翟光喜
教授
个人简介
1990.7-1993.9 山东医科大学口腔医院药师; 1996.7-2000.9 山东医科大学教师; 2000.9-至今 山东大学教师; 2003.4-2003.12 国家食品药品监督管理局药品审评中心外聘新药注册审评专家(借调工作); 1990.7本科毕业于山东医科大学,获学士学位; 1996.7研究生毕业于山东医科大学,获生化与微生物药物硕士学位; 2003.9毕业于沈阳药科大学,获药剂学专业博士学位; 2007.2山东大学药学博士后出站; 2007.3-2008.3美国俄亥俄州立大学药学院访问学者; 2016.10-2017.2丹麦哥本哈根大学药学院访问学者。
研究领域
药物缓控释、纳米靶向给药系统; 透皮吸收及鼻粘膜给药系统; 生物医学纳米材料及生物药物给药系统; 药物高端制剂及其产业化。
近期论文
1.Zhang Y, Khan AR , Yang X , Shi Y, Zhao X, Zhai G. A sonosensitiser-based polymeric nanoplatform for chemo-sonodynamic combination therapy of lung cancer. J Nanobiotech.2021 Feb 25; 19(1):57. (IF=10.435) 2.Li Y, Chen X,Ji J, Li L,Zhai G. Redox-responsive nanoparticles based on chondroitin sulfate and Docetaxel prodrug for tumor targeted delivery of Docetaxel. Carbohydr Polym. 2021 Aug 15;266:118133. (IF=9.381) 3.Shi X,Yang X, Liu M, Wang R,Qiu N, Liu Y, Yang H, Ji J,Zhai G. Chondroitin sulfate-based nanoparticles for enhanced chemo-photodynamic therapy overcoming multidrug resistance and lung metastasis of breast cancer. Carbohydr Polym.2021 Feb 15; 254:117459.(IF=9.381) 4.Wang R, Yang H, Rauf KA, Yang X, Xu J, Ji J,Zhai G. Redox-responsive hyaluronic acid-based nanoparticles for targeted photodynamic therapy/chemotherapy against breast cancer. J Colloid Interface Sci,2021 Sep 15;598:213-228.(IF=8.128) 5.Zhang Y, Qiu N, Zhang Y, Yan H, Ji J, Xi Y, Yang X, Zhao X,Zhai G.Oxygen-carrying nanoparticle-based chemo-sonodynamic therapy for tumor suppression and autoimmunity activation. Biomater Sci. 2021 Jun 4;9(11):3989-4004.(IF=6.843) 6.Yang X, Shi X, Zhang Y, Xu J, Ji J, Ye L, Yi F,Zhai G. Photo-triggered self-destructive ROS-responsive nanoparticles of high paclitaxel/chlorin e6 co-loading capacity for synergetic chemo-photodynamic therapy. J Control Release. 2020 Jul 10;323:333-349. (IF=9.776) 7. Shi X, Wang Y, Sun H, Chen Y, Zhang X, Xu J,Zhai G. Heparin-reduced graphene oxide nanocomposites for curcumin delivery: in vitro, in vivo and molecular dynamics simulation study. Biomater Sci. 2019 Feb 26; 7(3):1011-1027. (IF=5.251) 8.Chen Y, Khan AR, Yu D, Zhai Y, Ji J, Shi Y,Zhai G. Pluronic F127- functionalized molybdenum oxide nanosheets with pH-dependent degradability for chemo-photothermal cancer therapy. J Colloid Interface Sci. 2019 Oct 1;553:567- 580. (IF=6.361) 9.Liu M, Khan AR, Ji J, Lin G, Zhao X,Zhai G. Crosslinked self-assembled nanoparticles for chemo-sonodynamic combination therapy favoring antitumor, antimetastasis management and immune responses. J Control Release. 2018 Nov 28; 290:150-164. ( IF=7.901) 10.Liu M, Du H, Khan AR, Ji J, Yu A, Zhai G. Redox/enzyme sensitive chondroitin sulfate-based self-assembled nanoparticles loading docetaxel for the inhibition of metastasis and growth of melanoma. Carbohydr Polym. 2018 Mar 15; 184: 82-93. (IF= 5.158)