林金萍 照片

林金萍

副研究员

所属大学: 生物反应器工程国家重点实验室

所属学院: 未知

邮箱:
jplin@ecust.edu.cn

个人主页:
http://sklbe.ecust.edu.cn/Web/Show?w=146&p=106&f=443

个人简介

生物化学与分子生物学专业硕士生导师,华东理工大学生物工程学院、生物反应器工程国家重点实验室副研究员

研究领域

新酶的筛选、发酵、纯化和功能表征; 酶的结构和功能解析; 生物催化合成手性化合物和生物基产品

近期论文

1.Jian Deng, Kangling Chen, Zhiqiang Yao, Jinping Lin?, Dongzhi Wei?. Towards the computational design and engineering of enzymeenantioselectivity: A case study by a carbonyl reductase from Gluconobacter oxydans. Journal of biotechnology.2016,217:31-40

2.Yuanyuan Shi, Kefei Li, Jinping Lin*, Dongzhi Wei, Shengli Yang. Engineered expression vectors significantly enhanced the production of 2-keto-D-gluconic acid by Gluconobacter oxydans. Journal of Agricultural and Food Chemistry.2015, 63(22): 5492?5498

3. Xingxing Zhang, Baoqi Zhang, Jinping Lin*, Dongzhi Wei. Oxidation of ethylene glycol to glycolaldehyde using a highly selective alcohol dehydrogenase from Gluconobacter oxydans. Journal of Molecular Catalysis B: Enzymatic. 2015,112: 69–75

4. Rong Chen, Xu Liu, Jiale Wang, Jinping Lin?, Dongzhi Wei?. Cloning, expression, and characterization of an anti-Prelog stereospeci?c carbonyl reductase from Gluconobacter oxydans DSM2343. Enzyme and Microbial Technology. 2015, 70: 18–27

5. Jian Deng, Kangling Chen, Zhiqiang Yao, Jinping Lin?, Dongzhi Wei?. Efficient synthesis of optically active halogenated aryl alcohols at highsubstrate load using a recombinant carbonyl reductase fromGluconobacter oxydans. Journal of Molecular Catalysis B: Enzymatic.2015, 118:1–7

6. Xu Liu, Rong Chen, Zhongwei Yang, Jiale Wang, Jinping Lin*, Dongzhi Wei*. Characterization of a Putative Stereoselective Oxidoreductase from Gluconobacter oxydans and Its Application in Producing Ethyl (R)-4-Chloro-3-Hydroxybutanoate Ester. Molecular Biotechnology, 2014, 56:285–295

7. Daihuan Li, Jinping Lin*, Dongzhi Wei*. Improving Gluconobacter oxydans performance in the in situ removal of the inhibitor for asymmetric resolution of racemic 1-phenyl-1,2-ethanediol. Bioresource Technology, 2014, 159: 327–333

8. Lulu Shi, Kefei Li, Huan Zhang, Xu Liu, Jinping Lin?, Dongzhi Wei?. Identification of a novel promoter gHp0169 for gene expression in Gluconobacter oxydans. Journal of Biotechnology. 2014, 175:69-74

9. Xu Liu, Chao Wang, Lujia Zhang, Zhiqiang Yao, Dongbing Cui, Liang Wu, Jinping Lin,* Y. Adam Yuan, Dongzhi Wei. Structural and mutational studies on an aldo-keto reductase AKR5C3 from Gluconobacter oxydans. Protein science. 2014 ,23(11):1540-9

10. Xu Liu, Zuanning Yuan, Y. Adam Yuan, Jinping Lin*, Dongzhi Wei*. Biochemical and structural analysis of Gox2181, a new member of the SDR superfamily from Gluconobacter oxydans. Biochemical and Biophysical Research Communications. 2011,415: 410-415

11. Jian Wu, Minhua Li, Jinping Lin*, Dongzhi Wei*. Highly Selective Oxidation of Benzyl Alcohol Using Engineered Gluconobacter Oxydans in Biphasic System. Current Microbiology. 2011, 62:1123-1127

12. Jian Wu, Jiale Wang, Minhua Li, Jinping Lin*, Dongzhi Wei*. Optimization of immobilization for selective oxidation of benzyl alcohol by Gluconobacter oxydans using response surface methodology. Bioresource Technology. 2010, 101:8936-8941

13. Minghua Li, Jian Wu, Xu Liu, Jinping Lin*, Dongzhi Wei*, Hao Chen. Enchanced production of dihydroxyacetone from glycerol by overexpression of glycerol dehydrogenase in an alcohol dehydrogenase-deficient mutant of Gluconobacter oxydans. Bioresource Technology. 2010, 101:8294-8299

14. Minghua Li, Jian Wu, Jinping Lin*, Dongzhi Wei. Expression of Vitreoscilla Hemoglobin Enhances Cell Growth and Dihydroxyacetone Production in Gluconobacter oxydans. Current Microbiology. 2010,61:370-375

15. Minmin Chen, Jinping Lin*, Yushu Ma, Dongzhi Wei. Characterization of a Novel NADPH-Dependent Oxidoreductase From Gluconobacter oxydans. Molecular biotechnology. 2010, 46:176-181

16. Lin Zhang, Jinping Lin*, Yushu Ma, Dongzhi Wei, Ming Sun.Construction of a novel shuttle vector for use in Gluconobacter oxydans. Molecular biotechnology. 2010, 46:227-233