教育背景： 1983.09 - 1988.07，湖北医学院，学士学位 1994.09 - 1997.07，湖北医科大学，硕士学位 工作经历： 1988.07 - 1994.09，湖北医学院，助教 1997.07 - 2000.11，湖北医科大学，讲师 2000.11 - 至今，武汉大学基础医学院免疫系，副教授 获奖荣誉： 2005 年获武汉大学 “本科教学质量” 优秀奖 2007 年获基础医学院 “创优迎评” 工作先进个人 2008 年获基础医学院 “本科教学状态评估” 工作先进个人 2010 年获武汉大学 “优秀本科教学管理工作者”

肿瘤分子病理与病理生理

1. Xu Xiaolong#, Zhang Jingwei#, Tian Yihao#, Gao Yang#, Dong Xin, Chen Wenbo, Yuan Xiaoning, Yin Weinan, Xu Jinjing, Chen Ke*, He Chunjiang*, Wei Lei*. CircRNA inhibits DNA damage repair by interacting with host gene, Molecular Cancer, 2020, 19(1):128. (SCI, IF= 15.302) 一区Top 2. Li Kai#, Zhang Jingwei#, Tian Yihao#, He Yanqi, Xu Xiaolong, Pan Wenting, Gao Yang, Chen Fangfang, Wei Lei*. The Wnt/beta-catenin/VASP positive feedback loop drives cell proliferation and migration in breast cancer, Oncogene, 2020, 39(11): 2258-2274. (SCI, IF= 7.971) 一区 3. Xu Xiaolong#, Yuan Xiaoning#, Ni Jiali, Guo Jing, Gao Yang, Yin Weinan, Li Feng, Wei Lei*, Zhang Jingwei*. MAGI2‐AS3 inhibits breast cancer by downregulating DNA methylation of MAGI2, J Cell Physiol, 2021, 236(2):1116-1130. (SCI, IF= 5.546) 二区 4. Xiang Ying, Yan Kai, Zheng Qian, Ke Haiqiang, Cheng Jie, Xiong Wenjun, Shi Xin, Wei Lei, Zhao Min, Yang Fei, Wang Ping, Lu Xing, Fu Li, Lu Xuemei* and Li Feng*. Histone demethylase KDM4B promotes DNA damage by activating longinterspersed nuclear element-1 (LINE-1). Cancer Reseach. 2019-01-01, (SCI, IF=9.13) 一区 5. Hu Pengchao #, Li Kai #, Tian Yihao, Pan Wenting, Wang Ying, Xu Xiaolong; He Yanqi, Gao yang, Wei Lei, Zhang Jingwei*. CREB1/Lin28/miR-638/VASP interactive network drives the development of breast cancer, International Journal of Biological Sciences, 2019, 15(12)：2733~2749. (SCI, IF= 4.858) 二区 6. Wang Ying#, Li Kai#, Han Song#, Tian Yihao, Hu Pengchao, Xu Xiaolong, He Yanqi, Pan Wenting, Gao Yang, Zhang Zun, Zhang Jingwei, Wei Lei*. Chlorotoxin targets ERalpha/VASP signaling pathway to combat breast cancer. 2019,Cancer Med 8(4): 1679-1693.(SCI, IF=3.357) 三区 7. Su Zijie #, Song Jiaxing #, Wang Zhongyuan #, Zhou Liang, Xia Yuqing, Yu Shubin, Qi Sun, Liu Shanshan, Zhao Liang, Li Shiyue, Wei Lei, Dennis A. Carson*, and Lu Desheng*. Tumor promoter TPA activates Wnt/β-catenin signaling in a casein kinase 1-dependent manner. Proc Natl Acad Sci USA. 2018 Aug 7; 115(32): E7522–E7531. (SCI, IF=9.504) 一区top 8. Siyu Xia, Jing Feng, Ke Chen, Yanbing Ma, Jing Gong, Fangfang Cai, Yuxuan Jin, Yang Gao, Linjian Xia, Hong Chang, Lei Wei, Leng Han and Chunjiang He. CSCD: a database for cancer-specific circular RNAs. Nucleic Acids Research, 2017. (SCI, IF= 10.161) 一区 9. Zhongyuan Wang, Bo Li, Liang Zhou, Shubin Yu, Zijie Su, Jiaxing Song, Qi Sun, Ou Sha,Xiaomei Wang, Wenqi Jiang, Karl Willert, Lei Wei, Dennis A. Carson, and Desheng Lu*. Prodigiosin inhibits Wnt/β-catenin signaling and exerts anticancer activity in breast cancer cells. (SCI, IF=9.423) 一区top 10. Wang Jing, Zhang Jingwei #, Wu Junzhu, Daji Luo, Su Ke, Shi Wentao, Liu Jian, Tian Yihao, Wei Lei*. MicroRNA-610 inhibits the migration and invasion of gastric cancer cells by suppressing the expression of vasodilator-stimulated phosphoprotein. European Journal of Cancer. 2012, 48(12):1904-1913. (△并列第一作者，SCI, IF= 7.191) 二区