冯勇 照片

冯勇

副教授 硕导

所属大学: 武汉大学

所属学院: 基础医学院

邮箱:
yongfeng@whu.edu.cn

个人主页:
https://wbm.whu.edu.cn/info/1350/5969.htm

个人简介

教育背景: 1995.9 - 1999.6,武汉大学生命科学学院生物化学专业,本科 2002.9 - 2007.6,武汉大学生命科学学院微生物学专业,硕博连读 工作经历: 2007.08 - 2009.11,武汉大学基础医学院病原生物学系,助教 2009.11 - 2012.11,武汉大学基础医学院病原生物学系,讲师 2010.02 - 2012.01,美国明尼苏达大学,博士后访问学者 2012.11 - 至今,武汉大学基础医学院病原生物学系,副教授 2017.03 - 2018.01,湖北崇阳经济开发区管委会,副主任(挂职) 2018.06 - 2019.06,科技部中国生物技术发展中心,借调 2021.10 - 至今,武汉大学基础医学院医学微生物学教研室,副主任

研究领域

病毒感染与致病机制

1. HIV感染与宿主免疫缺陷的表现、调控及分子机制。 2. 逆转录病毒基因组整合调控分子机制。 3. 病原微生物感染的检测诊断,创新病原微生物感染的检测与诊断方法。

近期论文

1. Xie, L., Ju, Z., Zhong, C., Wu, Y., Zan, Y., Hou, W*., and Feng, Y*. (2021) GTPase Activity of MxB Contributes to Its Nuclear Location, Interaction with Nucleoporins and Anti-HIV-1 Activity. Virologica Sinica 36(1): 85-94. 2. Xie, L., Chen, L., Zhong, C., Yu, T., Ju, Z., Wang, M., Xiong, H., Zeng, Y., Wang, J., Hu, H., Hou, W*., and Feng, Y*. (2020) MxB impedes the NUP358-mediated HIV-1 pre-integration complex nuclear import and viral replication cooperatively with CPSF6. Retrovirology 17, 16 3. Guo, W., Ming, F., Feng, Y., Zhang, Q., Mo, P., Liu, L., Gao, M., Tang, W., and Liang, K. (2020) Patterns of HIV and SARS-CoV-2 co-infection in Wuhan, China. Journal of the International AIDS Society 23, e25568 4. Liu, R., Han, H., Liu, F., Lv, Z., Wu, K., Liu, Y., Feng, Y*., and Zhu, C. (2020) Positive rate of RT-PCR detection of SARS-CoV-2 infection in 4880 cases from one hospital in Wuhan, China, from Jan to Feb 2020. Clinica chimica acta; international journal of clinical chemistry 505, 172-175 5. Han, H., Xie, L., Liu, R., Yang, J., Liu, F., Wu, K., Chen, L., Hou, W., Feng, Y*., and Zhu, C. (2020) Analysis of heart injury laboratory parameters in 273 COVID-19 patients in one hospital in Wuhan, China. Journal of medical virology 92, 819-823 6. Yu, T., Ju, Z., Luo, M., Hu, R., Teng, Y., Xie, L., Zhong, C., Chen, L., Hou, W*., Xiong, Y*., and Feng, Y*. (2019) Elevated expression of miR-146a correlates with high levels of immune cell exhaustion markers and suppresses cellular immune function in chronic HIV-1-infected patients. Scientific reports 9, 18829 7. Teng, Y., Luo, M., Yu, T., Chen, L., Huang, Q., Chen, S., Xie, L., Zeng, Y., Luo, F., Xiong, H., Liu, Y., Hou, W*., and Feng, Y*. (2019) CRISPR/Cas9-mediated deletion of miR-146a enhances antiviral response in HIV-1 infected cells. Genes and immunity 20, 327-337 8. Li, N., Luol, F., Chen, Q. Z., Zhu, N., Wang, H., Xie, L. L., Xiong, H. R., Yue, M., Zhang, Y., Feng, Y*., and Hou, W*. (2019) IFN-lambda s inhibit Hantaan virus infection through the JAK-STAT pathway and expression of Mx2 protein. Genes and immunity 20, 234-244 9. Huang, Q., Chen, L., Luo, M., Lv, H., Luo, D., Li, T., Huang, S., Xie, L., Teng, Y., Liu, Z., Luo, F., Xiong, H., Zeng, Y., Hou, W*., and Feng, Y*. (2018) HIV-1-Induced miR-146a Attenuates Monocyte Migration by Targeting CCL5 in Human Primary Macrophages. AIDS research and human retroviruses 34, 580-589 10. Li, L., Feng, H., Da, Q., Jiang, H., Chen, L., Xie, L., Huang, Q., Xiong, H., Luo, F., Kang, L., Zeng, Y., Hu, H., Hou, W*., and Feng, Y*. (2016) Expression of HIV-encoded microRNA-TAR and its inhibitory effect on viral replication in human primary macrophages. Arch Virol 161, 1115-1123