陈璞 照片

陈璞

教授 博导

所属大学: 武汉大学

所属学院: 基础医学院

邮箱:
puchen@whu.edu.cn

个人主页:
https://wbm.whu.edu.cn/info/1350/5924.htm

个人简介

教育背景: 2001 - 2005,华中科技大学光电子工程系,光信息科学与技术专业,理学学士 2006 - 2011,华中科技大学生物医学工程系,生物医学工程专业,工学博士 工作经历: 2011 - 2014,哈佛大学医学院哈佛麻省理工健康科学技术部、布莱根妇女医院,博士后研究员 2014 - 2016,斯坦福大学医学院金丝雀癌症早期诊断中心,博士后研究员 2016 - 至今,武汉大学基础医学院生物医学工程系,教授 获奖荣誉: 2024 年 11 月,《声与水的共舞》获第七届全国科学实验展演汇演二等奖(陈璞、尚佳、曹瀚文、刘云南) 2024 年 7 月,《智能辅助生殖芯片》获第九届全国大学生生物医学工程创新设计竞赛一等奖(陈司晗、赵稳) 2024 年 9 月,《生物组装》获 2024 生物医学工程科普微视频大赛一等奖(陈璞、尚佳、樊宇航、赵稳) 2024 年 9 月,黄雪梅获 2024 中国生物医学工程大会暨创新医疗峰会 S9 组织工程与再生医学分会场优秀论文竞赛三等奖 2024 年 9 月,陈涛获 2024 中国生物医学工程大会暨创新医疗峰会 S9 组织工程与再生医学分会场优秀论文竞赛三等奖 2024 年 10 月 20 日,黄雪梅获 2024 微生理系统国际研讨会暨第七届类器官与器官芯片学术会议青年优秀论文奖 2024 年 10 月 20 日,沈慜获 2024 微生理系统国际研讨会暨第七届类器官与器官芯片学术会议优秀墙报奖 2024 年 12 月,Tao Chen 的《Human Brain Organoid -based Corticogenesis on a Chip for Modeling ZlKV-induced Malformations of Cortical Development》获 2024 Termis-AP students Webinar Presentation Contest 银奖 2024 年 12 月,Xuemei Huang 的《Trans-organoid co-differentiation (TOCO) chip for constructing heart-brain developmental model》获 2024 Termis-AP students Webinar Presentation Contest 银奖 2024 年 12 月,Lili Zhu 的《Human Blood Brain Barrier-Brain Organoid on a Chip for Modeling Neuroinflammation-induced Barrier Dysfunction》获 2024 Termis-AP students Webinar Presentation Contest 铜奖

研究领域

组织工程与再生医学、干细胞与人工器官、基于微流控芯片和微声光机电技术的体外诊断

组织工程与器官制造、类器官芯片、声学生物组装、人类多能干细胞

近期论文

[1] S. Chen, L. Zhu, J. Wang, S. Jiang, Y. Fan, W. Zhao, Z. Wang, Q. Zhou, Y. Chen and P. Chen*, Soft-lithographically defined template for arbitrarily patterned acoustic bioassembly. Biofabrication (2024), DOI 10.1088/1758-5090/ad9637 [2] S. Chen, J. Chen, Z. Qin, J. Wang, Y. Wang, R. Liu, W. Zhao, M. Zhang, Y. Zhang*, M. Luo* & P. Chen*, Microfluidic thermotaxic selection of highly motile sperm and in vitro fertilization. Bio-Design and Manufacturing (2024), 7, 687–700. https://doi.org/10.1007/s42242-024-00306-1 [3] Y. Yang, M. Ni, R. Zong, M. Yu, Y. Sun, J. Li, P. Chen*, C. Li*, Targeting Notch1-YAP Circuit Reprograms Macrophage Polarization and Alleviates Acute Liver Injury in Mice, Cell. Mol. Gastroenterol. Hepatol. 15(5) (2023) 1085-1104. [4] Y. Zhou, H. Qiao, F. Xu, W. Zhao, J. Wang, L. Gu, P. Chen*, M. Peng*, Bioengineering of a human physiologically relevant microfluidic blood-cerebrospinal fluid barrier model, Lab Chip DOI: 10.1039/D3LC00131H (2023). [5] J. Wang, H. Qiao, Z. Wang, W. Zhao, T. Chen, B. Li, L. Zhu, S. Chen, L. Gu, Y. Wu, Z. Zhang, L. Bi, P. Chen*, Rationally Design and Acoustically Assemble Human Cerebral Cortex-like Microtissues from hiPSC-derived Neural Progenitors and Neurons, Adv Mater DOI: 10.1002/adma.202210631 (2023) [6] N. Liu#, L. Gu, Z. Wang, J. Wang, P. Chen*, Emerging Acoustic Assembly for 3D Biofabrication, in: U. Demirci, R.E. Assal, P. Chen (Eds.) Emerging Technologies in Biophysical Sciences: A World Scientific Reference, World Scientific Publishing Co Pte Ltd, Singapore, 2023, p. 492. [7] j.L. Gu#, S.S. Jiang, d.X. Xu, b.J. Wang, F. Xu, H. Fan, J. Shang, K. Liu, U. Demirci*, P. Chen*, Size- and density-dependent acoustic differential bioassembly of spatially-defined heterocellular architecture, Biofabrication (2022), 15:015019 [8] S. Jiang#, F. Xu, M. Jin, Z. Wang, X. Xu, Y. Zhou, J. Wang, L. Gu, H. Fan, Y. Fan, Z. Zhou, C. Li, P. Chen*, Development of a high-throughput micropatterned agarose scaffold for consistent and reproducible hPSC-derived liver organoids, Biofabrication (2022), 15:015006 [9] X. Xu#, S. Jiang#, L. Gu, B. Li, F. Xu, C. Li, P. Chen*, High-throughput bioengineering of homogenous and functional human-induced pluripotent stem cells-derived liver organoids via micropatterning technique, Frontiers in Bioengineering and Biotechnology (2022), 10:937595. [10] H. Qiao#, M. Gu, J. Shang, W. Zhao, Z. Wang, N. Liu, B. Li, Y. Zhou, Y. Wu*, P. Chen*, Herpes simplex virus type 1 infection leads to neurodevelopmental disorder-associated neuropathological changes, PLoS Pathog. (2020), 22;16(10):e1008899 [11] Y. Zhao#, U. Demirci*, Y. Chen*, P. Chen*, Multiscale brain research on a microfluidic chip, Lab Chip (2020), 20:1531-1543 [12] H. Fan#, U. Demirci*, P. Chen*, Emerging organoid models: leaping forward in cancer research, J Hematol Oncol. (2019), 12(1):142 [13] T. Ren#, P. Chen, L. Gu, M.G. Ogut, U. Demirci*, Soft Ring‐Shaped Cellu‐Robots with Simultaneous Locomotion in Batches, Adv. Mater. (2019), 32(8):e1905713