王志菲，女，33岁，博士学历，专业方向：神经药理学。2002年华东师范大学生物学本科毕业，2007年中科院上海药物研究所神经药理学博士毕业。2008年至2014年，前往美国国立卫生研究院（NIH）担任访问学者、研究员。2014年9月，上海中医药大学副研究员。 Neuropsychopharmacology,JournalofCerebralBloodFlow&Metabolism,Neuropharmacology,Neurotheropeutics,PLOSONE,NeuroscienceLetters,JournaloftheNeurologicalSciences,Basic&ClinicalPharmacology&Toxicology,ActaPharmacologicaSinica,PharmaceuticalBiology等国际期刊应邀审稿人。发表学术论文20多篇。

中药活性成分对脑中风等中枢神经系统疾病的表观遗传学治疗机理研究；中药活性成分预处理干细胞对脑中风等他神经退行性疾病治疗作用及机理研究

1.LeedsPR,YuF,WangZ,ChiuCT,ZhangY,LengY,LinaresGR,ChuangDM.Anewavenueforlithium:interventionintraumaticbraininjury.ACSChemicalNeuroscience.2014Apr11.(Epubaheadofprint) 2.LengY,WangZ,TsaiLK,LeedsP,FesslerEB,WangJ,ChuangDM.FGF-21isanoveltargetofmoodstabilizingdrugsandhasarobustneuroprotectiverole.MolecularPsychiatry.2014Jan28.(Epubaheadofprint) 3.ChiuCT,WangZ,HunsbergerJG,ChuangDM.Therapeuticpotentialofmoodstabilizerslithiumandvalproicacid:beyondbipolardisorder.PharmacologicalReviews.2013,65(1):105-42. 4.YuF,WangZ,TanakaM,ChiuCT,LeedsP,ZhangY,ChuangDM.Posttraumacotreatmentwithlithiumandvalproate:reductionoflesionvolume,attenuationofblood-brainbarrierdisruption,andimprovementinmotorcoordinationinmicewithtraumaticbraininjury.JournalofNeurosurgery.2013,119(3):766-73. 5.FesslerEB,ChibaneFL,WangZ,ChuangDM.PotentialrolesofHDACinhibitorsinmitigatingischemia-inducedbraindamageandfacilitatingendogenousregenerationandrecovery.CurrentPharmaceuticalDesign.2013,19(28):5105-20. 6.WangZ,TsaiLK,MunasingheJ,LengY,FesslerEB,ChibaneF,LeedsP,ChuangDM.Chronicvalproatetreatmentenhancespost-ischemicangiogenesisandpromotesfunctionalrecoveryinaratmodelofischemicstroke.Stroke.2012,43(9):2430-6. 7.HunsbergerJG,FesslerEB,WangZ,ElkahlounAG,ChuangDM.Post-insultvalproicacid-regulatedmicroRNAs:potentialtargetsforcerebralischemia.AmericanJournalofTranslationalResearch.2012,4(3):316-32. 8.YuF,WangZ,TchantchouF,ChiuCT,ZhangY,ChuangDM.Lithiumamelioratesneurodegeneration,suppressesneuroinflammation,andimprovesbehavioralperformanceinamousemodeloftraumaticbraininjury.JournalofNeurotrauma.2012,29(2):362-74. 9.WangZ,LengY,TsaiLK,LeedsP,ChuangDM.Valproicacidattenuatesblood-brainbarrierdisruptioninaratmodeloftransientfocalcerebralischemia:rolesofhistonedeacetylaseandMMP-9inhibition.JournalofCerebralBloodFlowandMetabolism.2011,31(1):52-7. 10.WangZ,FesslerE,ChuangDM.Beneficialeffectsofmoodstabilizerslithium,valproateandlamotrigineinexperimentalstrokemodels.ActaPharmacologicaSinica.2011,32(12):1433-45. 11.TsaiLK*,WangZ*,MunasingheJ,LengY,LeedsP,ChuangDM.Mesenchymalstemcellsprimedwithvalproateandlithiumrobustlymigratetoinfarcted regionsandfacilitaterecoveryinastrokemodel.Stroke.2011,42(10):2932-9.(*Co-firstauthor) 12.ChuangDM,WangZ,ChiuCT.GSK-3asatargetforlithium-inducedneuroprotectionagainstexcitotoxicityinneuronalculturesandanimalmodelsofischemicstroke.FrontiersinMolecularNeuroscience.2011,4:15. 13.OmataN,ChiuCS,MoyaPR,LengY,WangZ,LeedsP,HunsburgJ,ChuangDM.LentivirallymediatedGSK-3βsilencinginthehippocampaldentategyrusinducesantidepressant-likeeffectsinstressedmice.InternationalJournalofNeuropsychopharmacology.2011,14(5):711-7. 14.TsaiLK,LengY,WangZ,LeedsP,ChuangDM.Themoodstabilizersvalproicacidandlithiumenhancemesenchymalstemcellmigrationviadistinctmechanisms.Neuropsychopharmacology.2010,35(11):2225-37. 15.ZhangHY,ZhengCY,YanH,WangZF,TangLL,GaoX,TangXC.PotentialtherapeutictargetsofhuperzineAforAlzheimer'sdiseaseandvasculardementia.Chemico-BiologicalInteractions.2008,175(1-3):396-402. 16.WangZF,WangJ,ZhangHY,TangXC.HuperzineAexhibitsanti-inflammatoryandneuroprotectiveeffectsinaratmodeloftransientfocalcerebralischemia.JournalofNeurochemistry.2008,106(4):1594-603. 17.WangZF,YanJ,FuY,TangXC,FengS,HeXC,BaiDL.PharmacodynamicstudyofFS-0311:anovelhighlypotent,selectiveacetylcholinesteraseinhibitor.CellularMolecularNeurobiology.2008,28(2):245-61. 18.WangZF,TangXC.HuperzineAprotectsC6ratgliomacellsagainstoxygen-glucosedeprivation-inducedinjury.FEBSLetters.2007,581(4):596-602. 19.HeXC,FengS,WangZF,ShiY,ZhengS,XiaY,JiangH,TangXC,BaiD.Studyondual-siteinhibitorsofacetylcholinesterase:Highlypotentderivativesofbis-andbifunctionalhuperzineB.Bioorganic&MedicinalChemistry.2007,15(3):1394-408. 20.WangZF,TangLL,YanH,WangYJ,TangXC.EffectsofhuperzineAonmemorydeficitsandneurotrophicfactorsproductionaftertransientcerebralischemiaandreperfusioninmice.PharmacologyBiochemistryandBehavior.2006,83(4):603-11. 21.FengS,WangZ,HeX,ZhengS,XiaY,JiangH,TangX,BaiD.Bis-huperzineB:highlypotentandselectiveacetylcholinesteraseinhibitors.JournalofMedicinalChemistry.2005,48(3):655-7. 22.WangZF,ZhouJ,TangXC.HuperzineBprotectsratpheochromocytomacellsagainstoxygen-glucosedeprivation-inducedinjury.ActaPharmacologicaSinica.2002,23(12):1193-8. 23.王志菲，唐希灿。脑缺血损伤的炎症反应及治疗策略展望。中国新药与临床杂志2007;26(6):454-461。 24.白东鲁，王志菲，冯松，唐希灿。石山碱的药理所用研究。《化学进展丛书——药物化学进展》，化学工业出版社，2005年。