以骨代谢相关疾病（骨质疏松、骨关节炎、骨瘤等）的新药研究为目的，设计新型有机小分子化合物，发展高效合成它们的方法，运用新发展的合成方法合成化合物，并开展药理药效研究，最终发现新型候选药物。已在Journal of Medicinal Chemistry、European Journal of Medicinal Chemistry、Organic Letters等杂志发表 SCI论文20余篇，主持多项国家级，省市级项目，获得多项国家发明专利。指导的研究生被评为浙江省优秀毕业生，多次获得国家奖学金，学校一等奖学金。

骨细胞相关疾病（骨质疏松、骨关节炎、骨瘤等）的新药研究，包括药物化学和药理学

Synthesis and Antiosteoporotic Characterization of Diselenyl Maleimides: Discovery of a Potent Agent for the Treatment of Osteoporosis by Targeting RANKL. Journal of Medicinal Chemistry, 2024, 67: 17226−17242. (最终通讯作者，Top一区) Design, Synthesis, and Biological Evaluation of βTrifluoroethoxydimethyl Selenides as Potent Antiosteoporosis Agents. Journal of Medicinal Chemistry, 2024, 67: 7585−7602. (最终通讯作者，Top一区) Metal-Free Radical [3 + 2] Annulation of Tetraalkylthiuram Disulfide with Alkynes/Alkenes: An Approach of Synthesizing 1,3-Dithiole and 1,3-Ditholane Derivatives, Organic Letters, 2024, 26, 3230−3234. (最终通讯作者，Top一区) Metal-Free Oxidative Dearomatization−Alkoxylation/Acyloxylation of Indoles: Synthesis of 2Monosubstituted Indolin-3-ones, Organic Letters, 2023, 25: 7678−7682. (最终通讯作者，Top一区) Design, Synthesis and Biological Evaluation of Novel Chromone-Maleimide Hybrids as Potent Anti-Inflammatory Agents against LPS-Induced Acute Lung Injury. Bioorganic Chemistry, 2022, 128:106049. (最终通讯作者，Top一区)