学习经历 1992.09 - 1997.07，湖北医科大学，攻读学士学位 1997.09 - 2002.06，武汉大学，攻读博士学位 2003.09 - 2003.12，日本福岛医科大学，访问学者 2005.09 - 2007.09，加拿大 McMaster University，博士后 主要工作经历与任职 1997.07 - 2002.10，武汉大学生物化学与分子生物学系，助教 2002.10 - 2007.10，武汉大学生物化学与分子生物学系，讲师 2007.10 - 至今，武汉大学生物化学与分子生物学系，副教授 2008.10 - 至今，武汉大学生物化学与分子生物学系，博导

（1）糖尿病肾病的分子机制：主要关注肾小球硬化和肾小管间质纤维化的分子机制, 寻找防治糖尿病肾病的新策略。 （2）细胞信号传导：主要关注参与细胞外基质蛋白过度表达的信号通路。

1. Xue-Yu Sang, Jing-Jie Xiao, Qing Liu, Rui Zhu, Jia-Jia Dai, Cheng Zhang, Hong Yu, Si-Jun Yang, Bai-fang Zhang*. Regulators of calcineurin 1 deficiency attenuates tubulointerstitial fibrosis through improving mitochondrial fitness. The FASEB Journal. 2020, 34: 14539–14557. 通讯作者 2. Hong-Min Chen, Jia-Jia Dai, Rui Zhu, Xue-Yu Sang, Fang-Fang Peng, Hong Yu, Bai-fang Zhang*. RCAN1.4 mediates high glucose-induced matrix production by stimulating mitochondrial fission in mesangial cells. Biosci Rep. 2020, 40: BSR20192759. 通讯作者 3. Hong-Min Chen, Jia-Jia Dai, Rui Zhu, Fang-Fang Peng, Su-Zhen Wu, Hong Yu, Joan C. Krepinsky, Bai-fang Zhang*. Parathyroid hormone-related protein induces fibronectin up-regulation in rat mesangial cells through reactive oxygen species/Src/EGFR signaling. Biosci Rep. 2019, 39(4): BSR20182293. 通讯作者 4. Su-zhen Wu, SijunYang, Hong-min Chen, Fang-fang Peng, Hong Yu, Joan C. Krepinsky, Bai-fang Zhang*. Dual roles of parathyroid hormone related protein in TGF-β1 signaling and fibronectin up-regulation in mesangial cells. Biosci Rep. 2017, 37(5): BSR20171061. 通讯作者 5. Yan Chen, Fang-fang Peng, Jing Jin, Hong-min Chen, Hong Yu, Bai-fang Zhang*. Src-mediated ligand release-independent EGFR transactivation involves TGF-β-induced Smad3 activation in mesangial cells. Biochem Biophys Res Commun. 2017, 493(2): 914-920. 通讯作者 6. Wen Zhang, Su-zhen Wu, Jian Zhou, Hong-min Chen, Ye-lin Gong, Fang-fang Peng, Bai-fang Zhang*. Parathyroid hormone-related peptide (1-34) reduces alveolar bone loss in type 1 diabetic rats. Arch Oral Biol. 2017, 83: 13-19. 通讯作者 7. Fang-fang Peng, Ze-ling Xiao, Hong-min Chen, Yan Chen, Jian Zhou, Hong Yu, Bai-fang Zhang*. Parathyroid hormone inhibits TGF-β/Smad signaling and extracellular matrix proteins upregulation in rat mesangial cells. Biochem Biophys Res Commun. 2016, 478(3): 1093-8. 通讯作者 8. Jing Jin, Chao Peng, Su-zhen Wu, Hong-min Chen, Bai-fang Zhang*. Blocking VEGFR2/Caveolin-1 signaling contributes to renal protection of fasudil in streptozotocin-induced diabetic rats. Acta Pharmacol Sin. 2015, 36(7): 831-40. 通讯作者