研究员（美国Los Alamos国家实验室） 博士后（美国University of Florida） 博士 (厦门大学) 硕士 (厦门大学) 学士 (浙江大学）

质谱分析与应用,质谱及其他分析仪器新方法、新技术的研发

Research and development of analytical instrument 1. Development of mass spectrometor and new technique of signal detection 2. Study of ion source and interfacing technology 3. Other analytical instruments combined with MS methods Applications of analytical instruments: Research of analytical chemistry focusing on MS in various fields including biology, medicine, environment, metallurgy, mineral and security inspection.

Wang Y, Xu Z, Hang L, Xing T, et al. Lycoptera Fossil Elemental Imaging and Paleo-Environment Research via Laser Ionization Time-of-Flight Mass Spectrometry[J]. Atomic Spectroscopy, 2023, 44(2): 55-64. Ma S, Zhang Z, Xu Z, et al. Quantitative imaging of fluorine in human teeth by cryogenic laser ionization time-of-flight mass spectrometry[J]. Journal of Analytical Atomic Spectrometry, 2023, 38(3): 595-602. Ma S, Leng Y, Li X, et al. High spatial resolution mass spectrometry imaging for spatial metabolomics: Advances, challenges, and future perspectives[J]. TrAC Trends in Analytical Chemistry, 2022: 116902. Zhang Z, Ma S, Hang L, et al. Direct Quantitative Analysis of Fluorine in Solid Samples by Cryogenic Laser Ablation and Ionization Time-of-Flight Mass Spectrometry[J]. Analytical Chemistry, 2022. Li, X., L. Hang, T. Wang, Y. Leng, H. Zhang, Y. Meng, Z. Yin and W. Hang (2021). "Nanoscale Three-Dimensional Imaging of Drug Distributions in Single Cells via Laser Desorption Post-Ionization Mass Spectrometry." Journal of the American Chemical Society 143(51): 21648-21656. Meng, Y., L. Hang and W. Hang (2021). "Direct determination of nutrient and toxic elements in original kelp by high irradiance laser ionization time-of-flight mass spectrometry." Spectrochimica Acta Part B: Atomic Spectroscopy 176: 106041. Meng, Y., C. Gao, Q. Lu, S. Ma and W. Hang (2021). "Single-Cell Mass Spectrometry Imaging of Multiple Drugs and Nanomaterials at Organelle Level." ACS Nano 15(8): 13220-13229. Zhang, S.-P., J.-S. Lin, R.-K. Lin, P. M. Radjenovic, W.-M. Yang, J. Xu, J.-C. Dong, Z.-L. Yang, W. Hang, Z.-Q. Tian and J.-F. Li (2020). "In situ Raman study of the photoinduced behavior of dye molecules on TiO2(hkl) single crystal surfaces." Chemical Science 11(25): 6431-6435. Xu, Z., L. Hang, Q. Lu, N. Guo and W. Hang (2020). "A preliminary comparison of time-of-flight laser ionization and secondary ion mass spectrometry in solids analysis." Spectrochimica Acta Part B: Atomic Spectroscopy 167: 105824. Wang, T., X. Cheng, H. Xu, Y. Meng, Z. Yin, X. Li and W. Hang (2020). "Perspective on Advances in Laser-Based High-Resolution Mass Spectrometry Imaging." Analytical Chemistry 92(1): 543-553. Meng, Y., S. Ma, Z. Zhang and W. Hang (2020). "3D Nanoscale Chemical Imaging of Core–Shell Microspheres via Microlensed Fiber Laser Desorption Postionization Mass Spectrometry." Analytical Chemistry 92(14): 9916-9921. Meng, Y., C. Gao, Z. Lin, W. Hang and B. Huang (2020). "Nanoscale laser-induced breakdown spectroscopy imaging reveals chemical distribution with subcellular resolution." Nanoscale Advances 2(9): 3983-3990. Meng, Y., X. Cheng, T. Wang, W. Hang, X. Li, W. Nie, R. Liu, Z. Lin, L. Hang, Z. Yin, B. Zhang and X. Yan (2020). "Micro-Lensed Fiber Laser Desorption Mass Spectrometry Imaging Reveals Subcellular Distribution of Drugs within Single Cells." Angewandte Chemie International Edition 59(41): 17864-17871. Lu, Q., R. Lin, C. Du, Y. Meng, M. Yang, R. Zenobi and W. Hang (2020). "Metal Probe Microextraction Coupled to Dielectric Barrier Discharge Ionization–Mass Spectrometry for Detecting Drug Residues in Organisms." Analytical Chemistry 92(8): 5921-5928. Lin, R., Q. Lu, Z. Lin, W. Hang and B. Huang (2020). "Laser-induced acoustic desorption coupled with electrospray ionization mass spectrometry for rapid qualitative and quantitative analysis of glucocorticoids illegally added in creams." Analyst 145(20): 6625-6631. Cheng, X., Z. Yin, L. Rong and W. Hang (2020). "Subcellular chemical imaging of structurally similar acridine drugs by near-field laser desorption/laser postionization mass spectrometry." Nano Research 13(3): 745-751. Cheng, X., T. Wang, Z. Yin and W. Hang (2020). "Single-cell imaging of AuNPs and AgNPs by near-field desorption ionization mass spectrometry." Journal of Analytical Atomic Spectrometry 35(5): 927-932. 林铮, 孟一凡, 王彤彤 and 杭纬 (2020). "激光后电离技术对高电离能元素的信号增强." 质谱学报 41(2): 175-180. Xie, B., J. Lin, K. Sui, Z. Huang, Z. Chen and W. Hang (2019). "Differential diagnosis of multielements in cancerous and non-cancerous esophageal tissues." Talanta 196: 585-591. HANG Le, XU Zhou-yi, HANG Wei, HUANG Ben-li. Recent Technical and Application Development of Atomic Spectrometry in China[J]. Spectroscopy and Spectral Analysis, 2019,39(5): 1329-1339 LI Xiao-ping, YIN Zhi-bin, CHENG Xiao-ling, LIU Rong, HANG Wei. Laser Desorption Time-of-Flight Mass Spectrometer for Sub-Micrometer-Scale Mass Spectrometry Imaging Using Near-Field Optics Technique[J]. Spectroscopy and Spectral Analysis, 2019,39(5): 1354-1358. Zhibin Yin, Xiaoling Cheng, Rong Liu, Xiaoping Li, Le Hang, Wei Hang*, Jingyi Xu, Xiaomei Yan*, Jianfeng Li*, Zhongqun Tian. Chemical and Topographical Single‐Cell Imaging by Near‐Field Desorption Mass Spectrometry[J]. Angewandte Chemie International Edition, 2019. Lin Zhi-Yi, Jian Jun-Tao, Wang Xiao-Hua, Hang Wei. Expansion characteristics of atom and ion component in laser-induced aluminum plasma. Acta Phys. Sin., 2018, 67(18): 185201. doi: 10.7498/aps.67.20180595. Yin, Z., L. Hang, R. Liu, W. Hang and B. Huang (2018). "Improved detection sensitivity of elements in solids via laser postionization in laser desorption time-of-flight mass spectrometry." Journal of Mass Spectrometry 53(5): 435-443. Wang, X., Z. Liang, Y. Meng, T. Wang, W. Hang and B. Huang (2018). "Sub-microanalysis of solid samples with near-field enhanced atomic emission spectroscopy." Spectrochimica Acta Part B: Atomic Spectroscopy 141: 1-6. Lin, R., B. Xie, C. Du, W. Hang and B. Huang (2018). "Pulsed micro-discharge ambient ionization mass spectrometry." International Journal of Mass Spectrometry 434: 123-129. Li, X., Z. Liang, S. Zhang, T. Wang and W. Hang (2018). "Sub-micrometer-scale chemical analysis by nanosecond-laser-induced tip-enhanced ablation and ionization time-of-flight mass spectrometry." Nano Research 11(11): 5989-5996. Hang, L., Z. Xu, Z. Yin and W. Hang (2018). "Approaching Standardless Quantitative Elemental Analysis of Solids: Microsecond Pulsed Glow Discharge and Buffer-Gas-Assisted Laser Ionization Time-of-Flight Mass Spectrometry." Analytical Chemistry 90(22): 13222-13228.