学习经历 2009/9-2012/6，山东大学，药学院生物技术研究所，博士； 2006/9-2009/6，山东大学，药学院药剂所，硕士； 2002/9-2006/6，山东大学，药学院，学士 工作经历 正高：2023.09-至今山东大学药学院新药药理研究所新药筛选平台 副高：2017.09-至今山东大学药学院新药药理研究所新药筛选平台 访问学者：2018.03-2019.09美国加州大学戴维斯分校 中级：2012.07-2017.08，山东大学药学院新药药理研究所新药筛选平台

纳米制剂递送给药 蛋白多肽类研究 外泌体的研究

1.Wei Pan, Hongyuan Chen, Aijun Wang, Fengshan Wang,Xinke Zhang（通讯作者）. Challenges and strategies: Scalable and efficient production of mesenchymal stem cells-derived exosomes for cell-free therapy. Life Sciences. 2023, 319, 121524. 2.Longkun Wang, Chunqian Zhao, Lu Lu, Honglei Jiang, Fengshan Wang,Xinke Zhang（通讯作者）. Transcytosable Peptide-Paclitaxel Prodrug Nanoparticle forTargeted Treatment of Triple-Negative Breast Cancer. International Journal of Molecular Sciences. 2023,24, 4646. 3.Shang Chen,Chenyan Ren,Yuan Ji,Dongke Liu,Xinke Zhang(通讯作者) ,Fengshan Wang.The Pharmacokinetics in Mice and Cell Uptake of Thymus Immunosuppressive Pentapeptide Using LC-MS/MS Analysis.Molecules,2022 ,27(13):4256. 4.Longkun Wang,Hongyuan Chen,Fengshan Wang,Xinke Zhang*(通讯作者). The development of peptide-drug conjugates (PDCs) strategies for paclitaxel. Expert Opin Drug Deliv. 2022,19(2):147-161. 5.Chunqian Zhao,Hongyuan Chen,Fengshan Wang,Xinke Zhang*(通讯作者). Amphiphilic self-assembly peptides: Rational strategies to design and delivery for drugs in biomedical applications. Colloids Surf B Biointerfaces,2021,208:112040. 6.Lin Zhao,Hongyuan Chen,Lu Lu, Chunqian Zhao, Christina V. Malichewe,Lei Wang,Xinke Zhang*(通讯作者),Xiuli Guo.Design and screening of a novel neuropilin-1 targeted penetrating peptide for anti-angiogenic therapy in glioma. Life Sciences, 2021,270,119113 7.Lin Zhao,Hongyuan Chen,Lu Lu,Lei Wang,Xinke Zhang*(通讯作者),Xiuli Guo. New insights into the role of co-receptor neuropilins in tumour angiogenesis and lymphangiogenesis and targeted therapy strategies.Journal of Drug Targeting. 2021,29(2):155-167 8.Lu Lu,Hongyuan Chen,Longkun Wang,Lin Zhao,Yanna Cheng,Aijun Wang,Fengshan Wang,Xinke Zhang*(通讯作者).A Dual Receptor Targeting- and BBB PenetratingPeptide Functionalized Polyethyleneimine Nanocomplex for Secretory Endostatin Gene Delivery to Malignant Glioma. International Journal of Nanomedicine, 2020, 15: 8875–8892. 9.Lu Lu,Chen Hongyuan,Hao Dake,Zhang Xinke*(通讯作者),Wang Fengshan. The functions and applications of A7R in anti- angiogenic therapy, imaging and drug delivery systems. Asian Journal of Pharmaceutical Sciences.2019,14(6):595-608 10.Xinke Zhang,Peng Li,Shaohua Guo,Shuqi Wang,Dasheng Liu.Quantitation ofβ-carboline and quercetin in alligator weed (Alternanthera philoxeroides (Mart.)