李立家 照片

李立家

教授 博导

所属大学: 武汉大学

所属学院: 生命科学学院

邮箱:
ljli@whu.edu.cn

个人主页:
https://bio.whu.edu.cn/info/1500/9367.htm

个人简介

学习经历 1985 年 09 月 - 1989 年 07 月,就读于华中农业大学,生命科学与技术学院微生物专业,获学士学位。 1989 年 09 月 - 1992 年 07 月,在华中农业大学,生命科学与技术学院微生物专业深造,获硕士学位。 1995 年 09 月 - 1998 年 07 月,于武汉大学,生命科学学院遗传专业攻读,获博士学位。 主要工作经历与任职情况 1992 年 07 月 - 1994 年 07 月,任武汉大学生命科学学院助教。 1994 年 07 月 - 2001 年 11 月,担任武汉大学生命科学学院讲师。 1998 年 11 月 - 2001 年 09 月,在美国内布拉斯加林肯大学从事博士后研究工作。 2001 年 11 月 - 2005 年 11 月,晋升为武汉大学生命科学学院副教授。 2006 年 03 月 - 2006 年 12 月,在美国爱尔瓦州立大学进行合作进修研究。 2005 年 11 月 - 至今,担任武汉大学生命科学学院教授。

研究领域

细胞遗传与表观遗传

近期论文

最近发表的论文(#并列第一作者,*通讯作者): 1) Jiaqi Hou, Xueke Zheng, Ruifei Ren, Qipeng Shi, Huangzhuo Xiao, Zhenfei Chen, Mengxia Yue, Yequn Wu, Haoli Hou, Lijia Li*. (2022) The histone deacetylase 1/GSK3/SHAGGY-like kinase 2/BRASSINAZOLE-RESISTANT 1 module controls lateral root formation in rice. Plant Physiology, 189: 858–873. 2) Hong Zhou#, Yapei Wang#, Qing Wang, Le Li, Yan Hu, Yequn Wu, Mayank Gautam, Lijia Li*. (2021) R-loops mediate transcription-associated formation of human rDNA secondary constrictions. Journal of cellular biochemistry, 22 (10): 1517-1533. 3) Mengxia Yue, Mayank Gautam, Zhenfei Chen, Jiaqi Hou, Xueke Zheng, Haoli Hou, Lijia Li*. (2021) Histone acetylation of 45S rDNA correlates with disrupted nucleolar organization during heat stress response in Zea mays L.. Physiologia plantarum, 172 (4): 2079-2089. 4) Jiaqi Hou, Ruifei Ren, Huangzhuo Xiao, Zhenfei Chen, Jinfu Yu, Haorui Zhang, Qipeng Shi, Haoli Hou, Shibin He*, Lijia Li*. (2021) Characteristic and evolution of HAT and HDAC genes in Gramineae genomes and their expression analysis under diverse stress in Oryza sativa. Planta, 253(3):72. 5) Hong Zhou#, Le Li#, Qing Wang#, Yan Hu, Weiwei Zhao, Mayank Gautam, Lijia Li*. (2020) H3K9 demethylation-induced R-Loop accumulation is linked to disorganized nucleoli. Frontiers in Genetics, 11:43. 6) Hao Zhang, Mengxia Yue,Xueke Zheng,Mayank Gautam,Shibin He, Lijia Li*. (2018) The role of promoter-associated histone acetylation of haem oxygenase-1 (HO-1) and giberellic acid-stimulated like-1 (GSL-1) genes in heat-induced lateral root primordium inhibition in maize. Frontiers in Plant Science, 9: 1520. 7) Haoli Hou, Xueke Zheng, Hao Zhang, Mengxia Yue, Yan Hu, Hong Zhou, Qing Wang, Chengshen Xie, Pu Wang, and Lijia Li*. (2017) Histone deacetylase is required for GA-induced programmed cell death in maize aleurone layers. Plant Physiology, 175(3): 1484-1496. 8) Xueke Zheng, Haoli Hou, Hao Zhang, Mengxia Yue, Yan Hu, Lijia Li*. (2017) Histone acetylation is involved in GA-mediated 45S rDNA decondensation in maize aleurone layers. Plant Cell Report, 31(1): 115-123. 9) Qing Wang, Pu Wang, Hong Zhou, Yan Hu, Chengshen Xie, Fei Gao, Ningjie Ma, Haoli Hou, Hao Zhang, Lijia Li*. (2017) 5-Azacytidine specifically inhibits the NIH-3T3 PCD process induced by TNF-alpha and cycloheximide via affecting BCL-XL. Journal of Cellular Biochemistry, 119(2):1501-1510. 10) Fei Gao, Ningjie Ma, Hong Zhou, Qing Wang, Hao Zhang, Pu Wang, Haoli Hou, Huan Wen, Lijia Li*. (2016) Zinc oxide nanoparticles-induced epigenetic change and G2/M arrest are associated with apoptosis in human epidermal keratinocytes. International Journal of Nanomedicine, 11: 3859–3874. 11) Pu Wang, Hao Zhang, Haoli Hou, Qing Wang, Yingnan Li, Yan Huang, Liangfu Xie, Fei Gao, Shibin He, Lijia Li*. (2016) Cell cycle arrest induced by inhibitors of epigenetic modifications in maize (Zea mays) seedling leaves: characterization of the process and possible mechanisms involved. New Phytologist, 221(2): 646–657. 12) Haoli Hou, Pu Wang, Hao Zhang, Huan Wen, Fei Gao, Ningjie Ma, Qing Wang, Lijia Li*. (2015) Histone acetylation is involved in gibberellin-regulated sodCp gene expression in maize aleurone layers. Plant and Cell Physiology, 56(11): 2139-2149. 13) Pu Wang, Lin Zhao, Haoli Hou, Hao Zhang, Yan Huang, Yapei Wang, Hui Li, Fei Gao, Shihan Yan, Lijia Li*. (2015) Epigenetic changes are associated with programmed cell death induced by heat stress in seedling leaves of Zea mays. Plant and Cell Physiology, 56(5): 965-976. 14) Shibin He#, Xu Yu#, Xiangwu Wang, Junjun Tan, Shihan Yan, Pu Wang, Bi-Hai Huang, Zhi-Ling Zhang*, Lijia Li*. (2014) Fast magnetic isolation of simple sequence repeat markers in microfluidic channels. Lab on a Chip, 14: 1410-1414. 15) Shihan Yan, Lin Zhao, Hui Li, Qi Zhang, Junjun Tan, Min Huang, Shibin He, Lijia Li*. (2013) Single-walled carbon nanotubes selectively influence maize root tissue development accompanied by the change in the related gene expression. Journal of Hazardous Materials, 246– 247: 110– 118. 16) Shibin He#,Bi-Hai Huang#,Junjun Tan,Qing-Ying Luo,Yi Lin,Jun Li,Yong Hu,Lu Zhang,Shihan Yan,Qi Zhang,Dai-Wen Pang*,Lijia Li*. (2011) One-to-one quantum dot-labeled single long DNA probes. Biomaterials, 32(23): 5471-5477.