学习经历 1999 年 - 2003 年，就读于南开大学，专业为生物科学，获学士学位。 2003 年 - 2009 年，于中科院上海生命科学研究院生物化学与细胞生物学研究所攻读，获博士学位。 工作经历与任职 2010 年 - 2015 年，在加州大学欧文分校医学院担任博士后。 2015 年 - 2016 年，任加州大学欧文分校医学院研究助理。 2016 年 - 至今，担任武汉大学生命科学学院副研究员。

病原微生物

1. Mao Zhang, Cheng Zhu, Yuanyuan Duan, Tongbao Liu, Haoping Liu, Chang Su* and Yang Lu*. (2022) The intrinsically disordered region from PP2C phosphatases functions as a conserved CO2 sensor. Nature Cell Biology 24(7): 1029-1037. Highlighted at Nature Reviews Molecular Cell Biology, CO2 sensing through PP2C condensates. 23(4): 519; Highlighted at Nature Cell Biology, Intrinsically disordered CO2 sensors. 24(7): 1013-1014; Highlighted at Nature Chemical Biology, Sensing the air. 18(8): 793; Recommended by Faculty Option. 2. Kang Xiong#, Chang Su#, Qiangqiang Sun and Yang Lu*. (2021) Efg1 and Cas5 orchestrate cell wall damage response to Caspofungin in Candida albicans. Antimicrobial Agents and Chemotherapy 65(2): e01584-20. 3. Qiangqiang Sun, Kang Xiong, Yuncong Yuan, Jing Yu, Lianjuan Yang, Chao Shen, Chang Su* and Yang Lu*. (2020) Inhibiting fungal Echinocandin resistance by small-molecule disruption of Geranylgeranyltransferase type I activity. Antimicrobial Agents and Chemotherapy 64(2): e02046-19. 4. Yang Lu*#, Chang Su#, Shatarupa Ray, Yuncong Yuan, and Haoping Liu*. (2019) CO2 signaling through the Ptc2-Ssn3 axis governs sustained hyphal development of Candida albicans by reducing Ume6 phosphorylation and degradation. mBio 10(1): e02320-18. 5. Chang Su#, Jing Yu#, Qiangqiang Sun, Qian Liu, and Yang Lu*. (2018) Hyphal induction under the condition without inoculation in Candida albicans is triggered by Brg1-mediated removal of NRG1 inhibition. Molecular Microbiology108(4): 410-423. 6. Chang Su, Jing Yu, Yang Lu*. (2018) Hyphal development in Candida albicans from different cell states. Current Genetics 64(6):1239-1243. 7. Chang Su#, Yang Lu#, and Haoping Liu. (2016) N-acetylglucosamine sensing by a GCN5-related N-acetyltransferase induces transcription via chromatin histone acetylation in fungi. Nature Communications 7:12916. 8. Yang Lu#, Chang Su#, Ohimai Unoje, and Haoping Liu*. (2014) Quorum sensing controls hyphal initiation in Candida albicans through Ubr1-mediated protein degradation. PNAS111(5): 1975-80. Recommended by Faculty 1000. 9. Chang Su#, Yang Lu#, and Haoping Liu. (2013) Reduced TOR signaling sustains hyphal development in Candida albicans by lowering Hog1 basal activity. Molecular Biology of the Cell 24(3): 385-97. 10. Chang Su, Yandong Li, Yang Lu, and Jiangye Chen*. (2009) Mss11, a transcriptional activator, is required for hyphal development in Candida albicans. Eukaryotic Cell 8(11): 1780-91.