谭保才 照片

谭保才

教授

所属大学: 山东大学

所属学院: 生命科学学院

邮箱:
bctan@sdu.edu.cn

个人主页:
https://lifesci.sdu.edu.cn/info/1333/9387.htm

个人简介

教育背景 1992/09-1997/06 博士 佛罗里达大学(美国) 植物分子遗传学 1984/09-1987/06 硕士 兰州大学 植物生理学 1980/09-1984/06 学士 兰州大学 植物生理学 工作经历 2022/01- 至 今 山东大学特聘教授、泰山学者II期 2018/05-2020/12 山东大学(青岛)副校长、生命科学学院院长、山东大学特聘教授 2013/05-2022/01 山东大学生命科学学院院长、山东大学特聘教授、泰山学者 2011/01-2013/12 香港中文大学深圳研究院 研究员 2007/12-2013/12 香港中文大学植物分子与农业技术研究所 研究副教授 2001/03-2007/12 佛罗里达大学癌症与遗传研究所 研究助理教授 1997/07-2001/02 佛罗里达大学植物分子与细胞生物学 博士后 1992/08-1997/06 佛罗里达大学园艺科学系 研究助理 1987/06-1992/08 兰州大学生物系 讲师

研究领域

课题组主要以玉米为模式植物研究种子发育的分子遗传调控机制。种子发育与粮食作物的产量和品质密切相关,解析种子发育的分子遗传调控机制既是植物学的一个根本问题,也是农业生产高产优质育种的重要基础。种子发育过程涉及复杂的遗传调控网络,突变体是解析遗传网络组成元件的主要遗传材料。我们利用Mutator转座子分离了大量的玉米种子发育突变体,开发了针对性的基因克隆技术,通过基因克隆和遗传学、分子生物学和细胞生物学分析,查明这些基因的分子功能,解析调控种子发育的分子机制和调控网络,为分子育种提供理论基础。目前为止,实验室克隆了40多个玉米籽粒发育关键基因,通过功能解析,揭示了调控种子发育的重要途径并创新了相关的基础理论, 如确立了植物激素ABA是通过间接途径合成;发现了一个前所未知的阿魏酰蔗糖循环途径;该循环介导单子叶植物中细胞壁木聚糖阿魏酰化;初步解析了细胞器RNA编辑和内含子剪接的机制,为后续研究奠定了基础。其中,关于ABA合成途径的研究成果被编入美国《Plant Physiology》(Taiz & Zaiger ed.) 大学教材,并被翻译成中文等语言。实验室参与构建的UniformMu突变体库供全球科学家使用,成为玉米遗传学研究最重要的资源。

近期论文

1. Yang, D., Liu, H., Li, X., Zhang, Y.F., Zhang, X., Yang, H., Liu, M., Koch, K.E., McCarty, D.R., Li, S., Tan, B.C.* (2024). A sucrose ferulate cycle linchpin for ferulyolation of arabinoxylans in plant commelinids. Nature Plants DOI: 10.1038/s41477-024-01781-1. 2. Yang, Y.Z.*, Liu, X.Y., Gao, S., Zhang, S.G., Tan, B.C.* (2024). PPR21 is involved in the splicing of nad2 introns via interacting with PPR-SMR1 and SPR2 and is essential to maize seed development. J. Genet. Genomics DOI: 10.1016/j.jgg2024.08.010 3. Chen, B.#, Wang, J.#, Gui, Y., Wang, L., Wei, Q., Huang, M., Tan, B.C.* (2024). C1-FDX is required for the assembly of mitochondrial complexes I and V. PLoS Genetics (in press). 4. Wang, L., Chen, B., Ma, B., Wang, Y., Wang, H., Sun, X., Tan, B.C.* (2024). Maize Dek51 encodes a DEAD-box RNA helicase essential for pre-rRNA processing and seed development. Cell Reports 43, 114673. 5. Wang, Y., Huang, Z.Q., Tian, K.D., Li, H., Xu, C., Xia, B., Tan, B.C.* (2024). Multiple factors interact in the editing of the PPR-E+ targeted sites in maize mitochondria and plastids. Plant Commun. 5: 100836. 6. Liu X.Y., Jiang, R.C., Ma, B., Wang, Y., Yang, Y.Z., Xu, C., Sun, F., Tan, B.C.* (2024). Maize requires Embryo defective27 for embryogenesis and seedling development. Plant Physiology 195: 430-445. 7. Ma, B.#, Liu, H.#, Xiu, Z., Yang, H.H., Wang, H., Wang, Y., Tan, B.C.* (2024). Defective kernel 58 encodes an Rrp15p domain-containing protein essential to ribosome biogenesis and seed development in maize. New Phytologist 241: 1662-1675. 8. Yang Y.Z., Ding, S., Liu., X.Y., Xu, C., Sun, F., Tan, B.C.* (2023). The DEAD-box RNA helicase ZmRH48 is required for the splicing of multiple mitochondrial introns, mitochondrial complex biosynthesis, and seed development in maize. JIPB 65: 2456-2468. 9. Zu, X., Luo, L., Wang, Z., Gong, J., Yang, C., Deng, X., Song, X., Wang, Y., Xu, C., Qiao X., Chen, C., Tan, B.C., Cao, X.* (2023). A mitochondrial pentatricopeptide repeat protein enhances cold tolerance by modulating mitochondrial superoxide in rice. Nature Commun. 14: 6789. 10. Wang, Y., Li, H., Huang, Z.Q., Ma, B., Yang, Y.Z., Xiu, Z.H., Wang, L., Tan, B.C.* (2023). Maize PPR-E proteins mediate RNA C-to-U editing in mitochondria by recruiting the trans deaminase PCW1. Plant Cell 35: 529–551. 11. Yang, Y.Z.#, Liu, X.Y.#, Tang, J.J., Wang, Y., Xu, C., Tan, B.C.* (2022). GRP23 plays a core role in E-type editosomes via interacting with MORFs and atypical PPR-DYWs in Arabidopsis mitochondria. Proc. Natl. Acad. Sci. USA 119: e2210978119. 12. Liu, H., Xiu, Z., Yang, H., Ma, Z., Yang, D., Wang, H., Tan, B.C.* (2022). SHREK1 encoding a WD40 protein involves in ribosome biogenesis by regulating pre-rRNA processing in maize. Plant Cell 34: 4028-4044. 13. Cao, S.K.#, Liu, R.#, Wang, M., Sun, F., Sayyed, A., Shi, H., Wang, X., Tan, B.C.* (2022). (2022). Small PPR protein SPR2 interacts with PPR-SMR1 to facilitate the splicing of introns in maize mitochondria. Plant Physiology 190: 1763-1776. 14. Zhao, J.#, Cao, S.K.#, Li, X.L., Sun, F., Jiang, R.C., Xu, C.H., Tan, B.C.* (2022). Emp80 is required for mitochondrial nad7 and atp4 transcript editing and seed development in maize. New Phytologist 234: 1237-1248. 15. Wang F., Yu, Z., Zhang, M., Wang, M., Lu, X., Liu, X., Li, Y., Zhang, X., Tan, B.C., Li, C.*, Ding Z.* (2021). ZmTE1 promotes plant height by regulating intercalary meristem formation and internode cell elongation in maize. Plant Biotechnol. J. 20: 526-537. 16. Liu, X.Y., Jiang, R.C., Wang, Y., Tang, J.J., Sun, F., Yang, Y.Z., Tan, B.C.* (2021). ZmPPR26, a DYW-type pentatricopeptide repeat protein, is required for C-to-U RNA editing at atpA-1148 in maize chloroplasts. J. Exp. Bot. 72: 4809-4821. 17. Xu, C., Shen, Y., Li, C., Lu, F., Zhang, M.D., Meeley, R.B., McCarty, D.R. Tan, B.C.* (2021). Emb15 encodes a plastid ribosomal assembly factor essential for embryogenesis in maize. Plant J. 106: 214-227. 18. Yang, Y.Z., Ding, S., Liu, X.Y., Tang, J.J., Wang, Y., Sun, F., Xu, C., Tan, B.C.* (2021). EMP32 is required for the cis-splicing of nad7 intron 2 and seed development in maize. RNA Biology 18: 499-509. 19. Xu, C., Song, S., Yang, Y.Z., Lu, F., Zhang, M.D., Sun, F., Jia, R., Song, R., Tan, B.C.* (2020). DEK46 performs C-to-U editing of a specific site in mitochondrial nad7 introns that is critical for intron splicing and seed development in maize. Plant J. 103: 1767-1782. 20. Liu, R., Cao, S.K., Sayyed, A., Yang, H.H., Zhao J., Wang, X.M., Jia, R.X., Sun, F., Tan, B.C.* (2020). The DYW-subgroup pentatricopeptide repeat protein PPR27 interacts with ZmMORF1 to facilitate mitochondrial RNA editing and seed development in maize. J. Exp. Bot. 71: 5495-5505. 21. Wang, H.C., Sayyed, A., Liu, X.Y., Yang, Y.Z., Sun, F., Wang, Y., Wang, M.D., Tan, B.C.* (2020). SMALL KERNEL4 is required for mitochondrial cox1 transcript editing and seed development in maize. JIPB. 62: 777-792. 22. Wang Y., Liu, X.Y., Yang, Y.Z., Huang, J., Sun, F., Lin, J.S., Gu, Z.Q., Sayyed, A., Xu, C., Tan, B.C.* (2019). Empty pericarp21 encodes a novel PPR-DYW protein that is required for mitochondrial RNA editing at multiple sites, complexes I and V biogenesis, and seed development in maize. PLoS Genetics 15(8): e1008305. 23. Chen, Z.#, Wang, H.C.#, Shen, J., Sun, F., Wang M.D. Xu, C., Tan, B.C.* (2019). PPR-SMR1 is required for the splicing of multiple mitochondrial introns and interacts with Zm-mCSF1 and is essential for seed development in maize. J. Exp. Bot. 70: 5245-5258. 24. Sun, F., Xiu, Z., Jiang, R., Liu, Y., Zhang, X., Yang, Y.Z., Li, X., Zhang, X., Wang, Y., Tan, B.C.* (2019). The mitochondrial pentatricopeptide repeat protein EMP12 is involved in the splicing of three nad2 introns and seed development in maize. J. Exp. Bot. 70: 963-972. 25. Li, X.L., Huang, W.L., Jiang R.C., Sun, F., Wang, H.C., Zhao, J., Xu, C., Tan, B.C.* (2019). EMP18 functions in mitochondrial atp6 and cox2 transcript editing and is essential to seed development in maize. New Phytologist 221: 896-907. 26. Sun, F., Zhang, X., Shen, Y., Wang, H., Liu, R., Wang, X., Gao, D., Yang, Y.Z., Liu, Y., Tan, B.C.* (2018). The pentatricopeptide repeat protein EMPTY PERICARP8 is required for the splicing of three mitochondrial introns and seed development in maize. Plant J. 95: 919-932. 27. Zhang Y.F., Suzuki M., Sun F., Tan B.C.* (2017). The mitochondrion-targeted PENTATRICOPEPTIDE REPEAT78 protein is required for nad5 mature mRNA stability and seed development in maize. Molecular Plant 10: 1321-1333. 28. Yang Y.Z., Ding S., Wang Y., Li C.L., Shen Y., Meeley R., McCarty D.R., Tan B.C.* (2017). Small kernel2 encodes a glutaminase in Vitamin B6 biosynthesis and is essential for maize seed development. Plant Physiology 174: 1127-1138. 29. Cai M., Li S., Sun F., Sun Q., Zhao H., Ren X., Zhao Y., Tan B.C., Zhang Z.*, Qiu F.* (2017). Emp10 encodes a mitochondrial PPR protein that affects the cis-splicing of nad2 intron 1 and seed development in maize. Plant J. 91: 132-144. 30. Tan B.C., Guan J.C., Ding S., Wu S., Koch K.E., McCarty D.R.* (2017). Structure and origin of the White Cap locus and its role in the evolution of grain color in maize. Genetics 206: 135-150. 31. Yang Y.Z., Ding S., Wang H.C., Sun F., Huang W.L., Song S., Xu C.H., Tan B.C.* (2017). The pentatricopeptide repeat protein EMP9 is required for mitochondrial ccmB and rps4 transcript editing, mitochondrial complex biogenesis and seed development in maize. New Phytologist 214: 782-795. 32. Xiu Z., Sun F., Shen Y., Zhang X., Jiang R., Bonnard G., Zhang J., Tan B.C.* (2016). EMPTY PERICARP16 is required for mitochondrial nad2 intron 4 cis-splicing and seed development in maize. Plant J. 85: 507-519. 33. Li C., Shen Y., Meeley R., McCarty D.R., Tan, B.C.* (2015). Embryo defective 14 encodes a plastid-targeted cGTPase essential for embryogenesis in maize. Plant J. 84: 785-799. 34. Sun F., Wang X., Bonnard G., Shen Y., Xiu Z., Li, X., Gao, D., Zhang, Z., Tan B.C.* (2015). Empty pericarp 7 encodes a mitochondrial E-subgroup pentatricopeptide repeat protein that is required for ccmFN editing, mitochondrial function and seed development in maize. Plant J. 84: 283-295. 35. Chen Y., Hou M., Liu L., Wu S., Shen Y., Ishiyama K., Kobayashi M., McCarty D.R., Tan B.C.* (2014). The maize DWARF 1 encodes a Gibberellin 3-oxidase and is dual-localized to the nucleus and cytosol. Plant Physiology 166: 2028-2039. 36. Li X.J., Zhang Y.F., Hou M.M., Sun F., Shen Y., Xiu Z.H., Wang X.M., Chen Z.L., Sun S.S.M., Small I., Tan B.C.* (2014). Small kernel 1 encodes a pentatricopeptide repeat protein required for mitochondrial nad7 transcript editing and seed development in maize and rice. Plant J. 79: 797–809. 37. Shen Y., Li C., Meeley R., McCarty D.R., Tan B.C.* (2013). Embryo defective 12 encodes translation initiation factor 3 and is essential to maize embryogenesis. Plant J. 74: 792-804. 38. Liu Y., Xiu Z.H., Meeley R., Tan B.C.* (2013). Empty pericarp 5 encodes a pentatricopeptide repeat protein that is required for mitochondrial RNA editing and seed development in maize. Plant Cell 25: 868-883. 39. Messing S.A., Gabelli S.B., Echeverria I., Vogel J.T., Guan J.C., Tan B.C., Klee H.J., McCarty D.R., Amzel L.M. (2010). Structural insights into maize Viviparous14, a key enzyme in the biosynthesis of the phytohormone abscisic acid. Plant Cell 22: 2970-2980. 40. Vogel J.T., Tan B.C., McCarty D.R., Klee H.J. (2008). The carotenoid cleavage dioxygenase 1 enzyme has broad substrate specificity, cleaving multiple carotenoids at two different bond positions. J. Biol. Chem. 283: 11364-1137. 41. McCarty D.R., Settles A.M., Suzuki M., Tan B.C., Latshaw S., Porch T., Robin K., Baier J., Avigne W., Lai J., Messing J., Koch K.E., Hannah L.C. (2005). Steady-state transposon mutagenesis in inbred maize. Plant J. 44: 52-61. 42. Tan B.C.*, Joseph L.M., Deng W.T., Liu L.J., Li Q.B., Cline K., McCarty D.R. (2003). Molecular characterization of the Arabidopsis nine-cis-expoxycarotenoid dioxygenase gene family. Plant J. 35: 44-56. 43. Tan B.C.*, Cline K., McCarty D.R. (2001). Localization and targeting of VP14 epoxy-carotenoid dioxygenase to the chloroplast membrane. Plant J. 27: 373-382. 44. Tan B.C., Schwartz S., Zeevaart J.A., McCarty D.R.* (1997). Genetic control of abscisic acid synthesis in maize. Proc. Natl. Acad. Sci. USA 94: 12235-12240. 45. Schwartz S.#, Tan B.C.#, Gage D.A., Zeevaart J.A., McCarty D.R.* (1997). Specific oxidative cleavage of carotenoids by VP14 of maize. Science 276: 1872-1875.