教育背景 1999/9–2003/7，华中师范大学，应用化学，学士 2003/9–2009/6，南开大学，化学生物学，博士

工作经历 2013/7-至今，天津医科大学，药学院，讲师 2010/1-2012/1，美国加州大学旧金山分校药学院，博士后

生物大分子药物的递送系统研究

中国化学会会员

1.Lu Sun, Shuping Xie, Jing Qi, Ergang Liu, Di Liu, Quan Liu, Sunhui Chen, Huining He*, Victor C. Yang*, Cell-Permeable, MMP-2 Activatable, Nickel Ferrite and His-Tagged Fusion Protein Self-Assembled Fluorescent Nanoprobe for Tumor Magnetic-Targeting and Imaging. ACS Applied Materials & Interfaces, 2017, doi: 10.1021/acsami.7b12918. (IF: 7.504)

2.Zhili Yu1, Junxiao Ye1, Xing Pei, Lu Sun, Ergang Liu, Jianxin Wang, Yongzhuo Huang, Seung Jin Lee, Huining He*. Improved Method for Synthesis of Low Molecular Weight Protamine-siRNA Conjugate. Acta Pharmaceutica Sinica B. Accepted.

3.Sunhui Chen.1; Qiuling Liang1; Ergang Liu,Yu, Zhili Yu, Lu Sun, Junxiao Ye, Meong Cheol Shin, Jianxin Wang, Huining He*, Curcumin/Sunitinib Co-Loaded Bsa-Stabilized Spios for Synergistic Combination Therapy for Breast Cancer. Journal of Materials Chemistry B, 2017, 5 (22): 4060-4072. (IF: 4.543)

4.Pengwei Zhang, Junxiao Ye, Ergang Liu, Lu Sun, Jiacheng Zhang, Seung-Jin Lee, Junbo Gong*, Huining He* and Victor C. Yang*. Aptamer-coded DNA nanoparticles for targeted doxorubicin delivery using pH-sensitive spacer. Frontiers of Chemical Science and Engineering, 2017, (2):1-8. (IF:1.712)

5.Sunhui Chen1, Qiuling Liang1, Shuping Xie, Ergang Liu, Zhili Yu, Lu Sun, Meong Cheol Shin, Seung Jin Lee, Huining He*, Victor C. Yang*, Curcumin Based Combination Therapy for Anti-breast Cancer: From in vitro Drug Screening to in vivo Efficacy Evaluation Frontiers of Chemical Science and Engineering, 2016, 10(3):383-388. (IF:1.712)

6.Huining He1, Lu Sun1, Junxiao Ye, Ergang Liu, Sunhui Chen, Qiuling Liang, Meong Cheol Shin, Victor C. Yang*, Enzyme-Triggered, Cell Penetrating Peptide-Mediated Delivery of Anti-Tumor Agents, Journal of Controlled Release, 2016, 240:67–76. (IF:7.786)

7.Lu Sun, C.C. Wang*. The structural basis of localizing polo-like kinase to the flagellum attachment zone in Trypanosoma brucei. PLoS One, 2011, 6(11):e27303. (IF:2.806)

8.Xiaohong Qin1, Lu Sun1, Xin Wen, Xue Yang, Ying Tan, Hao Jin, Qiongyao Cao, Weihong Zhou, Zhen Xi*, Yuequan Shen*. Structural insight into unique properties of protoporphyrinogen oxidase from Bacillus subtilis. Journal of Structural Biology, 2010, 170(1):76-82. (IF:2.767)

9.Lu Sun, Xin Wen, Ying Tan, Heyang Li, Xing Yang, Yuefang Zhao, Baifan Wang, Qiongyao Cao, Congwei Niu, Zhen Xi*. Site-directed mutagenesis and computational study of the Y366 active site in Bacillus subtilis protoporphyrinogen oxidase. Amino Acids, 2009, 37(3):523-530. (IF:3.173)

10.Long Yi1, Heyang Li1, Lu Sun, Liangliang Liu, Caihong Zhang, Zhen Xi*. A highly sensitive fluorescence probe for fast thiol-quantification assay of glutathione reductase. Angewandte Chemie International Edition, 2009, 48(22):4034-4037. (IF:11.994)

11.Ying Tan1, Lu Sun1, Zhen Xi*, Guangfu Yang, Dongqing Jiang, Xiuping Yan, Xing Yang, Heyang Li. A capillary electrophoresis assay for recombinant Bacillus subtilis protoporphyrinogen oxidase. Analytical Biochemistry, 2008, 383(2):200-204 (IF:2.334)