研究领域
天然产物的衍生化合成与药效学评价
近期论文
1. Liu ZW, Liu ZM, Zhang XL, Xue PP, Zhang H. RY10-4 suppressed metastasis of MDA-MB-231 by stabilizing ECM and E-cadherin. Biomedicine & Pharmacotherapy, 2014, 68, 439-445
2. Liu ZW, Yuan QY, Zhang XN, Xiong CM, Xue PP, Ruan JL. RY10-4, a novel anti-tumor compound, exhibited its anti-angiogenesis activity by down-regulation the HIF-1α and inhibition phosphorylation of AKT and mTOR. Cancer Chemotherapy and Pharmacology 2012, 69(6), 1633-1640
3. Yuan QY, Liu ZW, Xiong CM, Wu LQ, Wang JP, Ruan JL. A novel, broad-spectrum antitumor compound containing the 1-hydroxycyclohexa-2,5-dien-4-one group: the disclosure of a new antitumor pharmacophore in protoapigenone 1. Bioorganic & Medicinal Chemistry Letters 2011, 21(11), 3427-3430. (SCI, IF: 2.661)
4. 刘子维，薛聘聘，石犊，赵洋，阮金兰。普通针毛蕨的化学成分和药理学活性研究进展[OL]。科技论文在线. 2013