潘勤
教授
个人简介
教育背景 1996.9 - 2001.6,武汉大学医学部临床医学专业,学士 2001.7 - 2003.6,武汉大学基础医学院免疫学专业,硕士 2003.7 - 2006.6,武汉大学基础医学院病原生物学专业,博士 工作经历 2006.07 - 2011.12,武汉大学基础医学院,讲师 2010.10 - 2011.10,美国 University of Michigan, Medical school,访问学者 2011.12 - 2021.07,武汉大学基础医学院,副教授 2021.07 - 至今,武汉大学基础医学院,教授 获奖荣誉 2014 年,向近敏教育基金优秀青年教师奖 2018 年,教育部高等学校科学研究自然科学奖二等奖(人类重要胞内病原微生物感染、致病和免疫逃逸机制研究,3/9)
研究领域
结核菌诱导的免疫负调控机制,探索纠正负性调控增强机体免疫力的结核病防治新方法和策略
近期论文
1) Liu M#, Chen HY#, Luo L#, Wang Y, Zhang D, Song N, Wang FB, Li Q, Zhang XL, Pan Q*. Neutralization of IL-10 produced by B cells promotes protective immunity during persistent HCV infection in humanized mice. Eur J Immunol. 2020;50(9):1350-1361.) 2) Yuan C#, Qu ZL#, Tang XL, Liu Q, Wei L, Huang C, Pan Q*, Zhang XL*. Mycobacterium tuberculosis mannose-capped lipoarabinomannan induces IL-10-producing B cells and hinders CD4+Th1 immunity. iScience. 2019;11:13-30. 3) Zhou KL, Li X, Zhang XL, Pan Q*. Mycobacterial mannose-capped lipoarabinomannan: a modulator bridging innate and adaptive immunity. Emerg Microbes Infect. 2019;8(1):1168-1177. 4) Pan Q, Luo F, Liu M, Zhang XL*. Oligonucleotide aptamers: promising and powerful diagnostic and therapeutic tools for infectious diseases. J Infect. 2018 (2):83-98. 5) Tang XL, Yuan CH, Ding Q, Zhou Y, Pan Q*, Zhang XL*. Selection and identification of specific glycoproteins and glycan biomarkers of macrophages involved in Mycobacterium tuberculosis infection. Tuberculosis (Edinb). 2017 May;104:95-106. 6) Sun X#, Pan Q#, Yuan C, Wang Q, Tang XL, Ding K, Zhou X, Zhang XL*. A single ssDNA aptamer binding to ManLAM of BCG enhances immunoprotective effects against Tuberculosis. J Am Chem Soc. 2016;138(36):11680-9. doi: 10.1021/jacs.6b05357. 7) Pan Q, Li Q, Liu S, Ning N, Zhang X, Xu Y, Chang AE, Wicha MS*. Targeting Cancer Stem Cells Using Immunologic Approaches. Stem Cells. 2015;33(7):2085-92. (IF: 7.1) 8) Pan Q, Wang Q, Sun X, Xia X, Wu S, Luo F, Zhang XL*. Aptamer against mannose-capped lipoarabinomannan inhibits virulent Mycobacterium tuberculosis infection in mice and rhesus monkeys. Mol Ther. 2014;22(5):940-51.