学习经历 1997 年 - 2002 年，就读于武汉大学临床医学专业，获学士学位。 2002 年 - 2005 年，在武汉大学、北京 301 医院、第二炮兵总医院攻读病理生理学专业，获硕士学位。 2005 年 - 2008 年，于北京大学攻读药理学专业，获博士学位。 工作经历 2008 年 - 2010 年，在美国匹兹堡大学医学中心担任药理学博士后。 2011 年 - 至今，任职于武汉大学药学院药理学专业，先后担任副教授、教授。

神经精神疾病机制研究与靶标确证 麻精药品成瘾规避靶向新药研发 精准诊疗监测技术与产品研发 新药临床前评价、转化与临床研究

1.Zhu S, Chen P, Chen M, Ruan J, Ren W, Zhang X, Gao Y and Li Y *.(2020/01).Alcohol inhibits morphine/ cocaine reward memory acquisition and reconsolidation in rats.Psychopharmacology (Berl).2020 Apr;237(4):1043-1053. 2．Gao Y, Peng S, Wen Q, Zheng C, Lin J, Tan Y, Ma Y, Luo Y, Xue Y, Wu P, Ding Z, Lu L and Li Y * The mammalian target of rapamycin pathway in basolateral amygdala is critical for nicotine-induced behavioral sensitization. Int J Neuropsychopharmacol. 2014. 3. Lin J, Liu L, Wen Q, Zheng C, Gao Y, Peng S , Tan Y and Li, Y *. Rapamycin prevents drug seeking via disrupting reconsolidation of reward memory in rats. Int J Neuropsychopharma -col. 2014 Jan;17(1):127-36.Epub 2013 Oct 8. 4. Li YQ, Xue YX, He YY, Li FQ, Xue LF, Xu CM, Sacktor TC, Shaham Y, Lu L. Inhibition of PKMzeta in nucleus accumbens core abolishes long-term drug reward memory. J Neurosci. 2011 Apr 6;31(14):5436-46. 5. Li YQ, Li FQ, Wang XY, Wu P, Zhao M, Xu CM, Shaham Y, Lu L. Central amygdala ERK signaling pathway is critical to incubation of opiate craving. J Neurosci. 2008 Dec 3;28(49):13248-57. 6. Li YQ, Wang XY, Zhai HF, Zheng YQ, Zhang XY, Kosten T, Lu L.. Effects of early postnatal sibling deprivation on anxiety and vulnerability to cocaine in offspring rats. Psychopharmacology (Berl). 2008 Aug;199(2):245-53. 7. Li YQ, Wang XY, Zhai HF, Zhang XY, Kosten T, Lu L. Sex- and age-dependent effects of early postnatal sibling deprivation on spatial learning and memory in adult rats. Behav Brain Res. 2008 Jan 10;186(1):138-42. 8. Zhai H, Li YQ (co-first author), Wang X, Lu L.. Drug-induced alterations in extracellular signal-regulated kinase (ERK) signalling pathway: implications for reinforcement and reinstatement (review). Cell Mol Neurobiol. 2008 Feb;28(2):157-72. 9. Fang Q, Li FQ, Li YQ, Xue YX, He YY, Liu JF, Lu L, Wang JS. Cannabinoid CB(1) receptor antagonist rimonabant disrupts nicotine reward-associated memory in rats. Pharmacol Biochem Behav. 2011 Oct; 99(4):738-42. 10. Li FQ, Xue YX, Wang JS, Fang Q, Li YQ, Zhu WL, He YY, Liu JF, Xue LF, Shaham Y, Lu L. Basolateral amygdala Cdk5/p35 activity mediates cocaine rewarding memory. J Neurosci, 2010 Aug 4;30(31):10351-9. 11. Yu LL, Wang XY, Zhao M, Liu Y, Li YQ, Li FQ, Wang X, Xue YX, Lu L. Effects of cannabinoid CB1 receptor antagonist rimonabant in consolidation and reconsolidation of methamphetamine reward memory in mice. Psychopharmacology (Berl). 2009 Jun;204(2):203-11. 12. Wang XY, Zhao M, Ghitza UE, Li YQ, Lu L. Stress impairs reconsolidation of drug memory via glucocorticoid receptors in the basolateral amygdale. J Neurosci. 2008 May 21;28(21):5602-10. 13. Liu J, Li YQ , Ouyang JP et al. Protective effects of NADH on cardiac fibroblasts apoptosis induced by hydrazine. Med J Chin PLA. 2008. 33: 305-307. 14. Li YQ , Liu J, Ouyang JP , et al. The mechanism of the apoptosis of cardiac fibroblast induced by hydrazine. Chin J Aerospace Med, 2006.17: 176-179. 15. Li YQ , Liu J, Ouyang JP , et al. Effect of hydrazine on Proliferation and apoptosis of cardiac fibroblast. Medical Journal of Wuhan University. 2005. 26: 326-328.