vector machine. International Journal of Advanced Manufacturing Technology. 2015, 80(5): 761-774. [8] Dongxu Zhang, Ping Yang, Yanting Zhang, Guo Bi, Yinbiao Guo. Effects analysis of processing factors on surface quality in optical grinding using ε–support vector regression. Proceedings of the Institution of Mechanical Engineers, Part C: Journal of Mechanical Engineering Science. 2015, 229(18): 3449-3458. [9] JiaGeng Wu, Yang Yan, DongXu Zhang*, BoWen Liu, QingBing Zheng, XiaoLiang Xie, ShiQi Liu, ShengXiang Ge, ZengGuang Hou, NingShao Xia. Machine Learning for Structure Determination in Single-Particle Cryo-Electron Microscopy: A Systematic Review. IEEE Transactions on Neural Networks and Learning Systems. 2022, 33(2): 452-472. [10] Shaolei Huang, Yiquan An, Bangchao Xi, Xianglian Gong, Zhongfu Chen, Shan Shao, Shengxiang Ge, Jun Zhang, Dongxu Zhang*, Ningshao Xia*. Ultra-fast, sensitive and low-cost real-time PCR system for nucleic acid detection. Lab on a Chip 2023, 23(11): 2611-2622. [11] An, YiQuan, ShaoLei Huang, BangChao Xi, XiangLian Gong, JunHao Ji, You Hu, YiJie Ding, DongXu Zhang*, ShengXiang Ge, Jun Zhang, NingShao Xia. Ultrafast Microfluidic PCR Thermocycler for Nucleic Acid Amplification. Micromachines. 2023, 14(3): 658. [12] Bangchao Xi, Shaolei Huang, Yiquan An, Xianglian Gong, Jiayu Yang, Juntian Zeng, Shengxiang Ge, Dongxu Zhang*. Sophisticated and precise: design and implementation of a real-time optical detection system for ultra-fast PCR. RSC advances. 2023, 13(29): 19770-19781. [13] Xiaohui Lin, Weihuang Cai, Shaolei Huang, Sijie Zhu, Dongxu Zhang*. Conjugate Heat Transfer Analysis and Heat Dissipation Design of Nucleic Acid Detector Instrument. Applied Sciences. 2022, 12(23): 11966. [14] Shaolei Huang, Jiageng Wu, Haozheng Dai, Runxin Gao, Hongyu Lin, Dongxu Zhang*, Shengxiang Ge. Development of amplification system for point-of-care test of nucleic acid. Computer Methods in Biomechanics and Biomedical Engineering. 2022, 25(9): 961-970. [15] Shaowei Li, Bowen Liu, Shulian Li, Xinyu Zhu, Yang Yan, Dongxu Zhang*. A deep learning-based computer-aided diagnosis method of X-ray images for bone age assessment. Complex & Intelligent Systems. 2021: 1-11. [16] Xianglei Zhang, Yang Hu, Runxin Gao, Shengxiang Ge, Dongxu Zhang*. Numerical and Experimental Investigation of Liquid Residue in 90° Bend Microchannel Based on Gas–Liquid Two-Phase Flow. Fluid Dynamics. 2021, 56(Suppl 1): S34-S52. [17] Xiaoping Min, Da Fu, Jianzhong Zhang, Juntian Zeng, Zhenyu Weng, Wendi Chen, Shiyin Zhang, Dongxu Zhang*, Shengxiang Ge, Jun Zhang and Ningshao Xia. An automated microfluidic chemiluminescence immunoassay platform for quantitative detection of biomarkers. Biomedical Microdevices. 2018, 20: 91. [18] Jiasu Xu, Jin Wang, Shuizhen He, Xiaosong Su, Zecheng Zhong, Weibo Zhong, Lizhen Yan, Shaolei Huang, Jiayu Yang, Runxin Gao, Jianbin Zhang, Juntian Zeng, Dongxu Zhang, Tingdong Li, Shiyin Zhang*, Shengxiang Ge*, Jun Zhang, Ningshao Xia. Accurate nucleic acid quantification in a single sample tube without the need for calibration. Analytica Chimica Acta. 2021, 1167: 338599. [19] Jiasu Xu, Jin Wang, Zecheng Zhong, Xiaosong Su, Kunyu Yang, Zhongfu Chen, Dongxu Zhang, Tingdong Li, Yingbin Wang, Shiyin Zhang*, Shengxiang Ge*, Jun Zhang, Ningshao Xia. Room-temperature-storable PCR mixes for SARS-CoV-2 detection. Clinical biochemistry. 2020, 84: 73-78. [20] 张东旭，杨平，毕果，杨旭，叶世蔚，郭隐彪. 磨削阶段大口径非球面拼接测量技术. 机械工程学报，2015, 51(04): 22-29. [21] 张东旭，杨平，杨峰，王詹帅，谢银辉，郭隐彪. 基于多体系统理论的精密检测平台空间误差建模与补偿. 兵工学报，2014, 35(04): 501-508. [22] 张东旭，毕果，郭隐彪，王健，王詹帅，潘日. 精密检测平台定位误差自适应补偿技术. 强激光与粒子束，2014, 26(02): 121-126. [23] 赵巍，张东旭*，王琦琛，陈杨辉，曾俊添，苏晓菘，张师音，葛胜祥. 微流控芯片通用性微阀的设计实现与性能. 科学技术与工程，2020，20(33): 13667-13672. [24] 王琦琛，高润鑫，曾俊添，张东旭*，葛胜祥，夏宁邵. 基于实效边界模型的微阀关键特征公差设计. 组合机床与自动化加工技术，2022(03): 1-5. [25] 杨佳羽，曾俊添，奚邦朝，刘国镪，黄绍磊，张东旭*. 面向核酸现场快速检测的多重实时荧光检测系统. 应用光学，2023, 44(04): 859-867. [26] 颜阳，郑清炳，张东旭*，李少伟，葛胜祥，张军，夏宁邵. 基于对比学习的冷冻电镜单颗粒图像聚类算法. 厦门大学学报(自然科学版)，2022, 61(06): 1053-1061. [27] 奚邦朝，杨佳羽，黄绍磊，戴皓正，曾俊添，张东旭*. 用于核酸现场检测的直轴型多通道光学检测系统. 激光与光电子学进展，2023,60(17): 335-343. [28] Yang Yan, Jiageng Wu, Bowen Liu, Qingbing Zheng, Dongxu Zhang*, Shengxiang Ge, Jun Zhang, Ningshao Xia. A Novel Clustering Method Using Variational Autoencoder with Reliable Sample Decision and Balanced K-Means++ for Single-particle Cryo-EM Images. 2021 IEEE Data Driven Control and Learning Systems Conference (DDCLS), Suzhou, P.R. China, 2021.05.14-05.16. [29] Dongxu Zhang*, Zhenyu Weng, Ya Zhang, Haozheng Dai, Jiageng Wu, Xiaoping Min and Shengxiang Ge. A hot embossing robot for bonding microfluidic chips: design, control and test. IEEE International Conference on Real-time Computing and Robotics (RCAR). Irkutsk, Russia, 2019.08.04-08.09. [30] Dongxu Zhang, Zengguang Hou*, Long Cheng, Guibin Bian, Xiaoliang Xie and Liang Peng. ε-SVR-based estimation for the motion trajectory of human lower limb using acceleration signals. IEEE International Conference on Information and Automation (ICIA). Ningbo, P.R. China, 2016.08.01-08.03. [31] Dongxu Zhang*, Zhenzhong Wang, Zhaishuai Wang, Yanting Zhang, Xin Li, Ri Pan and Yinbiao Guo. Research for rejecting the redundant data during section splicing large-aperture aspheric optical elements. 2nd International Conference on Manufacturing Engineering and Process, Vancouver, Canada, 2013.04.13-04.14.