吴海珍 照片

吴海珍

副教授

所属大学: 生物反应器工程国家重点实验室

所属学院: 未知

邮箱:
wuhzh@ecust.edu.cn

个人主页:
http://sklbe.ecust.edu.cn/Web/Show?w=146&p=106&f=469

个人简介

1975年3月出生,2000年获华东理工大学生物化学与分子生物学硕士学位并留任华东理工大学生物工程学院,2005年获华东理工大学生物化工博士学位,2007年升副教授。现任生物工程学院学位评定分委员会主任助理

研究领域

微生物分子生物学与鱼类免疫学,目前研究工作主要包括水产病原微生物持家酶GAPDH(甘油醛-3-磷酸脱氢酶)和FBA(果糖1,6-二磷酸醛缩酶)分泌机制的研究;鱼类疫苗的开发及作用机制研究

近期论文

1. Ni Ye, Haizhen Wu*, Yuanxing Zhang. Maternal transfer and protection role in zebrafish offspring following vaccination of the brood stock with a live attenuated Vibrio anguillarum vaccine. Aquaculture Research. 2015. DOI: 10.1111/are.12821

2. Xiaohong Liu, Hua Zhang, Yuan Gao, Yang Zhang, Haizhen Wu*, Yuanxing Zhang. Efficacy of chitosan oligosaccharide as aquatic adjuvant administrated with a formalin-inactivated Vibrio anguillarum vaccine. Fish and Shellfish Immmunolgoy. 2015. 47(2): 855-860

3. Zhongyang Sun, Binbing Shen, Haizhen Wu*, Xiangyu Zhou, Qiyao Wang, Jingfan Xiao, Yuanxing Zhang. The secreted fructose 1,6-bisphosphate aldolase as a broad spectrum vaccine candidate against pathogenic bacteria in aquaculture. Fish and Shellfish Immmunolgoy. 2015. 46(2): 638-647

4. Xiaohong Liu, Haizhen Wu*, Qin Liu, Qiyao Wang, Jinfan Xiao, Xinyue Chang, Yuanxing Zhang. Profiling immune response in zebrafish intestine, skin, spleen and kidney bath-vaccinated with a live attenuated Vibrio anguillarum vaccine. Fish and Shellfish Immunology. 2015. 45(2): 342-345

5. Hua Zhang, Haizhen Wu*, Liang Gao, Ying Qiu, Jingfan Xiao, Yuanxing Zhang. Identification, expression and immunological responses to bacterial challenge following vaccination of BLT1 gene from turbot, Scophthalmus maximus. Gene. 2015. 557(2): 229-235

6. Xiaohong Liu, Haizhen Wu*, Qin Liu, Qiyao Wang, Jinfan Xiao, Yuanxing Zhang. Skin-injured Zebrafish (Danio rerio) are more susceptible to Vibrio anguillarum Infection. Journal of the World Aquaculture Society. 2015. 46(3): 301-310

7. 唐宇飞, 刘晓红, 常馨月, 吴海珍*, 张元兴. 斑马鱼BLT1-like基因的克隆和表达分析. 水产学报. 2015. 39(12): 1753-1762

8. 董浩苏, 吴海珍*, 张元兴. 壳聚糖微纳米粒作为鱼类疫苗佐剂的应用研究. 华东理工大学学报. 2015. 41(6): 792-845

9. Xiaohong Liu, Xinyue Chang, Haizhen Wu*, Jingfan Xiao, Yuan Gao, Yuanxing Zhang. Role of intestinal inflammation in predisposition of Edwardsiella tarda infection in zebrafish (Danio rerio). Fish and Shellfish Immunology. 2014. 41(2): 271-278

10. Yuan Gao, Haizhen Wu*, Qiyao Wang, Jiangbo Qu, Qin Liu, Jingfan Xiao, Yuanxing Zhang. A live attenuated combination vaccine evokes effective immune-mediated protection against Edwardsiella tarda and Vibrio anguillarum. Vaccine. 2014. 32(45): 5937-5944

11. Yuan Gao, Yangyang Yi, Haizhen Wu*, Qiyao Wang, Jiangbo Qu, Yuanxing Zhang. Molecular cloning and characterization of secretory and membrane-bound IgM of turbot. Fish and Shellfish Immunology. 2014. 40(2): 354-361

12. Xiaohong Liu, Haizhen Wu*, Xinyue Chang, Yufei Tang, Qin Liu, Yuanxing Zhang. Notable mucosal immune responses induced in the intestine of zebrafish (Danio rerio) bath-vaccinated with a live attenuated Vibrio anguillarum vaccine. Fish and Shellfish Immunology. 2014. 40(2): 99-108

13. Hua Zhang, Binbing Shen, Haizhen Wu*, Liang Gao, Qin Liu, Qiyao Wang, Jingfan Xiao, Yuanxing Zhang. Th17-like immune response in fish mucosal tissues after administration of live attenuated Vibrio anguillarum via different vaccination routes. Fish and Shellfish Immunology. 2014, 37: 229-238

14. Zhihui Zhang, Haizhen Wu*, Jingfan Xiao, Qiyao Wang, Qin Liu, Yuanxing Zhang. Booster vaccination with live attenuated Vibrio anguillarum elicits strong protection despite weak specific antibody response in zebrafish. Journal of applied ichthyology. 2014. 30: 117-120

15. Hua Zhang, Chao Fei, Haizhen Wu*, Minjun Yang, Qin Liu, Qiyao Wang and Yuanxin Zhang. Transcriptome profiling reveals Th17-like immune responses induced in zebrafish bath-vaccinated with a live attenuated Vibrio anguillarum. PLOS ONE. 2013. 8(9): e73871

16. Zhihui Zhang, Haizhen Wu*, Jingfan Xiao, Qiyao Wang, Qin Liu, Yuanxing Zhang. Immune responses evoked by infection with Vibrio anguillarum in zebrafish bath-vaccinated with a live attenuated strain. Veterinary Immunology and Immunopathology. 2013, 154(3-4): 138-144

17. Shunqing Liang, Haizhen Wu*, Bing Liu, Jingfan Xiao, Qiyao Wang, Qin Liu and Yuanxing Zhang. Immune response of turbot, Scophthalmus maximus (L.), to a recombinant GAPDH of Edwardsiella tarda. Veterinary Immunology and Immunopathology. 2012, 15(3-4): 198-205

18. Meng Zhang, Haizhen Wu*, Xiaoyong Li, Minjun Yang, Tao Chen, Qiyao Wang, Qin Liu, Yuanxing Zhang. Edwardsiella tarda flagellar protein FlgD: a protective immunogen against edwardsiellosis. Vaccine. 2012, 30(26): 3849-56

19. Zhihui Zhang, Haizhen Wu*, Jingfan Xiao, Qiyao Wang, Qin Liu, Yuanxing Zhang. Immune responses of zebrafish (Danio rerio) induced by bath-vaccination with a live attenuated Vibrio anguillarum vaccine candidate. Fish and Shellfish Immunology. 2012, 33(1): 36-41

20. Xiaoyong Li, Haizhen Wu*, Meng Zhang, Shunqing Liang, Jingfan Xiao, Qiyao Wang, Qin Liu and Yuanxing Zhang. Secreted glyceraldehyde-3-phosphate dehydrogenase as a broad spectrum vaccine candidate against microbial infection in aquaculture. Letters in Applied Microbiology. 2012, 54(1): 1-9