学习简历 2001 年 09 月 - 2005 年 06 月，就读于中南大学制药工程专业，获学士学位。 2007 年 09 月 - 2012 年 06 月，在中国科学院上海药物研究所攻读天然药物化学（海洋天然产物）专业，获博士学位。 2011 年 11 月 - 2012 年 05 月，作为 Ph.D. student 在意大利那不勒斯腓特烈二世大学（University of Napoli Federico II, Napoli, Italy）学习。 工作经历 2005 年 07 月 - 2007 年 08 月，先后在新和成股份有限公司、药明康德新药开发有限公司工作。 2012 年 07 月 - 2014 年 03 月，任武汉生物工程学院医药学院讲师。 2014 年 04 月 - 至今，担任武汉大学药学院副教授。 2016 年 01 月 - 2018 年 01 月，在夏威夷大学从事博士后研究工作。

[1] 药用植物活性天然产物及其活性研 [2] 植物内生真菌、海洋微生物活性化学成分研究 [3] 抗肿瘤、抗菌、抗炎活性天然产物的发现、修饰、构效关系及机理研究

[1] Y.-S. Cai, Y.-W. Guo* and K. Krohn. Structure, bioactivities, biosynthetic relationships and chemical synthesis of the spirodioxynaphthalenes. Natual Product Reports, 2010, 27, 1840-1870. (SCI一区, IF: 11.876) [2] Y.-S. Cai, T. Kurtán, Z.-H. Miao, A. Mándi, I. Komáromi, H.-L. Liu, J. Ding, and Y.-W. Guo*. Palmarumycins BG1-BG7 and preussomerin BG1: establishment of their absolute configurations using theoretical calculations of electronic circular dichroism spectra. The Journal Organic Chemistry. 2011, 76, 1821-1830. (SCI二区TOP, IF: 4.335) [3] Y.-S. Cai, L.-G. Yao, A. Di Pascale, C. Irace, E. Mollo, O. Taglialatela-Scafati, Y.-W. Guo*. Polyoxygenated diterpenoids of the eunicellin-type from the Chinese soft coral Cladiella krempfi. Tetrahedron 2013, 69, 2214-2219. (SCI三区, IF: 2.233) [4] L.-F. Liang#, T. Wang#, Y.-S. Cai#, W.-F. He, P. Sun, Y.-F. Li, Q. Huang, O. Taglialatela-Scafati*, H.-Y. Wang*, Y.-W. Guo*. Brominated polyunsaturated lipids from the Chinese sponge Xestospongia testudinaria as a new class of pancreatic lipase inhibitors. European Journal of Medicinal Chemistry. 2014, 79, 290-297. (SCI一区, IF: 5.572) [5] Z.-F. Zhou, M. Menna, Y.-S. Cai, and Y.-W. Guo*. Polyacetylenes of marine origin: chemistry and bioactivity. Chemical Reviews, 2015, 115 (3), 1543–1596. (SCI一区, IF: 52.758) [6] Y.-S. Cai, A. M. Sarotti, D. Gündisch, T. P. Kondratyuk, J. M. Pezzuto, J. Turkson, S. Cao*. Heliotropiumides A and B, new phenolamides with N-carbamoyl putrescine moiety from Heliotropium foertherianum collected in Hawaii and their biological activities. Bioorganic & Medicinal Chemistry Letters, 2017, 27, 4630-4634. (SCI三区, IF: 2.572) [7] S.-Y. Zhou, T.-L. Zhou, G. Qiu, X. Huan, Z.-H. Miao, S.-P. Yang, S. Cao, F. Fan, Y.-S. Cai*. Three new cytotoxic monoterpenoid bisindole alkaloids from Tabernaemontana bufalina. Planta Medica, 2018, 84, 1127-1133. (SCI三区, IF: 2.687) [8] S.-Y. Zhou, F. Fan, J.-Z. Sun, Z. Guo, W.-T. Sun, L. Chen, Q.-Q. Tang, G. Qiu, S.-P. Yang, J. Yu, Y.-S. Cai*. Cytotoxic alkaloids from the fruits and seeds of Alangium salviifolium (L.f.) Wangerin. Phytochemistry Letters 2018, 26, 195-198. (SCI四区, IF: 1.459) [9] Y.-S. Cai, J.-Z. Sun, Q.-Q. Tang, F. Fan & Y.-W. Guo*. Acanthiline A, a pyrido[1,2-a]indole alkaloid from Chinese mangrove Acanthus ilicifolius. Journal of Asian Natural Products Research, 2018, 20(11), 1088-1092. (SCI四区, IF: 1.345) [10] Y.-S. Cai*, A. M. Sarotti, T.-L. Zhou, R. Huang, G. Qiu, C. Tian, Z.-H. Miao, A. Mándi, T. Kurtán, S. Cao,* S.-P. Yang*. Flabellipparicine, a flabelliformide-apparicine-type bisindole alkaloid from Tabernaemontana divaricata. Journal of Natural Products, 2018. 81, 1976-1983. (SCI二区TOP, IF:3.779) [11] Y.-S. Cai,* C. Wang, C. Tian, W.-T. Sun, L. Chen, D. Xiao, S.-Y. Zhou, G. Qiu, J. Yu, K. Zhu, and S.-P. Yang* Octahydro-protoberberine and protoemetine-type alkaloids from the stems of Alangium salviifolium and their cytotoxicity. Journal of Natural Products, 2019, 82, 2645-2652. (SCI二区TOP, IF:3.779) [12] Y.-S. Cai,# Z. Wu,# J.-R. Wang, X.-Q. Zheng, J. Xu, G. Qiu, J. Yu*. Spiroalanfurantones A-D, four eudesmanolide-furan sesquiterpene adducts with a pentacyclic 6/6/5/5/5 skeleton from Inula helenium. Organic Letters, 2019, 21, 9478-9482. (SCI一区, IF: 6.091) [13] Y.-S. Cai,# Z. Wu,# X.-Q. Zheng, C. Wang, J.-R. Wang,c X.-X. Zhang, G. Qiu, K. Zhu, S. Cao and J. Yu*. Spiroalanpyrroids A and B, sesquiterpene alkaloids with a unique spiro-eudesmanolide–pyrrolizidine skeleton from Inula helenium. Organic Chemistry Fronters, 2020, 7, 303-309. (SCI一区, IF: 5.155) [14] Z. Wu,# Y.-S. Cai,# R. Yuan, Q. Wan, D. Xiao, J. Lei, J. Yu* Bioactive pterocarpans from Trigonella foenum-graecum L. Food Chemistry. 2020, 313, 126092/1-7. (SCI一区, IF: 6.306) [15] C.-K. Tian, R.-Y. Yuan,* Y.-X. Wang, L. Chen, Z. Wu, L. Liu, Y.-S. Cai* Two new guaiane sesquiterpenes from the fruiting bodies of Lactarius Deliciosus. J. Asian Nat. Prod. Res. 2020, DOI: 10.1080/10286020.2019.1695781. (SCI四区, IF: 1.345) [16] Y.-S. Cai, J. Xu, M. Chen, D. Wang, Y. Yang, A. Manavalan, X. Wu, Y. Liu,* S. Cao* Compound analysis of Jing Liqueur and nrf2 activation by Jing liqueur-one of the most popular beverages in China. Beverages 2020, 6 (1), 1-18. (SCIE) [17] Y.-S. Cai, W.-X. Cui, W. Tang, Y.-W. Guo*; Uncommon terpenoids with anti-inflammatory activity from the Hainan soft coral Sinularia tumulosa. Bioorganic Chemistry 2020, 104, 104167/1-8. (SCI二区TOP, IF: 4.831)