1990.09 ~ 1994.07 吉林农业大学中药材学院药用植物学专业，获农学学士学位。 1994.09 ~ 1995.07 吉林农业大学中药材学院，教师。 1995.09 ~ 1998.07 吉林农业大学中药材学院作物栽培与耕作学专业，获农学硕士学位。 1998.09 ~ 2001.07 北京大学医学部药学院生药学专业，获理学博士学位。 2001.12 ~ 2003.12 清华大学生物科学与技术系药物药理研究室，博士后。 2004.01 ~ 至今 山东大学药学院生药学研究所，教师。 2004.01 山东大学药学院生药学教研所， 讲师。 2005.09 山东大学药学院生药学教研所， 副教授。 2008.06 ~ 2009.06 美国约翰·霍普金斯大学医学院，访问学者。 2011.12 山东大学药学院生药学教研所， 教授。

中药活性成分研究

1. Hu SY, Chai WC, Xu LT, Li SQ, Jin CR, Zhu RX, Zhang RR, Tang KJ, Li P, Yang EL, Chang WQ, Shen T*, Semple S*, Venter H*,Xiang L*. Catecholic alkaloid sulfonates and aromatic nitro compounds fromPortulaca oleraceaand screening of their anti-inflammatory and anti-microbial activities.Phytochemistry, 2020, 181:112587. 2. Yang EL, Sun B, Huang ZY, Lin JG, Jiao B*,Xiang L*. Synthesis, purification, and selective β2-AR agonist and bronchodilatory effects of catecholic tetrahydroisoquinolines fromPortulaca oleracea.Journal of Natural Products, 2019, 82:2986-2993. 3. Jin TY, Li SQ, Jin CR, Shan H, Wang RM, Zhou MX, Li AL, Li LY, Hu SY, Shen T*,Xiang L*. Catecholic isoquinolines fromPortulaca oleraceaL. and their anti-inflammatory andβ2-adrenergic receptor agonist activity.Journal of Natural Products, 2018, 81(4):768-777. 4. Li LY, Jiao YN, Jin TY, Sun HX, Li SQ, Jin CR, Hu SY, Ji JB andXiang L*. Phenolic alkaloid oleracein E attenuates oxidative stress and neurotoxicity in AlCl3-treated mice.Life Sciences, 2017, 191:211-218. 5. Wang PP, Sun HX, Liu DY, Jiao ZZ, Yue S, He XQ, Xia W, Ji JB, Xiang L*. Protective effect of a phenolic extract containing indoline amides from Portulaca oleraceaagainst cognitive impairment in senescent mice induced by large dose of D-galactose /NaNO2.Journal of Ethnopharmacology, 2017, 203:252-259. 6.Sun HX, He XQ, Liu CJ, Li LY, Zhou RY, Jin TY, Yue S, Feng D, Gong J, Sun JW, Ji JB, Xiang L*. Effect of oleracein E, a neuroprotective tetrahydroisoquinoline, on rotenone-induced Parkinson’s disease cell and animal models.ACS Chemical Neuroscience, 2017, 8 (1):155-164. 7. Wang PP, Sun HX, Liu CJ, Hu MH, He XQ, Yue S, Jiao ZZ,Xiang L*. Racemic oleracein E increases the survival rate and attenuates memory impairment in D-galactose/NaNO2-induced senescent mice.Phytomedicine, 2016,23:460-467. 8.Jin TY, Shen T, Zhou MX, Li AL, Feng D, Zheng BL, Gong J, Sun JW, Li LY,Xiang L*. Chemical constituents fromPortulaca oleraceaand their bioactivities.Journal of Chinese Pharmaceutical Sciences, 2016, 25(12):898-905. 9. Jiao ZZ, Yue S, Sun HX, Jin TY, Wang HN, Zhu RX*,Xiang L*.Indoline amide glucosides fromPortulaca oleracea: isolation, structure, and DPPH radical scavenging Activity.Journal of Natural Products, 2015, 78 (11):2588-2597. 10. Yue S, Jiao ZZ, Sun HX, Jin TY,Xiang L*. A new tricyclic alkaloid fromPortulaca oleraceaL.Helvetica Chimica Acta, 2015, 98(7):961-966. 11.Jiao ZZ, Wang HN, Wang PP, Sun HX, Yue S,Xiang L*.Detection and quantification of cyclodopa amides inPortulaca oleraceaL. by HPLC-DAD and HPLC-ESI-MS/MS.Journal of Chinese Pharmaceutical Sciences, 2014, 23(8):533-542. 12. Liu DY, Shen T,Xiang L*. Two antioxidant alkaloids fromPortulaca oleraceaL.Helvetica Chimica Acta, 2011, 94:497-501. 13. Liu DY, Zhao GW,Xiang L*. Diverse strategies for the synthesis of the indoline scaffold.European Journal of Organic Chemistry, 2010, 21:3975-3984. 14. Yang ZJ, Liu CJ,Xiang L*, Zhen YN. Phenolic alkaloids as a new class of antioxidants inPortulaca oleracea.Phytotherapy Research, 2009, 23(7):1032-1035. 15. Xing J, Yang ZJ, Lv BB andXiang L*. Rapid screening for cyclo-dopa and diketopiperazine alkaloids in crude extracts ofPortulaca oleraceaL. using liquid chromatography/ tandem mass spectrometry.Rapid Communication Mass Spectrom, 2008, 22: 1415-1422. 16.向兰,郭东晓,鞠瑞,马彬,陈芸芸,杜力军.马齿苋的环二肽成分研究.中草药, 2007, 8(11): 1622-1625. 17.Xiang L, Xing DM, Wang W, Ding Y, Du LJ*. Alkaloids fromPortulaca oleraceaL. Phytochemistry, 2005, 66(21):2595-2601.