吴辉，工学博士，副教授。现任中国轻工业生物基材料工程重点实验室副主任，中国化工学会生物化工专委会青年学者工作委员会委员，生物反应器工程国家重点实验室固定人员。教育部“霍英东青年教师基金”获得者（2018）。2004年毕业于南京工业大学生物工程系，获工学学士学位。2009年毕业于华东理工大学发酵工程专业，获工学博士学位。同年进入中科院上海生命科学研究院植物生理生态研究所从事博士后研究工作。2011年来到誉有“南方的哈佛”之称的美国莱斯大学生物工程系从事博士后研究工作。2014年9月引进华东理工大学生物工程学院，入选华东理工大学“青年英才培育计划”（2018 A类、2015）， 生物工程学院青年教师扶持计划（2015）、“远志计划”（2017）等。近年来以第一作者或通讯作者在Metabolic Engineering，Biotechnology Advances，ACS Synthetic Biology，Biotechnology and Bioengineering，Applied and Environmental Microbiology等本领域重点期刊上发表SCI收录论文30余篇。

1．微生物代谢工程生产平台化合物和生物活性物质 2．合成生物学中“代谢晶体管”研究及其应用 3. 基于微生物电化学合成的代谢工程与合成生物学

1．Jiapeng Tang, Zhenqing Qian, Hui Wu*. 2018. Enhancing cordycepin production in liquid static cultivation of Cordyceps militaris by adding vegetable oils as the secondary carbon source. Bioresource Technology. 268:60-67. (IF=5.807, JCR Q1)

2．Bing Huang, Hao Yang, Guochen Fang, Xing Zhang, Hui Wu*, Zhimin Li*, Qin Ye. 2018. Central pathway engineering for enhanced succinate biosynthesis from acetate in Escherichia coli. Biotechnology and Bioengineering. 115:943-954. (*Co-corresponding) (IF=3.952, JCR Q1)

3．Wei Li#, Hui Wu#, Mai Li, Ka-Yiu San*. 2018. Effect of NADPH availability on free fatty acid production in E. coli. Biotechnology and Bioengineering. 115:444-452. (#First two authors contributed to this paper equally) (IF=3.952, JCR Q1)

4．Han Liu, Guochen Fang, Hui Wu*, Zhimin Li*, Qin Ye. 2018. L-cysteine production in Escherichia coli based on rational metabolic engineering and modular strategy. Biotechnology Journal. 13:e1700695. (*Co-corresponding) (IF=3.507, JCR Q2)

5. Feng Li#, Yuanxiu Li#, Liming Sun, Xiaoli Chen, Xingjuan An, Changji Yin, Yingxiu Cao, Hui Wu, Hao Song*. 2018. Modular engineering intracellular NADH regeneration boosts extracellular electron transfer of Shewanella oneidensis MR-1. ACS Synthetic Biology. 7(3):885-895. (IF=5.316, JCR Q1)

6．Qing Li#, Bing Huang#, Qiaofei He, Jingxian Lu, Xun Li, Zhimin Li, Hui Wu*, Qin Ye. 2018. Production of succinate from simply purified crude glycerol by engineered Escherichia coli using two-stage fermentation. Bioresources and Bioprocessing. 5:41. (#First two authors contributed to this paper equally)

7. Jiaqi Jiang, Bing Huang, Hui Wu*, Zhimin Li*, Qin Ye. Efficient 3-hydroxypropionic acid production from glycerol by metabolically engineered Klebsiella pneumoniae. Bioresources and Bioprocessing. 5:34. (*Co-corresponding)

8．Qing Li, Bing Huang, Hui Wu*, Zhimin Li, Qin Ye. 2017. Efficient anaerobic production of succinate from glycerol in engineered Escherichia coli by using dual carbon sources and limiting oxygen supply in preceding aerobic culture. Bioresource Technology. 231: 75-84. (IF=5.807, JCR Q1)

9．Xing Zhang#, Hui Wu#, Bing Huang, Zhimin Li*, Qin Ye. 2017. One-pot synthesis of glutathione by a two-enzyme cascade using a thermophilic ATP regeneration system. Journal of Biotechnology. 241:163-169. (# First two authors contributed to this paper equally) (IF=2.533, JCR Q2)

10．Qing Li#, Hui Wu#, Zhimin Li, Qin Ye*. 2016. Enhanced succinate production from glycerol by engineered Escherichia coli strains. Bioresource Technology. 218:217-223. (# First two authors contributed to this paper equally) (IF=5.807, JCR Q1)

11．Yunjie Li, Bing Huang, Hui Wu*, Zhimin Li*, Qin Ye, Yi-Heng Percival Zhang. 2016. Production of succinate from acetate by metabolically engineered Escherichia coli. ACS Synthetic Biology. 5:1299-1307. (*Co-corresponding) (IF=5.316, JCR Q1)

12．Jianhua Yang, Wei Li, Dezheng Wang, Hui Wu*, Zhimin Li*, Qin Ye. 2016. Characterization of bifunctional L-glutathione synthetases from Actinobacillus pleuropneumoniae and Actinobacillus succinogenes for efficient glutathione biosynthesis. Applied Microbiology and Biotechnology. 100(14): 6279-6289. (*Co-corresponding) (IF=3.340, JCR Q2)

13．Jing Zhang, Cong Quan, Cheng Wang, Hui Wu*, Zhimin Li*, Qin Ye. 2016. Systematic manipulation of glutathione metabolism in Escherichia coli for improved glutathione production. Microbial Cell Factories. 15:38. (*Co-corresponding) (IF=3.831, JCR Q1)

14．Zhuan Cheng, Jiaqi Jiang, Hui Wu, Zhimin Li*, Qin Ye. 2016. Enhanced production of 3-hydroxypropionic acid from glucose via malonyl-CoA pathway by engineered Escherichia coli. Bioresource Technology. 200:897-904. (IF=5.807, JCR Q1)

15．Dezheng Wang, Cheng Wang, Hui Wu*, Zhimin Li*, Qin Ye. 2016. Glutathione production by recombinant Escherichia coli expressing bifunctional glutathione synthetase. Journal of Industrial Microbiology and Biotechnology. 43:45-53. (*Co-corresponding) (IF=3.103, JCR Q2)

16．Qin Ye*, Zhimin Li, Hui Wu. 2016. Principle and performance of gas self-inducing reactors and applications to biotechnology. Advances in Biochemical Engineering/Biotechnology. 152:1-33. (IF=2.795, JCR Q2)

17．Cheng Wang, Jing Zhang, Hui Wu*, Zhimin Li*, Qin Ye. 2015. Heterologous gshF gene expression in various vector systems in Escherichia coli for enhanced glutathione production. Journal of Biotechnology. 214:63-68. (*Co-corresponding). (IF=2.533, JCR Q2)

18．Hui Wu, Leepika Tuli, George N. Bennett, Ka-Yiu San*. 2015. Metabolic transistor strategy for controlling electron transfer chain in Escherichia coli. Metabolic Engineering. 28: 159-168. (IF=7.674, JCR Q1)

19．Hui Wu, George N. Bennett, Ka-Yiu San*. 2015. Metabolic control of respiratory levels in coenzyme Q biosynthesis-deficient Escherichia coli strains leading to fine-tune aerobic lactate fermentation. Biotechnology and Bioengineering. 112(8):1720-1726. (IF=3.952, JCR Q1)

20．Hui Wu, Jane Lee, Mukund Karanjikar, Ka-Yiu San*. 2015. Simultaneous utilization of glucose and mannose from woody hydrolysate for free fatty acid production by metabolically engineered Escherichia coli. Bioresource Technology. 185: 431-435. (IF=5.807, JCR Q1)

21．Dan Wang, Hui Wu, Chandresh Thakker, Jared Beyersdorf, George N Bennett, Ka-Yiu San*. 2015. Efficient free fatty acid production in engineered Escherichia coli strains using soybean oligosaccharides as feedstock. Biotechnology Progress. 31:686-694. (IF=1.947, JCR Q2)