1999年7月研究生毕业于天津科技大学，获工学博士学位，同年进入山东大学微生物技术国家重点实验室博士后流动站，2001年8月出站留校工作，9月评聘为副教授，硕士生导师；2005年破格晋升教授，博士生导师。2006.9-2007.9加拿大康考迪亚大学生物系访问学者，2014.9-2015.3美国威斯康辛大学麦迪逊校区农业与生命科学学院高级研究学者。

1木质纤维素的生物降解和生物转化 （1）木质纤维素降解酶（如纤维素酶、半纤维素酶、木质素降解酶类、阿魏酸酯酶等）优良菌株的分子生物学改造 （2）酶的发酵生产及其应用； （3）木质纤维素不同组分的高效分离和转化利用技术（如生产纤维素乙醇、木糖醇、木质素产品等）。其中纤维素乙醇、木糖醇等已实现工业化规模生产。 2碱性/耐碱性酶类的研发及其应用 适合造纸、纺织、印染、食品等工业不同工艺要求的碱性/耐碱性酶制剂的研发和生产，例如碱性/耐碱性纤维素酶、碱性漆酶、碱性果胶酶等的高产菌株的工程改造和选育、工业用复合酶系研发、生产及其应用等。其中造纸工业用酶和碱性果胶酶已经成功应用于工业化生产。 3部分农副产品的深加工技术 如玉米、生姜等农产品中有效成分的分离提取、残渣的加工利用等

1 Tiantian Yang, Yingjie Guo, Na Gao, Xuezhi Li, Jian Zhao*.Modification of a cellulase system by engineering Penicillium oxalicum to produce cellulose nanocrystal,Carbohydrate Polymers, 2020, Vol 234, 115862 IF 7.182 (一区) 2 Tiantian Yang, Xuezhi Li, Yingjie Guo, Shengjuan Peng, Guodong Liu, Jian Zhao*.Effect of endoglucanases from different glycoside hydrolase families on enzymatic preparation of cellulose nanocrystal. Industrial Crops and Products,155(2020): 112755 IF4.244（一区） 3 Daolei Zhang, Xuezhi Li*, Jian Zhao*.Fusarium concolor X4 pretreatment suppresses light-induced yellowing of high-yield pulp.BioMed Research International, Volume 2020, Article ID 9497215 4 Fenfen Guo,Xuezhi Li*, Jian Zhao*, Guanxi Li, Peike Gao, Xiaolong Han. Optimizing Culture Conditions by Statistical Approach to Enhance Production of Pectinase fromBacillus sp. Y1. BioMed Research International. Volume 2019, Article ID 8146948 5 Yanan Li; Yueyan Hu; Zhu Zhu; Kaili Zhao; Guodong Liu; Lushan Wang; Yinbo Qu; Jian Zhao; Yuqi Qin*. Normal transcription of cellulolytic enzyme genes relies on the balance between the methylation of H3K36 and H3K4 inPenicillium oxalicum.Biotechnology for Biofuels, 2019, 12:198 （JCR一区），IF 6.343 6Ya'nan Li, Yueyan Hu, Kaili Zhao, Yunjun Pan, Yinbo Qu, Jian Zhao, Yuqi Qin*. The indispensable role of histone methyltransferase PoDot1 in extracellular glycoside hydrolase biosynthesis ofPenicillium oxalicum, Frontiers in Microbiology, 2019, 10: 2566（JCR一区） IF 4.840 7 Xianqin Lu, Xiaoting Feng, Xuezhi Li, Jian Zhao*. Binding and hydrolysis properties of engineered cellobiohydrolases and endoglucanases. Bioresource Technology, 2018. 267:235-241（一区）IF6.669 8 Xianqin Lu, Xiaoting Feng, Xuezhi Li, Jian Zhao*. The adsorption properties of endoglucanase to lignin and their impact on hydrolysis, Bioresource Technology, 2018. 267:110-116（一区）IF6.669 9 Can Wang, Xianqin Lu, Jia Gao, Xuezhi Li, Jian Zhao*. Xylo-oligosaccharides Inhibit Enzymatic Hydrolysis by Influencing Enzymatic Activity of Cellulase from Penicillium oxalicum, Energy & Fuels, 2018, 32:9427-9437 （二区） 10 Jian Du, Wenxia Song, Xiu Zhang, Jian Zhao, Guodong Liu, Yinbo Qu*, Differential Reinforcement of enzymatic hydrolysis by adding chemicals and accessory proteins to high solid loading substrates with different pretreatments. Bioprocess and Biosystems Engineering 2018, 41:1153-1163 11 Jian Du, Yuan Cao, Guodong Liu, Jian Zhao, Xuezhi Li, Yinbo Qu*. Identifying and overcoming the effect of mass transfer limitation on decreased yield in enzymatic hydrolysis of lignocellulose at high solid concentrations. Bioresource Technology, 2017，229:88-95（一区）IF5.807 12 Meimei Wang,·Yanxin Ye,·Xuezhi Li,·Hao Chen,·Jian Zhao*, Utility of co-expressed alkali-tolerant endoglucanase and xylanase in ameliorating wheat straw chemical pulp properties, Cellulose, 2017， 24(5), 2299-2311 (一区) 13Yanxin Ye, Xuezhi Li, Yuan Cao, Jian Du, Shicheng Chen, Jian Zhao*.A β-xylosidase hyper-production Penicillium oxalicum mutant enhanced ethanol production from alkali-pretreated corn stover. Bioresource Technology, 2017，245:734-742 （一区）IF5.807 14Yanxin Ye, Xuezhi Li, Jian Zhao*.Production and Characteristics of a Novel Xylose- and Alkali-tolerant GH 43 β-xylosidase fromPenicillium oxalicum for Promoting Hemicellulose Degradation. Scientific Reports, 2017, 7:11600 （二区） 15 Xianqin Lu, Can Wang, Xuezhi Li, Jian Zhao*. Temperature and pH influence adsorption of cellobiohydrolase onto lignin by changing the protein properties. Bioresource Technology, 2017，245：819-825 （一区） IF5.807 16 Meimei Wang, Jian Du, Daolei Zhang, Xuezhi Li, Jian Zhao*.Modification of Different Pulps by Homologous Overexpression Alkali-Tolerant Endoglucanase inBacillus subtilis Y106, Scientific Reports, 2017, 7:3321（二区） 17 Xianqin Lu, Can Wang, Xuezhi Li, Jian Zhao*, Xuebing Zhao.Studying nonproductive adsorption ability and binding approach of cellobiohydrolase to lignin during bioconversion of lignocellulose, Energy & Fuels, 2017,31 (12): 14393–14400,2017-10-19（二区） 18Liping Tan, Meimei Wang, Xuezhi Li, Hongxing Li,Jian Zhao*,Yinbo Qu, Yuen May Choo, Soh Kheang Loh. Fractionation of oil palm empty fruit bunch by bisulfite pretreatment for the production of bioethanol and high value products, Bioresource Technology, 2016, 200: 572-578 （一区） IF 5.651 19 Xianqin Lu,XiaojuZheng,Xuezhi Li, Jian Zhao*.Adsorption and mechanism of cellulase enzymes onto lignin isolated from corn stover pretreated with liquid hot water, Biotechnology for Biofuels, 2016, 9:118-129 （JCR一区），IF7.398 (5-years) 20 Daolei Zhang, Xuezhi Li*, Meimei Wang, Yanxin Ye, Jian Du, Xianqin Lu, Jian Zhao*. Xylanase Treatment Suppresses Light- and Heat-Induced Yellowing of Pulp, Scientific Reports, 2016,6:38374，（二区），IF5.525（5-years） 21 Yanan Li, Xiaoju Zheng, Xiujun Zhang, Longfei Bao, Yingying Zhu, Yinbo Qu, Jian Zhao*, Yuqi Qin*. The Different Roles of Penicillium oxalicum LaeA in the Production of Extracellular Cellulase andβ-xylosidase, Frontiers in Microbiology, 2016,7: 2091 (JCR一区)，IF 4.165