1996年获武汉大学理学学士，2001年获武汉大学博士学位，博士学位论文获全国优秀博士论文提名奖和湖北省优秀博士论文。2001年破格晋升为副教授，后公派赴美国密苏里大学合作研究。2008年6月回到武汉大学，晋升为教授，并被遴选为博士生导师。2008年入选教育部新世纪人才计划，2010年获国家自然科学二等奖（第三完成人），2011年获湖北省青年科技奖。担任中国物理学会软物质与生物物理专业委员会委员、中国生物信息学会（筹）生物分子结构预测与模拟专业委员会常务委员、全国统计物理与复杂系统会议学术委员会委员等。主讲弘毅学堂物理班《热力学与统计物理》和研究生《高等固体物理》。

1，基于物理原理与人工智能，预测核酸分子结构、热力学及其与蛋白质作用； 2，基于物理原理与人工智能，预测核酸-药物小分子复合体结构及其热力学； 3，基于计算机模拟与人工智能，预测和理解核酸动态结构与其功能间的关系。

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